Results 21 to 30 of about 15,343 (276)

Inbreeding Calculated with Runs of Homozygosity Suggests Chromosome-Specific Inbreeding Depression Regions in Line 1 Hereford

Animals, 2021
The goal of this study was to evaluate inbreeding in a closed beef cattle population and assess phenotype prediction accuracy using inbreeding information.
Bethany Pilon, Kelly Hinterneder, El Hamidi A. Hay, Breno Fragomeni   +3 more
doaj   +1 more source

Heterozygosity and homozygosity regions affect reproductive success and the loss of reproduction: A case study with litter traits in pigs

Computational and Structural Biotechnology Journal, 2022
Runs of heterozygosity (ROHet) and homozygosity (ROH) harbor useful information related to traits of interest. There is a lack of investigating the effect of ROHet and ROH on reproductive success and the loss of reproduction in mammals. Here, we detected
Zitao Chen, Zhenyang Zhang, Zhen Wang, Zhe Zhang, Qishan Wang, Yuchun Pan   +5 more
doaj   +1 more source

Runs of Homozygosity Islands in Autochthonous Spanish Cattle Breeds. [PDF]

Genes (Basel)
Background/Objectives: Understanding the genetic architecture of autochthonous European cattle breeds is important for developing effective conservation strategies and sustainable breeding programs. Spanish beef cattle, which trace their origins to ancient migrations from the Near East with later admixture from African populations, exhibit a rich ...
Hervás-Rivero C, Mejuto-Vázquez N, López-Carbonell D, Altarriba J, Diaz C, Molina A, Rodríguez-Bermúdez R, Piedrafita J, Baro JA, Varona L.   +9 more
europepmc   +7 more sources

Correlation of Genomic and Pedigree Inbreeding Coefficients in Small Cattle Populations

Animals, 2021
This study aimed to identify inbreeding coefficient (F) estimators useful for improvement programs in a small Holstein population through the evaluation of different methodologies in the Mexican Holstein population.
José Cortes-Hernández, Adriana García-Ruiz, Carlos Gustavo Vásquez-Peláez, Felipe de Jesus Ruiz-Lopez   +3 more
doaj   +1 more source

Runs of homozygosity and testicular cancer risk [PDF]

Andrology, 2019
AbstractBackgroundTesticular germ cell tumour (TGCT) is highly heritable but > 50% of the genetic risk remains unexplained. Epidemiological observation of greater relative risk to brothers of men with TGCT compared to sons has long alluded to recessively acting TGCT genetic susceptibility factors, but to date none have been reported.
Loveday, C., Sud, A., Litchfield, K., Levy, M., Holroyd, A., Broderick, P., Kote-Jarai, Z., Dunning, A.M., Muir, K., Peto, J., Eeles, R., Easton, D.F., Dudakia, D., Orr, N., Pashayan, N., Rustin, Gordon, Srihari, Narayanan N., Cole, David, Askill, Colin, Bertelli, Gianfilippo, Barber, James, Gilby, Ed, White, Jeff, Baybrooke, Jeremy, Leahy, Michael, Welch, Richard, Chakraborti, Prabir, Joffe, Johnathan, Brown, Richard, Faust, Guy, Simmonds, Peter, Mazhar, Danish, Stockdale, Andrew, Hrounda, David, Humber, Caroline, Appel, Wiebke, Hong, Anne, Howard, Grahame, Douglas, Fiona, Bloomfield, David, Butt, Mohammad, Kelly, Kay, Mehra, Rakesh, Brown, Richard, Rogers, Paul, Chakraborti, Prabir, Hatton, Matthew, Hennig, Ivo, McAteer, John, Savage, Philip, Seckl, Michael, Gale, Joanna, Rustin, Gordon, Clark, Peter, Woby, Steve, Rathmell, Adrian, Lamont, Alan, Sarwar, Naveed, Stuart, Nick, Chowdhury, Simon, Beesley, Sharon, Winkler, Mathius, Hamid, Abdel, Pathak, Sanjeev, Madhavan, Krishnaswamy, Highley, Martin, Money-Kryle, Julian, Brock, Cathryn, Sreenivasan, Thiagarajan, Henderson, Brian E., Haiman, Christopher A., Schumacher, Fredrick R., Al Olama, Ali Amin, Benlloch, Sara, Berndt, Sonja I., Conti, David V., Wiklund, Fredrik, Chanock, Stephen, Gapster, Susan, Stevens, Victoria L., Tangen, Catherine M., Batra, Jyotsna, Clements, Judith, Gronberg, Henrik, Schleutker, Johanna, Albanes, Demetrius, Wolk, Alicja, West, Catharine, Mucci, Lorelei, Cancel-Tassin, Geraldine, Koutros, Stella, Sorensen, Karina Dalsgaard, Maehle, Lovise, Neal, David E., Hamdy, Freddie C., Donovan, Jenny L., Travis, Ruth C., Hamilton, Robert J., Ingles, Sue Ann, Rosenstein, Barry S., Lu, Yong-Jie, Giles, Graham G., Kibel, Adam S., Vega, Ana, Kogevinas, Manolis, Penney, Kathryn L., Park, Jong Y., Stanford, Janet L., Cybulski, Cezary, Nordestgaard, Borge G., Brenner, Hermann, Maier, Christiane, Kim, Jeri, John, Esther M., Teixeira, Manuel R., Neuhausen, Susan L., De Ruyck, Kim, Razack, Azad, Newcomb, Lisa F., Lessel, Davor, Kaneva, Radka, Usmani, Nawaid, Claessens, Frank, Townsend, Paul A., Dominguez, Manuela Gago, Roobol, Monique J., Menegaux, Florence, Khaw, Kay-Tee, Cannon-Albrigh, Lisa, Pandha, Hardev, Thibodeau, Stephen N., Reid, A., Huddart, R.A., Houlston, R.S., Turnbull, C.   +134 more
openaire   +4 more sources

Genomic prediction based on runs of homozygosity [PDF]

Genetics Selection Evolution, 2014
Genomic prediction is based on the accurate estimation of the genomic relationships among and between training animals and selection candidates in order to obtain accurate estimates of the genomic estimated breeding values (GEBV). Various methods have been used to predict GEBV based on population-wide linkage disequilibrium relationships (G IBS ) or ...
Luan T., Yu X., Dolezal M., Bagnato A., Meuwissen T. H.   +4 more
openaire   +3 more sources

Runs of Homozygosity Revealed Reproductive Traits of Hu Sheep

Genes, 2022
Hu sheep, a famous breed in the Taihu Basin, has the advantages of non-seasonal estrus, multiple fetuses, coarse feeding tolerance, and suitability for house feeding. Runs of homozygosity (ROHs) were found to be an effective tool to detect the animal population structure and economic traits.
Yuzhe Li, Zitao Chen, Yifei Fang, Caiyun Cao, Zhe Zhang, Yuchun Pan, Qishan Wang   +6 more
openaire   +2 more sources

Runs of homozygosity and inbreeding in thyroid cancer [PDF]

BMC Cancer, 2016
Genome-wide association studies (GWASs) have identified several single-nucleotide polymorphisms (SNPs) influencing the risk of thyroid cancer (TC). Most cancer predisposition genes identified through GWASs function in a co-dominant manner, and studies have not found evidence for recessively functioning disease loci in TC.
Thomsen H, Chen B, Figlioli G, ELISEI, ROSSELLA, ROMEI, CRISTINA, CIPOLLINI, MONICA, CRISTAUDO, ALFONSO, Bambi F, Hoffmann P, Herms S, LANDI, STEFANO, Hemminki K, GEMIGNANI, FEDERICA, Försti A.   +13 more
openaire   +2 more sources

Signatures of selection in the genome of Swedish warmblood horses selected for sport performance

BMC Genomics, 2019
Background A growing demand for improved physical skills and mental attitude in modern sport horses has led to strong selection for performance in many warmblood studbooks.
Michela Ablondi, Åsa Viklund, Gabriella Lindgren, Susanne Eriksson, Sofia Mikko   +4 more
doaj   +1 more source

Estimates of autozygosity through runs of homozygosity in farmed coho salmon [PDF]

Genes, 2020
AbstractThe characterization of runs of homozygosity (ROH), using high-density single nucleotide polymorphisms (SNPs) allows inferences to be made about the past demographic history of animal populations and the genomic ROH has become a common approach to characterize the inbreeding.
Grazyella M. Yoshida, Pablo Cáceres, Rodrigo Marín-Nahuelpi, Ben F. Koop, José M. Yáñez   +4 more
openaire   +3 more sources