Results 51 to 60 of about 37,396 (213)

Mutations in rpoB and katG genes of multidrug resistant mycobacterium tuberculosis undetectable using genotyping diagnostic methods

The Pan African Medical Journal, 2017
INTRODUCTION: Tuberculosis remains the leading causes of death worldwide with frequencies of mutations in rifampicin and isoniazid resistant Mycobacterium tuberculosis isolates varying according to geographical location.
Faustinos Tatenda Takawira, Racheal Shamiso Dube Mandishora, Zephaniah Dhlamini, Ellen Munemo, Babill Stray-Pedersen   +4 more
doaj   +1 more source

Molecular characterization of rpoB gene mutations in isolates from tuberculosis patients in Cubal, Republic of Angola

BMC Infectious Diseases, 2021
Background The importance of Mycobacterium tuberculosis strains with disputed rpoB mutations remains to be defined. This study aimed to assess the frequency and types of rpoB mutations in M. tuberculosis isolates from Cubal, Angola, a country with a high
Ariadna Rando-Segura, María Luisa Aznar, María Milagros Moreno, Mateu Espasa Soley, Elena Sulleiro Igual, Cristina Bocanegra Garcia, Eva Gil Olivas, Arlete Nindia Eugénio, Carlos Escartin Huesca, Adriano Zacarias, Josep Vegue Collado, Domingos Katimba, Maria Carmen Vivas Cano, Estevao Gabriel, Maria Teresa López García, Tomas Pumarola Suñe, Israel Molina Romero, María Teresa Tórtola Fernández   +17 more
doaj   +1 more source

The mutation rate of rpoB gene showed an upward trend with the increase of MIRU10, MIRU39 and QUB4156 repetitive number

BMC Genomics, 2023
Background Mycobacterial interspersed repetitive unit-variable number tandem repeat (MIRU-VNTR) is a frequently used typing method for identifying the Beijing genotype of Mycobacterium tuberculosis (Mtb), which is easily transformed into rifampicin (RIF)
Fan Su, Lei Cao, Xia Ren, Jian Hu, Grace Tavengana, Huan Wu, Yumei Zhou, Yuhan Fu, Mingfei Jiang, Yufeng Wen   +9 more
doaj   +1 more source

Presence of New Delhi metallo-β-lactamase gene (NDM-1) in a clinical isolate of Acinetobacter junii in Argentina [PDF]

, 2016
Here we report the presence of a clinically significant A. junii blaNDM-1 positive in a 38-year-old woman who was admitted to the emergency department with a fever and leg ulcers with signs of infection.
Almuzara, Marisa, Barberis, Claudia, Cittadini, Roxana, Del Castillo M,, Lazzaro, T., Montaña, Sabrina Daiana, Ramírez, M. S., Uong, S., Vay, Carlos Alberto   +8 more
core   +1 more source

Sequence and analysis of the rpoB gene of Mycobacterium smegmatis [PDF]

Antimicrobial Agents and Chemotherapy, 1995
The rpoB gene encodes the beta subunit of the DNA-dependent RNA polymerase of bacteria. Mutations in defined areas result in resistance to rifampin. Mycobacterium smegmatis is naturally resistant to rifampin, but analysis of the rpoB gene revealed no identifiable rifampin resistance mutations. Another mechanism of resistance may be present.
S V, Hetherington, A S, Watson, C C, Patrick   +2 more
openaire   +2 more sources

Rarity of rpoB Mutations Outside the Rifampicin Resistance-Determining Region of Mycobacterium tuberculosis Isolates from Patients Responding Poorly to First-Line Tuberculosis Regimens in Beijing, China: A Retrospective Study

Infection and Drug Resistance, 2021
Jidong Guo,1,* Rongmei Liu,1,* Jin Shi,1,* Fengmin Huo,2 Yuanyuan Shang,3 Fen Wang,2 Mengqiu Gao,1 Shanshan Li3 1Department of Tuberculosis, Beijing Chest Hospital, Capital Medical University/Beijing Tuberculosis & Thoracic Tumor Research ...
Guo J, Liu R, Shi J, Huo F, Shang Y, Wang F, Gao M, Li S   +7 more
doaj  

Molecular evidence of lateral gene transfer in rpoB gene of Mycobacterium yongonense strains via multilocus sequence analysis. [PDF]

PLoS ONE, 2013
Recently, a novel species, Mycobacterium yongonense (DSM 45126(T)), was introduced and while it is phylogenetically related to Mycobacterium intracellulare, it has a distinct RNA polymerase β-subunit gene (rpoB) sequence that is identical to that of ...
Byoung-Jun Kim, Seok-Hyun Hong, Yoon-Hoh Kook, Bum-Joon Kim   +3 more
doaj   +1 more source

rpoB Gene Sequence-Based Identification of Staphylococcu s Species [PDF]

Journal of Clinical Microbiology, 2002
ABSTRACT The complete sequence of rpoB , the gene encoding the beta subunit of RNA polymerase was determined for Staphylococcus saccharolyticus , Staphylococcus lugdunensis , S taphylococcus caprae , and Staphylococcus ...
Michel, Drancourt, Didier, Raoult
openaire   +2 more sources

New and Improved Diagnostics for Detection of Drug-Resistant Pulmonary Tuberculosis. [PDF]

, 2011
PURPOSE OF REVIEW: Tuberculosis (TB) remains a global emergency and continues to kill 1.7 million people globally each year. Drug-resistant TB is now well established throughout the world and most TB patients are not being screened for drug resistance ...
Affolabi, Albert, Banerjee, Blakemore, Boehme, Brossier, Bwanga, Caws, Coronel, Drews, Ellner, Ellner, Farnia, Fears, Garza-González, Gupta, Helb, Hillemann, Kiet, Kim, Lemaire, Lin, Ling, Martin, Martin, Martin, Migliori, Migliori, Minion, Morcillo, Neonakis, Nicol, Pai, Palomino, Piersimoni, Sandgren, Sohn, Van Rie, Visalakshi, Visalakshi, Wallis, Wright   +41 more
core   +1 more source

Interpreting very low Mycobacterium tuberculosis detected on Xpert Mycobacterium tuberculosis/rifampicin

Lung India, 2019
The development and rollout of the Xpert® Mycobacterium tuberculosis/rifampicin assay for the GeneXpert platform is considered an important breakthrough in the fight against tuberculosis.
Kanchan Ajbani, Swapna Naik, Mubin Kazi, Anjali Shetty, Camilla Rodrigues   +4 more
doaj   +1 more source