Results 61 to 70 of about 38,542 (258)

Impact of rpoB Mutations on Reduced Vancomycin Susceptibility in Staphylococcus aureus [PDF]

Journal of Clinical Microbiology, 2011
ABSTRACT Of 38 vancomycin-intermediate Staphylococcus aureus (VISA) clinical strains, 27 (71%) possessed a mutation(s) in rpoB encoding the β-subunit of RNA polymerase. Furthermore, 95.6% of the rifampin-resistant mutants obtained from 9 methicillin-resistant S. aureus
Yukiko, Watanabe, Longzhu, Cui, Yuki, Katayama, Kishii, Kozue, Keiichi, Hiramatsu   +4 more
openaire   +2 more sources

Characterization of Genetic Variants Associated with Rifampicin Resistance Level in Mycobacterium tuberculosis Clinical Isolates Collected in Guangzhou Chest Hospital, China

Infection and Drug Resistance, 2022
HM Adnan Hameed1– 4*, Cuiting Fang1– 4*, Zhiyong Liu,1– 3 Yanan Ju,1– 3 Xingli Han,1– 4 Yamin Gao,1– 4 Shuai Wang,1– 3,5 Gift Chiwala,1– 4 Yaoju Tan,6 Ping Guan,6 Jinxing Hu,6 Xiaoli Xiong,1– 3 Jiacong Peng,3,7 Yongping Lin,3,7 Muzammal Hussain,4
Hameed HMA, Fang C, Liu Z, Ju Y, Han X, Gao Y, Wang S, Chiwala G, Tan Y, Guan P, Hu J, Xiong X, Peng J, Lin Y, Hussain M, Zhong N, Maslov DA, Cook GM, Liu J, Zhang T   +19 more
doaj  

Occurrence of disputed rpoB mutations among Mycobacterium tuberculosis isolates phenotypically susceptible to rifampicin in a country with a low incidence of multidrug-resistant tuberculosis

BMC Infectious Diseases, 2019
Background Accurate drug susceptibility testing (DST) of Mycobacterium tuberculosis in clinical specimens and culture isolates to first-line drugs is crucial for diagnosis and management of multidrug-resistant tuberculosis (MDR-TB).
Noura M. Al-Mutairi, Suhail Ahmad, Eiman Mokaddas, Hanaa S. Eldeen, Susan Joseph   +4 more
doaj   +1 more source

Pseudomonas cyclic lipopeptides suppress the rice blast fungus Magnaporthe oryzae by induced resistance and direct antagonism [PDF]

, 2019
Beneficial Pseudomonas spp. produce an array of antimicrobial secondary metabolites such as cyclic lipopeptides (CLPs). We investigated the capacity of CLP-producing Pseudomonas strains and their crude CLP extracts to control rice blast caused by ...
Batool, Humaira, De Mot, Rene, Höfte, Monica, Omoboye, Olumide Owolabi, Oni, Feyisara Eyiwumi, Yimer, Henok Zimene   +5 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Phylogenetic analysis of Mycobacterium massiliense strains having recombinant rpoB gene laterally transferred from Mycobacterium abscessus. [PDF]

PLoS ONE, 2017
Recent multi locus sequence typing (MLST) and genome based studies indicate that lateral gene transfer (LGT) events in the rpoB gene are prevalent between Mycobacterium abscessus complex strains. To check the prevalence of the M.
Byoung-Jun Kim, Ga-Na Kim, Bo-Ram Kim, Tae-Sun Shim, Yoon-Hoh Kook, Bum-Joon Kim   +5 more
doaj   +1 more source

New and Improved Diagnostics for Detection of Drug-Resistant Pulmonary Tuberculosis. [PDF]

, 2011
PURPOSE OF REVIEW: Tuberculosis (TB) remains a global emergency and continues to kill 1.7 million people globally each year. Drug-resistant TB is now well established throughout the world and most TB patients are not being screened for drug resistance ...
Affolabi, Albert, Banerjee, Blakemore, Boehme, Brossier, Bwanga, Caws, Coronel, Drews, Ellner, Ellner, Farnia, Fears, Garza-González, Gupta, Helb, Hillemann, Kiet, Kim, Lemaire, Lin, Ling, Martin, Martin, Martin, Migliori, Migliori, Minion, Morcillo, Neonakis, Nicol, Pai, Palomino, Piersimoni, Sandgren, Sohn, Van Rie, Visalakshi, Visalakshi, Wallis, Wright   +41 more
core   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

New Insight regarding Legionella Non-Pneumophila Species Identification: Comparison between the Traditional mip Gene Classification Scheme and a Newly Proposed Scheme Targeting the rpoB Gene

Microbiology Spectrum, 2021
The identification of Legionella non-pneumophila species (non-Lp) in clinical and environmental samples is based on the mip gene, although several studies suggest its limitations and the need to expand the classification scheme to include other genes. In
Maria Rosaria Pascale, Silvano Salaris, Marta Mazzotta, Luna Girolamini, Giulia Fregni Serpini, Laura Manni, Antonella Grottola, Sandra Cristino   +7 more
doaj   +1 more source

Compounding Effects of Climate Warming and Antibiotic Resistance. [PDF]

, 2020
Bacteria have evolved diverse mechanisms to survive environments with antibiotics. Temperature is both a key factor that affects the survival of bacteria in the presence of antibiotics and an environmental trait that is drastically increasing due to ...
Cruz-Loya, Mauricio, Lozano-Huntelman, Natalie, Rodríguez-Verdugo, Alejandra, Savage, Van, Yeh, Pamela   +4 more
core   +1 more source