Subcellular one carbon metabolism in cancer, aging and epigenetics
The crosstalk between metabolism and epigenetics is an emerging field that is gaining importance in different areas such as cancer and aging, where changes in metabolism significantly impacts the cellular epigenome, in turn dictating changes in chromatin
Tiziano Bernasocchi +3 more
doaj +1 more source
Assessment of Metabolic Parameters For Autism Spectrum Disorders [PDF]
Autism is a brain development disorder that first appears during infancy or childhood, and generally follows a steady course without remission. Impairments result from maturation-related changes in various systems of the brain.
Ghosh, S +4 more
core
Wumei Pill Ameliorates AOM/DSS-Induced Colitis-Associated Colon Cancer through Inhibition of Inflammation and Oxidative Stress by Regulating S-Adenosylhomocysteine Hydrolase- (AHCY-) Mediated Hedgehog Signaling in Mice. [PDF]
Wang J +11 more
europepmc +1 more source
Effect of folic acid supplementation on the change of plasma S-adenosylhomocysteine level in Chinese hypertensive patients: a randomized, double-blind, controlled clinical trial. [PDF]
Zhang RS +11 more
europepmc +1 more source
Rapid analysis of S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) isotopologues in stable isotope-resolved metabolomics (SIRM) using direct infusion nanoelectrospray ultra-high-resolution Fourier transform mass spectrometry (DI-nESI-UHR-FTMS). [PDF]
Yang J +4 more
europepmc +1 more source
S-Adenosylmethionine Deficiency and Brain Accumulation of S-Adenosylhomocysteine in Thioacetamide-Induced Acute Liver Failure. [PDF]
Czarnecka AM, Hilgier W, Zielińska M.
europepmc +1 more source
Origin and evolution of osmoregulatory mechanisms in blue-green algae (cyanobacteria) as a function of metabolic and structural complexity: Reflections of Precambrian paleobiology [PDF]
Major accomplishments underlying the basic understanding of cyanobacterial resistance to salt tolerance and osmotic stress were made. The methodology proposed included: the tracing of the pathways of formation of osmoregulatory solutes by traditional ...
Pavlicek, Kenneth +2 more
core +1 more source
Efficacy evaluation of the S-adenosylhomocysteine hydrolase inhibitor MSD-914 in rhesus macaques (Macaca Mulatta) challenged with Ebola virus by the intramuscular route. [PDF]
Johnston SC +28 more
europepmc +1 more source
Pyrazole Based Inhibitors against Enzymes of Staphylococcus aureus:A Computational Study [PDF]
Aravindhan, S. +6 more
core +1 more source

