Results 91 to 100 of about 14,441 (168)

Metabolic effects of a high-fat diet post-weaning after low maternal dietary folate during pregnancy and lactation [PDF]

, 2014
Scope Investigate the influence of low-folate supply during pregnancy and lactation on obesity and markers of the metabolic syndrome in offspring, and how provision of a high-fat diet post weaning may exacerbate the resultant phenotype.
Ford, Dianne, Langie, Sabine, Manus, Caroline, Mathers, John C., Maxwell, Ross, McKay, Jill, Xie, Long   +6 more
core   +1 more source

In vitro inhibition of Pseudomonas aeruginosa PAO1 biofilm formation by DZ2002 through regulation of extracellular DNA and alginate production

Frontiers in Cellular and Infection Microbiology
IntroductionPseudomonas aeruginosa (P. aeruginosa) is a common pathogen associated with biofilm infections, which can lead to persistent infections. Therefore, there is an urgent need to develop new anti-biofilm drugs.
Jiaze Dai, Wenying Luo, Fei Hu, Si Li
doaj   +1 more source

Identification and Characterization of the Chlamydia trachomatis L2 S-Adenosylmethionine Transporter

mBio, 2011
Methylation is essential to the physiology of all cells, including the obligate intracellular bacterium Chlamydia. Nevertheless, the methylation cycle is under strong reductive evolutionary pressure in Chlamydia.
Rachel Binet, Reinaldo E. Fernandez, Derek J. Fisher, Anthony T. Maurelli   +3 more
doaj   +1 more source

Impact of dietary changes on hepatic homocysteine metabolism in young broilers [PDF]

, 2004
Information regarding the impact of sulfur amino acids (SAA) on hepatic homocysteine (Hcy) flux through the various metabolic pathways competing for Hcy in young broilers is lacking. An experiment was conducted to evaluate the impact of varying levels of
Emmert, Jason L., Ganson, Fauna M., Pillai, Padmakumar   +2 more
core   +2 more sources

Effects of S-Adenosylhomocysteine Hydrolase Downregulation on Wnt Signaling Pathway in SW480 Cells. [PDF]

Int J Mol Sci, 2023
Pavičić I, Rokić F, Vugrek O.
europepmc   +1 more source

Design and Synthesis of a Series of Truncated Neplanocin Fleximers

Molecules, 2014
In an effort to study the effects of flexibility on enzyme recognition and activity, we have developed several different series of flexible nucleoside analogues in which the purine base is split into its respective imidazole and pyrimidine components ...
Sarah C. Zimmermann, Elizaveta O'Neill, Godwin U. Ebiloma, Lynsey J. M. Wallace, Harry P. De Koning, Katherine L. Seley-Radtke   +5 more
doaj   +1 more source

Characterization of human S-adenosyl-homocysteine hydrolase in vitro and identification of its potential inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, 2017
Human S-adenosyl-homocysteine hydrolase (SAHH, E.C.3.3.1.1) has been considered to be an attractive target for the design of medicines to treat human disease, because of its important role in regulating biological methylation reactions to catalyse the ...
Weiwei Hao, Yanhua Li, Qiuli Shan, Tian Han, Wencheng Li, Sheng He, Kongkai Zhu, Yumei Li, Xiaojun Tan, Jinsong Gu   +9 more
doaj   +1 more source

S-Adenosylhomocysteine Is a Useful Metabolic Factor in the Early Prediction of Septic Disease Progression and Death in Critically Ill Patients: A Prospective Cohort Study. [PDF]

Int J Mol Sci, 2023
Centner FS, Schoettler JJ, Brohm K, Mindt S, Jäger E, Hahn B, Fuderer T, Lindner HA, Schneider-Lindner V, Krebs J, Neumaier M, Thiel M.   +11 more
europepmc   +1 more source

Betaine Supplementation Attenuates S-Adenosylhomocysteine Hydrolase-Deficiency-Accelerated Atherosclerosis in Apolipoprotein E-Deficient Mice. [PDF]

Nutrients, 2022
Dai X, Liu S, Cheng L, Huang T, Guo H, Wang D, Xia M, Ling W, Xiao Y.   +8 more
europepmc   +1 more source

S-Adenosylhomocysteine [PDF]

, 2020
openaire   +1 more source