Results 61 to 70 of about 2,075 (199)

Relaxin-Family Peptide Receptors 1 and 2 Are Fully Functional in the Bovine

Frontiers in Physiology, 2017
In most mammals the peptide hormone relaxin is a key physiological component regulating early pregnancy and birth. However, synteny analysis shows that the gene encoding ovarian relaxin-2 is deleted in cows and sheep.
Yanzhenzi Dai, Yanzhenzi Dai, Richard Ivell, Richard Ivell, Richard Ivell, Xuan Liu, Dana Janowski, Ravinder Anand-Ivell, Ravinder Anand-Ivell   +8 more
doaj   +1 more source

INSL3 as a biomarker of Leydig cell functionality [PDF]

, 2013
Insulin-like factor 3 (INSL3) is a small peptide hormone made and secreted uniquely by mature Leydig cells in the testes of all mammals. Importantly, this expression and secretion appears to be constitutive and therefore reflects the differentiation ...
Anand-Ivell, Ravinder, Ivell, Richard, Wade, John D.   +2 more
core   +1 more source

Synthesis of fluorescent analogues of relaxin family peptides and their preliminary in vitro and in vivo characterization

Frontiers in Chemistry, 2013
Relaxin, a heterodimeric polypeptide hormone, is a key regulator of collagen metabolism and multiple vascular control pathways in humans and rodents.
Linda eChan, Linda eChan, Craig eSmith, Craig eSmith, Berenice eChua, Feng eLin, Ross eBathgate, Ross eBathgate, Ross eBathgate, Frances eSeparovic, Andrew eGundlach, Andrew eGundlach, M. Akhter eHossain, M. Akhter eHossain, M. Akhter eHossain, John eWade, John eWade, John eWade   +17 more
doaj   +1 more source

The evolving role of whole-exome sequencing in the management of disorders of sex development

Endocrine Connections, 2021
Objective: Disorders of sex development (DSD) are defined as congenital co nditions in which the development of chromosomal, gonadal and anatomical sex is atypical.
Yardena Tenenbaum-Rakover, Osnat Admoni, Ghadir Elias-Assad, Shira London, Marie Noufi-Barhoum, Hanna Ludar, Tal Almagor, Yoav Zehavi, Charles Sultan, Rita Bertalan, Anu Bashamboo, Kenneth McElreavey   +11 more
doaj   +1 more source

A multi-trait meta-analysis with imputed sequence variants reveals twelve QTL for mammary gland morphology in Fleckvieh cattle [PDF]

, 2016
Background The availability of whole-genome sequence data from key ancestors in bovine populations provides an exhaustive catalogue of polymorphic sites that segregate within and across cattle breeds.
Hermann Schwarzenbacher, Hubert Pausch, Reiner Emmerling, Ruedi Fries   +3 more
core   +8 more sources

Examination of relaxin and its receptors expression in pig gametes and embryos

Reproductive Biology and Endocrinology, 2011
Background Relaxin is a small peptide also known as pregnancy hormone in many mammals. It is synthesized by both male and female tissues, and its secretions are found in various body fluids such as plasma serum, ovarian follicular fluid, utero-oviduct ...
Bathgate Ross A, Willard Scott T, Rodriguez-Munoz Juan C, Feugang Jean M, Ryan Peter L   +4 more
doaj   +1 more source

Expression and Role of INSL3 in the Fetal Testis

Frontiers in Endocrinology, 2022
Insulin-like peptide 3 (INSL3) is a small peptide hormone of the insulin-relaxin family which is produced and secreted by the fetal Leydig cells in the testes only. It appears to be undetectable in female fetuses.
Richard Ivell, Linn Salto Mamsen, Claus Yding Andersen, Ravinder Anand-Ivell   +3 more
doaj   +1 more source

Progress of genome wide association study in domestic animals [PDF]

, 2012
Domestic animals are invaluable resources for study of the molecular architecture of complex traits. Although the mapping of quantitative trait loci (QTL) responsible for economically important traits in domestic animals has achieved remarkable results ...
Hui Li, Hui Zhang, Shouzhi Wang, Zhipeng Wang   +3 more
core   +1 more source

A genome-wide association study identifies a genomic region for the polycerate phenotype in sheep (Ovis aries) [PDF]

, 2016
201
Chen, Ze-Hui, Kantanen, Juha, Li, Meng-Hua, Peng, Wei-Feng, Ren, Xue, Shen, Min, Wu, Fu-An, Yang, Guang-Li, Zhang, Min, Zhao, Yong-Xin   +9 more
core   +1 more source

Characterizing relaxin receptor expression and exploring relaxin’s effect on tissue remodeling/fibrosis in the human bladder

BMC Urology, 2020
Background Relaxin is an endogenous protein that has been shown to have antifibrotic properties in various organ systems. There has been no characterization of relaxin’s role in the human bladder.
Edward C. Diaz, Mason Briggs, Yan Wen, Guobing Zhuang, Shannon L. Wallace, Amy D. Dobberfuhl, Chia-Sui Kao, Bertha C. Chen   +7 more
doaj   +1 more source