Results 81 to 90 of about 2,075 (199)
Eda haplotypes in three-spined stickleback are associated with variation in immune gene expression [PDF]
, 2017 Haplotypes underlying local adaptation and speciation are predicted to have numerous phenotypic effects, but few genes involved have been identified, with much work to date concentrating on visible, morphological, phenotypes.A El Nagar, A Smahi, A Zapata, A-L Ducrest, ADC MacColl, ADC MacColl, AK Greenwood, C Cluzeau, C Eizaguirre, C Eizaguirre, C Lexer, CR Linnen, CR Linnen, D Schluter, DJ Rennison, DQ Tran, DV Chan, F Mackay, FC Jones, FC Jones, G Rauch, J De Roij, JP Scharsack, JSC Arthur, KB Marchinko, M Hammer, M Probst-Kepper, MA Bell, MG Mills, MW Pfaffl, NH Barton, O Seehausen, P Brassard, P Nosil, PF Colosimo, PF Colosimo, R Hopkins, RD Barrett, RD Barrett, RD Reed, RDH Barrett, S Robertson, S Robertson, S Wisniewski, S Yeaman, SE Johnston, SE Johnston, SF Owen, T Henrich, TJ Little, Y Sun +50 morecore +2 more sourcesComparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits
Advanced Science, Volume 13, Issue 17, 23 March 2026.A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...Bingru Zhao, Hanpeng Luo, Dailu Guan, Xuefeng Fu, Feng Wang, Guoming Zhang, Shanglai Li, Hua Yang, Yanli Zhang +8 morewiley +1 more sourceActivation of relaxin family receptor 1 from different mammalian species by relaxin peptide and small-molecule agonist ML290 [PDF]
, 2015 Relaxin peptide (RLN), which signals through the relaxin family peptide 1 (RXFP1) GPCR receptor, has shown therapeutic effects in an acute heart failure clinical trial.Alexander I Agoulnik, Amaya eBueno, Brian eHo, Courtney eMyhr, Elena eBarnaeva, Irina U Agoulnik, Jingbo eXiao, Juan eMarugan, Marc eFerrer, Noel eSouthall, Ross A.D. Bathgate, Xin eHu, Zaohua eHuang +12 morecore +3 more sourcesA vast stem‐progenitor cell pool, richly vascular system, and hybrid ossification drive the daily centimeter‐scale elongation of bony antlers
iMeta, Volume 4, Issue 6, December 2025.Bone growth and regeneration remain major clinical challenges. Deer antlers, the fastest‐growing mammalian bone, regenerate via endochondral ossification and elongate up to 2 cm per day, far surpassing the ~2 cm annual growth of human growth plates. Here, we systematically mapped the cellular landscape of the antler growth center (AGC) using single ...Hengxing Ba, Shidian He, Hai‐Xi Sun, Xin Wang, Hang Zhang, Qiuting Deng, Yue Yuan, Chang Liu, Zhen Wang, Jiping Li, Liuwei Xie, Yujiao Tang, Jimei Wang, Chao Ma, Nan Li, Pengfei Hu, Qianqian Guo, Guokun Zhang, Dawn Elizabeth Coates, Ying Gu, Chuanyu Liu, Datao Wang, Chunyi Li +22 morewiley +1 more sourceThe extracellular matrix and insulin resistance [PDF]
, 2015 The extracellular matrix (ECM) is a highly dynamic compartment that undergoes remodeling as a result of injury and repair. Over the past decade, mounting evidence in humans and rodents suggest that ECM remodeling is associated with diet-induced insulin ...Ashley S. Williams, Bataller, Berria, Bertola, Bisht, Bisht, Bisht, Bonner, Bonner, Brew, Carmiel-Haggai, Catalan, Catalan, Chajara, Cheung, Cheung, Dasu, David H. Wasserman, Day, Delcommenne, Demeulemeester, Derosa, Dixon, Duckworth, Duckworth, El Annabi, Eng, Farrell, Field, Friedman, Friedman, Gardner, Gheyara, Gkretsi, Gressner, Groh, Gullberg, Halberg, Hanks, Harrison, Hill, Hong, Hopps, Huang, Huang, Huber, Hynes, Hynes, Ilic, Inoue, Irwin, Jansson, Jaskiewicz, Jaworski, Jiang, Kang, Kang, Kang, Keophiphath, Khan, Kodama, Kodama, Lewis, Li Kang, Madison, Maher, Martinez-Hernandez, McCuskey, Menghini, Menghini, Moser, Pasarica, Persad, Plows, Postic, Pozzi, Qian, Richardson, Sakai, Schlaepfer, Schuppan, Signorelli, Solomon, Sun, Sun, Tam, Thrailkill, Tinahones, Toole, Troussard, Varma, Vaynberg, Volpes, Wada, Wang, Wang, Watts, White, Williams, Yadav, Zamurs, Zhang, Zong +102 morecore +2 more sourcesThe Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors
British Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,Stephen P. H. Alexander, Anthony P. Davenport, Eamonn Kelly, Alasdair J. Gibb, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Maria Pia Abbracchio, George R. Abraham, Alexander Agoulnik, Wayne Alexander, Khaled Al‐hosaini, Magnus Bäck, Jillian G. Baker, Nicholas M. Barnes, Ross Bathgate, Jean‐Martin Beaulieu, Annette G. Beck‐Sickinger, Maik Behrens, Kirstie A. Bennett, Kenneth E. Bernstein, Bernhard Bettler, Nigel J. M. Birdsall, Victoria A. Blaho, Pascal Bonaventure, Francois Boulay, Corinne Bousquet, Hans Bräuner‐Osborne, Andrew J. Brown, Geoffrey Burnstock, Marta Busnelli, Girolamo Caló, Vanni Caruso, Justo P. Castaño, Kevin J. Catt, Stefania Ceruti, Paul Chazot, Nan Chiang, Bice Chini, Arthur Christopoulos, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H. Clapp, Réjean Couture, Helen M. Cox, Zsolt Csaba, Claes Dahlgren, Frank M. Dautzenberg, Gordon Dent, Steven D. Douglas, Pascal Dournaud, Margarita L. Dubocovich, Satoru Eguchi, Emanuel Escher, Edward J. Filardo, Tung Fong, Huamei Fu Forsman, Marta Fumagalli, Raul R. Gainetdinov, Michael L. Garelja, Marc de Gasparo, Florence Gbahou, Craig Gerard, Marvin Gershengorn, Michelle Glass, David E. Gloriam, Fernand Gobeil, Theodore L. Goodfriend, Cyril Goudet, Lukas Grätz, Karen J. Gregory, Christian Gruber, Andrew L. Gundlach, Jörg Hamann, Julien Hanson, Deborah S. Hartman, Richard L. Hauger, Debbie L. Hay, Akos Heinemann, Laura Heitman, Deron R. Herr, Morley D. Hollenberg, Nicholas D. Holliday, Birgitte Holst, Mastgugu Horiuchi, Daniel Hoyer, László Hunyady, Ahsan Husain, Adriaan P. IJzerman, Tadashi Inagami, Paul A. Insel, Kenneth A. Jacobson, Laura H. Jacobson, Robert T. Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Yasuyuki Kihara, Julia Kinsolving, Takio Kitazawa, Pawel Kozielewicz, Hans‐Jürgen Kreienkamp, Jyrki P. Kukkonen, Luxmichan Laishram, Tobias Langenhan, Christopher J. Langmead, Dan Larhammar, Katie Leach, Davide Lecca, John D. Lee, Susan E. Leeman, Jérôme Leprince, Rob Leurs, Xaria X. Li, Ines Liebscher, Stephen J. Lolait, Amelie Lupp, Robyn Macrae, Janet J. Maguire, Davide Malfacini, Maurice Manning, Davide Marangon, Kirill Martemyanov, Jean Mazella, Craig A. McArdle, Shlomo Melmed, Martin C. Michel, Laurence J. Miller, Vincenzo Mitolo, Bernard Mouillac, Christa E. Müller, Philip M. Murphy, Jean‐Louis Nahon, Richard R. Neubig, Tony Ngo, Xavier Norel, Duuamene Nyimanu, Anne‐Marie O’Carroll, Stefan Offermanns, Maria Antonietta Panaro, Marc Parmentier, Nicole Perry‐Hauser, Roger G. Pertwee, Jean‐Philippe Pin, Eric R. Prossnitz, Helena Chengxue Qin, Mark Quinn, Stefano Raffaele, Rithwik Ramachandran, Manisha Ray, Rainer K. Reinscheid, Alejandro Romeral Buzón, Philippe Rondard, Mette M. Rosenkilde, G. Enrico Rovati, Chiara Ruzza, Gareth J. Sanger, Nicole Scholz, Torsten Schöneberg, Gunnar Schulte, Stefan Schulz, Deborah L. Segaloff, Charles N. Serhan, Arun K. Shukla, Khuraijam Dhanachandra Singh, Craig M. Smith, Nicola J. Smith, Claudia Stäubert, Leigh A. Stoddart, Yukihiko Sugimoto, Roger Summers, Valerie P. Tan, David M. Thal, Walter ( Wally) Thomas, Pieter B. M. W. M. Timmermans, Kalyan Tirupula, Lawrence Toll, Giovanni Tulipano, Hamiyet Unal, Thomas Unger, Celine Valant, Patrick Vanderheyden, David Vaudry, Hubert Vaudry, Joseph G. Verbalis, Jean‐Pierre Vilardaga, Christopher S. Walker, Ji Ming Wang, Donald T. Ward, Hans‐Jürgen Wester, Gary B. Willars, Tom Lloyd Williams, Trent M. Woodruff, Huixian Wu, Cheng Yang, Chengcan Yao, Richard D. Ye, Nathan Zaidman +206 morewiley +1 more source
