Results 201 to 210 of about 59,105 (258)

Nano‐Gs Protein Peptidomimetics: Rational Design of Gα C‐Terminus‐Derived Peptides Mimicking Key Components of Gs‐β2AR Interactions

Angewandte Chemie International Edition, Volume 65, Issue 24, 8 June 2026.
G protein‐coupled receptors (GPCRs) are major therapeutic targets. Modulating GPCR activity through intracellular sites is evolving. A structure‐ and computation‐assisted approach generated small G protein‐derived peptidomimetics targeting the intracellular binding crevice of the β2 adrenergic receptor mimicking features of the full G protein.
Phuong Thu Tran, Mia Danielsen, Johanna K. S. Tiemann, Passainte Ibrahim, Søren G. F. Rasmussen, Xavier Kubiak, Hossein Batebi, Charlène Gadais, Steven Ballet, Peter W. Hildebrand, Daniel Sejer Pedersen, Jesper Mosolff Mathiesen   +11 more
wiley   +1 more source

Development of RP-HPLC Method for Simultaneous Determination of Triclabendazole and Ivermectin in Pharmaceutical Suspension Dosage Form. [PDF]

J Anal Methods Chem
Rahman TU, Zaman A, Bahadur A, Zeb MA, Liaqat W, Santali EY, Alharthi S, Omar RMK, Alharthy SA, Ali A.   +9 more
europepmc   +1 more source

Chemical Syntheses of 3′ and 5′ Phosphorylated Oligonucleotides: An Overview

European Journal of Organic Chemistry, Volume 29, Issue 21, 4 June 2026.
This review provides an overview of the various chemical methods employed in the synthesis of oligonucleotides bearing a phosphate group at their 3′ or 5′ end. Notably, it presents modified phosphoramidites and supports developed for this purpose. Oligonucleotides (ON) with a phosphate monoester group at their 3′ or 5′ end have applications in many ...
Rémy Lartia
wiley   +1 more source

A new RP-HPLC approach for estimation of potential impurities of Fosamprenavir - method development and validation. [PDF]

BMC Pharmacol Toxicol
Godela R, Nelson VK, Nuli MV, Jaini PK, Pathak S, Ponnekanti K, Suryadevara PR, Burle GS, Mayasa V, Kesari KK.   +9 more
europepmc   +1 more source

Exploring Diverse Glycone Preferences of Aspergillus rutinosidases

Advanced Synthesis &Catalysis, Volume 368, Issue 11, 3 June 2026.
Rutinosidases from Aspergillus niger (AnRut) and A. oryzae (AoRut) catalyze hydrolysis and transglycosylation with non‐natural glycosides as donors, enabling glycosylation of alcoholic and phenolic acceptors. AnRut exhibits broad glycone promiscuity, while AoRut has a narrower substrate scope.
Jitka Brouzdová, Lucie Petrásková, Katerina Brodsky, Natalia Kulik, Helena Pelantová, Martina Hurtová, Andrea Vopálenská, Kristýna Slámová, Pavla Bojarová, Vladimír Křen   +9 more
wiley   +1 more source

RP-HPLC Method for Rhein Quantification in Cassia fistula L. (Fabaceae) Leaves. [PDF]

Acta Med Philipp
Rodriguez JP.
europepmc   +1 more source

Synergistic CuMoP Nanocomposite‐Modified Carbon Electrode for Ultrasensitive Detection of Aspirin

ChemElectroChem, Volume 13, Issue 11, 3 June 2026.
A CuMoP ternary system‐modified screen‐printed carbon electrode is developed via a one‐step electrodeposition strategy for the electrochemical detection of aspirin. The synergistic Cu–Mo–P redox network promotes efficient electron–proton coupling, enabling reliable and reproducible sensing.
Hong Wan, Mingfang Zhan, Minglan Ma, Sima Akter, Chunyan Yin, Sakil Mahmud   +5 more
wiley   +1 more source

Green and white analytical approach for parallel quantification of gabapentin and methylcobalamin in medicinal products using inventive RP-HPLC technique. [PDF]

Sci Rep
Mahgoub SM, Alminderej FM, Binsaleh AY, Alsehli BR, Saleh SM, Mohamed MA.   +5 more
europepmc   +1 more source

An eco-friendly bioanalytical RP-HPLC method coupled with fluorescence detection for simultaneous estimation of felodipine and metoprolol. [PDF]

BMC Chem
Beniamin MW, Kessiba AM, Hegazy MA, El Gendy AE, Kormod LA.   +4 more
europepmc   +1 more source

A systemic approach to estimate and validate RP-HPLC assay method for remdesivir and favipiravir in capsule dosage form. [PDF]

PLoS One
Khan NU, Iqbal M, Khan BA.
europepmc   +1 more source