Results 11 to 20 of about 5,649 (188)

Best Practices and Gaps in Current Regulatory and Health Technology Assessment Real-World Evidence Policies for Medicines and Medical Devices: Current State of Play and Next Steps. [PDF]

Clin Transl Sci
ABSTRACT Real‐world data (RWD) offers a valuable opportunity to access vast information that can drive research and generate real‐world evidence (RWE), offering insights into the actual delivery of care and patient outcomes beyond the limitations of traditional clinical trials.
Cresswell K, Claire R, Issa L, Kubehl L, Bilal O, Purcell R, Clemente A, Wested J, Jensen LG, Sasane M, Peeters R, Shinkins B, Colvin H.   +12 more
europepmc   +2 more sources

RWE Framework: An Interactive Visual Tool to Support a Real-World Evidence Study Design

Drugs - Real World Outcomes, 2019
Objectives Real-world evidence (RWE) is essential for the development of pharmaceutical and medical technologies and informs treatment-related decisions by regulatory agencies, payers, healthcare providers, and patients.
Andrew D. Xia, Caroline P. Schaefer, Agota Szende, Elke Jahn, Matthew J. Hirst   +4 more
doaj   +1 more source

Teaching Real-World Evidence: Protocol for a Systematic Review

JMIR Research Protocols, 2020
BackgroundReal-world evidence (RWE) refers to observational health care data beyond clinical trial data. It holds the promise of transforming health care as a new form of evidence to support decision makers in making decisions when developing and ...
Lam, Ching, van Velthoven, Michelle Helena, Chaudhury, Hassan, Meinert, Edward   +3 more
doaj   +1 more source

Using artificial intelligence to identify patients with migraine and associated symptoms and conditions within electronic health records

BMC Medical Informatics and Decision Making, 2023
Background Real-world evidence (RWE)—based on information obtained from sources such as electronic health records (EHRs), claims and billing databases, product and disease registries, and personal devices and health applications—is increasingly used to ...
Daniel Riskin, Roger Cady, Anand Shroff, Nada A. Hindiyeh, Timothy Smith, Steven Kymes   +5 more
doaj   +1 more source

Real world evidence (RWE) – a disruptive innovation or the quiet evolution of medical evidence generation? [version 1; referees: 2 approved]

F1000Research, 2018
Stakeholders in healthcare are increasingly turning to real world evidence (RWE) to inform their decisions, alongside evidence from randomized controlled trials.
Sajan Khosla, Robert White, Jesús Medina, Mario Ouwens, Cathy Emmas, Tim Koder, Gary Male, Sandra Leonard   +7 more
doaj   +1 more source

Real world evidence (RWE) – a disruptive innovation or the quiet evolution of medical evidence generation? [version 2; referees: 2 approved]

F1000Research, 2018
Stakeholders in healthcare are increasingly turning to real world evidence (RWE) to inform their decisions, alongside evidence from randomized controlled trials.
Sajan Khosla, Robert White, Jesús Medina, Mario Ouwens, Cathy Emmas, Tim Koder, Gary Male, Sandra Leonard   +7 more
doaj   +1 more source

AMA- and RWE- Based Adaptive Kalman Filter for Denoising Fiber Optic Gyroscope Drift Signal

Sensors, 2015
An improved double-factor adaptive Kalman filter called AMA-RWE-DFAKF is proposed to denoise fiber optic gyroscope (FOG) drift signal in both static and dynamic conditions.
Gongliu Yang, Yuanyuan Liu, Ming Li, Shunguang Song   +3 more
doaj   +1 more source

Awareness, Knowledge, and Utility of RCT Data vs RWE: Results From a Survey of US Cardiologists: Real-world Evidence in Clinical Decision Making

Clinical Medicine Insights: Cardiology, 2020
Real-world evidence (RWE) provides a potential rich source of additional information to the body of data available from randomized clinical trials (RCTs), but there is a need to understand the strengths and limitations of RWE before it can be applied to ...
Todd C Villines, Mark J Cziraky, Alpesh N Amin   +2 more
doaj   +1 more source

EA3: A softmax algorithm for evidence appraisal aggregation.

PLoS ONE, 2021
Real World Evidence (RWE) and its uses are playing a growing role in medical research and inference. Prominently, the 21st Century Cures Act-approved in 2016 by the US Congress-permits the introduction of RWE for the purpose of risk-benefit assessments ...
Francesco De Pretis, Jürgen Landes
doaj   +1 more source

Identifying Themes of Right-Wing Extremism in Hindutva Discourse on Twitter

Social Media + Society, 2023
Hindutva, the core political ideology of India’s current ruling party, the Bharatiya Janata Party (BJP), seeks to transform constitutionally secular India into a Hindu Rashtra (“Hindu nation”).
Piyush Ghasiya, Georg Ahnert, Kazutoshi Sasahara   +2 more
doaj   +1 more source