Implementation of the QbD Approach to the Analytical Method Development and Validation for the Estimation of the Treprostinil Injection Dosage Form by RP-HPLC. [PDF]
Alluri NR +3 more
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Quality-by-Design-Driven RP-HPLC Method Development and Validation for Impurity Analysis of Elexacaftor, a Cystic Fibrosis Drug, with LC-MS/MS-Based Degradant Identification. [PDF]
Raghupathi JK +7 more
europepmc +1 more source
Technical note: optimizing and validating an RP-HPLC method to determine lactoferrin in porcine colostrum and milk. [PDF]
Metzger K, Gimsa U, Otten W.
europepmc +1 more source
Eco-friendly RP-HPLC method for simultaneous determination of water-soluble and fat-soluble vitamins in nano-formula and pharmaceutical dosage forms. [PDF]
Salah El-Din SH, Mahmoud AM, Morsi A.
europepmc +1 more source
Estimation of CDK inhibitors by RP-HPLC: application for pharmacokinetic interactions studies with PPIs. [PDF]
Desai MP +3 more
europepmc +1 more source
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RP-HPLC Binding Domains of Proteins
Analytical Chemistry, 1998Procedures have been developed to identify the chromatographic binding domains of horse heart cytochrome c (Cyt c) and bovine growth hormone (bGH) during their interaction with reversed-phase sorbent materials. The procedure involves adsorption of the protein solute to the chromatographic sorbent, followed by proteolytic cleavage.
Aguilar, Marie-Isabel +6 more
openaire +4 more sources
Assay of CCNU in Tumor by RP-HPLC
Artificial Cells, Blood Substitutes, and Biotechnology, 2005This paper reports a RP-HPLC method for the determination of Lomustine (CCNU) in mouse tumor tissue. CCNU was separated and determined on a reverse-phase C18 5 microm column with a mobile phase of H2O-acetonitrile (54:46), detected at 254 nm and no internal standard. The calibration curve was linear (r = 0.9999) within the range of 0.98-15.68 microg/ml
Zhao, Z. Q. +3 more
openaire +2 more sources
Estimation of Lopinavir by RP-HPLC
Research Journal of Pharmacy and Technology, 2019Simple, sensitive and accurate HPLC method has been developed for the estimation of Lopinavir in pharmaceutical dosage forms. Lopinavir is an antiretroviral drug. Chromatographic separation was conducted on phenomenex lunar (250x4.6mm, 5µ) column at temperature 35°C, using a mobile phase composition of Acetonitrile: Water (70:30). The flow rate was 1ml/
D K Deepthi +3 more
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Quantification of Pitolisant: A RP - HPLC study
YMER Digital, 2022Objective An attempt was made to develop a simple, isocratic and robust reverse phase high performance liquid chromatographic method for Pitolisant. Material and methods An Inertsil octa decyl silane column and photo diode array detector were employed for the quantification of Pitolisant at 268 nm using a mobile phase consisting of acetonitrile and 0.1
Sowjanya Gummadi +1 more
openaire +1 more source

