Results 221 to 230 of about 97,740 (305)

A new RP-HPLC approach for estimation of potential impurities of Fosamprenavir - method development and validation. [PDF]

open access: yesBMC Pharmacol Toxicol
Godela R   +9 more
europepmc   +1 more source

Biophysical characterization of Cyclophilin B reveals membrane localization as its primary functional determinant as a prolyl isomerase

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract The endoplasmic reticulum (ER) provides a specialized environment for the folding of secreted and membrane proteins, a process supported by many different chaperones. Among these chaperones, peptidyl‐prolyl cis/trans isomerases (PPIases) catalyze a rate‐limiting conformational step in protein folding, yet the principles governing isoform ...
Sarah C. DeVoe   +7 more
wiley   +1 more source

Influence of Peptide‐Based Chelator Sequences on HER2‐Targeting Radiopeptide

open access: yesJournal of Peptide Science, Volume 32, Issue 5, May 2026.
Peptide‐based chelator consisting of Cys‐Gly‐Gly‐Gly incorporated into HER2‐targeting rL‐A9 peptide for 99mTc‐labeling. [99mTc]Tc‐CGGG‐rL‐A9 exhibited high binding affinity and tumor uptake and retention. ABSTRACT In our pursuit of developing HER2‐targeting radiolabeled peptides for detection and therapy of HER2‐positive breast cancer, the previously ...
Sonal Gupta   +5 more
wiley   +1 more source

Spatial Variability in Trace Organic Compound Reactivity During Urban River Infiltration Into an Alluvial Aquifer

open access: yesWater Resources Research, Volume 62, Issue 5, May 2026.
Abstract Trace organic compounds (TrOCs) in lotic systems pose risks for ecosystem and human health. TrOCs can enter groundwater along losing river sections, yet little is known about the spatial extent of infiltration zones and the biogeochemical factors controlling the spatial variability of TrOC reactivity and removal, particularly along river‐to ...
Jonas L. Schaper   +6 more
wiley   +1 more source

Fermented Fish Products: A Comprehensive Overview of Traditional Processing Techniques, Varieties, and Their Health Benefits

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT This review addresses the processing aspects and integrates in vitro and in vivo findings to highlight the various health benefits of indigenous fermented fish products from different regions of the world. Across Asia, Africa, and Northern Europe, fermented fish holds cultural significance, with each region boasting unique varieties shaped by ...
Banlambhabok Khongthaw   +6 more
wiley   +1 more source

Upregulation of sphingomyelin and ABCA8 in response to TDP‐43 pathology in amyotrophic lateral sclerosis brain

open access: yesBrain Pathology, Volume 36, Issue 3, May 2026.
Increases in sphingomyelin in response to TDP‐43 pathology in the disease‐affected motor cortex of amyotrophic lateral sclerosis (ALS) brain. Abstract Amyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disease characterized by the degeneration of motor neurons and the presence of TAR DNA‐binding protein 43 (TDP‐43 ...
Finula I. Isik   +4 more
wiley   +1 more source

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