Results 141 to 150 of about 3,138,640 (295)

Analysis of 35 pre-rRNA processing by circular RT-PCR.

, 2016
(A) The diagram shows various pre-rRNA processing intermediates amplified by 18S cRT-PCR. (B) Increased accumulation of 18S-A3 intermediates in rh7-5 mutant. Representative EtBr-stained 1.5% (w/v) gels for 18S rRNA cRT-PCR are shown.
Yuelin Liu (3172434), Daisuke Tabata (3172437), Ryozo Imai (176667)   +2 more
core   +1 more source

Microalgae Hybrid Biosystem for Enhanced Oral Delivery of Rifaximin in Hepatic Encephalopathy Treatment

Advanced Science, EarlyView.
The microalgae‐nanoparticle hybrid system with antibacterial activity can improve the oral delivery and therapeutic efficiency for hepatic encephalopathy treatment. Oral administration of the system can reduced systemic ammonia levels, enhanced intestinal barrier function, attenuated systemic and neuroinflammation, ameliorated cognitive impairments ...
Kaiyue Wang, Xueting Huang, Lingxiao Yang, Jin Liu, Lei Lei, Shaomin Zou, Kai Wang, Min Zhou, Zhe Tang   +8 more
wiley   +1 more source

Do we need a standardized 16S rRNA gene amplicon sequencing analysis protocol for poultry microbiota research?

Poultry Science
Bacteria are the major component of poultry gastrointestinal tract (GIT) microbiota and play an important role in host health, nutrition, physiology regulation, intestinal development, and growth.
Joshua M. Lyte, Mitiku M. Seyoum, Diana Ayala, Jannigje G. Kers, Valentina Caputi, Timothy Johnson, Li Zhang, Joshua Rehberger, Guolong Zhang, Sami Dridi, Brett Hale, Jean E. De Oliveira, Daniel Grum, Alexandra H. Smith, Michael Kogut, Steven C. Ricke, Anne Ballou, Bill Potter, Monika Proszkowiec-Weglarz   +18 more
doaj   +1 more source

The evolutionarily conserved protein Las1 is required for pre-rRNA processing at both ends of ITS2.

, 2012
Ribosome synthesis entails the formation of mature rRNAs from long precursor molecules, following a complex pre-rRNA processing pathway. Why the generation of mature rRNA ends is so complicated is unclear.
Ludivine Wacheul, Stéphanie Schillewaert, Lafontaine, Denis, Frédéric Lhomme, Denis L. J. Lafontaine, Wacheul, Ludivine, Schillewaert, Stéphanie, Lhommé, Frédéric   +7 more
core   +1 more source

Frequent Sweetened Beverage Consumption Is Associated With Accelerated Biological Aging: Evidence From a Population‐Based Study and Gut Microbiota Analysis

Advanced Science, EarlyView.
Frequent sweetened beverage consumption is associated with accelerated biological aging in a large Chinese population. Five gut microbial genera are consistently enriched in both frequent sweetened beverage consumers and individuals with accelerated aging and show significant mediating effects, suggesting a potential microbiota‐related pathway linking ...
Yuwei Shi, Xinmei Li, Yufan Hao, Qiaoyu Wu, Yuji Yu, Siyu Li, Nuo Xu, Yi‐Hsuan Wu, Eunhye Lee, Chi Chang, Emily Hu, Ying Lu, Elizabeth Delzell, Ann W. Hsing, Shankuan Zhu   +14 more
wiley   +1 more source

Mouse nucleolus-like body supports transcription and enhances processing of rRNA in porcine enucleolated oocytes

Macedonian Veterinary Review
Fully-grown mammalian oocytes contain morphologically evident but transcriptionally inactive nucleoli called “nucleolus-like bodies” (NLBs). These nuclear structures are essential for early embryonic development.
Martin Morovic, Frantisek Strejcek, Michal Benc, Alexandra Rosenbaum Bartkova, Sara Stachovicova, Florina Popovska-Percinic, Monika Dovenska, Jozef Laurincik   +7 more
doaj   +1 more source

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing. [PDF]

Nucleic Acids Res, 2023
Chen Y, Li Y, Dai RS, Savage JC, Shinde U, Klimek J, David LL, Young EA, Hafner M, Sears RC, Sun XX, Dai MS.   +11 more
europepmc   +1 more source

Cobalt Single‐Atom Nanozyme for Enhanced Intestinal Radioprotection and Tumor Radiosensitization via Bidirectional ROS Modulation

Advanced Science, EarlyView.
Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Shengqi Yin, Junjie Li, Yishu Zou, Yang Liu, Yilin Zheng, Lu Yu, Wanying Zheng, Yajun Zou, Zehui Zhang, Tao Li, Peiqun Yin, Jianlin Zhang, Yuen Wu, Yi Ding   +13 more
wiley   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

Advanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal, Ubaid Tariq, Shreya Mehrotra, Saravanan Matheshwaran, Jan Marsal, Ashok Kumar   +5 more
wiley   +1 more source

Rate of transcription elongation and sequence-specific pausing by RNA polymerase I directly influence rRNA processing. [PDF]

J Biol Chem, 2022
Huffines AK, Engel KL, French SL, Zhang Y, Viktorovskaya OV, Schneider DA.   +5 more
europepmc   +1 more source