Results 31 to 40 of about 14,441 (168)

Association of serum methionine metabolites with non-alcoholic fatty liver disease: a cross-sectional study

Nutrition & Metabolism, 2022
Background and project Non-alcoholic fatty liver disease (NAFLD) is viewed as the hepatic manifestation of metabolic syndrome. Methionine metabolites have been linked to metabolic syndrome and its related diseases.
Yi Tang, Xu Chen, Qian Chen, Jinghe Xiao, Jiaxin Mi, Qiannan Liu, Yiran You, Yuming Chen, Wenhua Ling   +8 more
doaj   +1 more source

MTHFD1 controls DNA methylation in Arabidopsis. [PDF]

, 2016
DNA methylation is an epigenetic mechanism that has important functions in transcriptional silencing and is associated with repressive histone methylation (H3K9me).
Bischof, Sylvain, Cokus, Shawn J, Díaz de la Garza, Rocío I, Feng, Suhua, Garcia-Salinas, Carolina, Groth, Martin, Hale, Christopher J, Hell, Ruediger, Jacobsen, Steven E, John, Amala, Long, Jeff A, Moissiard, Guillaume, Ramos-Parra, Perla A, Smith, Danielle C, Wang, Haifeng, Wirtz, Markus, Zhai, Jixian   +16 more
core   +2 more sources

Oxidative stress marker aberrations in children with autism spectrum disorder: a systematic review and meta-analysis of 87 studies (N = 9109)

Translational Psychiatry, 2021
There is increasing awareness that oxidative stress may be implicated in the pathophysiology of autism spectrum disorder (ASD). Here we aimed to investigate blood oxidative stress marker profile in ASD children by a meta-analysis.
Lei Chen, Xiao-Jie Shi, Hua Liu, Xiao Mao, Lue-Ning Gui, Hua Wang, Yong Cheng   +6 more
doaj   +1 more source

One-carbon metabolism in cancer [PDF]

, 2017
Cells require one-carbon units for nucleotide synthesis, methylation and reductive metabolism, and these pathways support the high proliferative rate of cancer cells.
AJ MacFarlane, Alice C Newman, AS Tibbetts, B Chaneton, BC Blount, C Commisso, CA Lewis, CF Labuschagne, CF Woeller, D Hanahan, D Hanahan, D Kim, DD Anderson, E Currie, E Mullarky, F Daidone, F Kottakis, G Kikuchi, GM DeNicola, Gregory S. Ducker, GS Ducker, J Liu, J Meiser, J Ye, Jason W. Locasale, JJ Kamphorst, JW Locasale, K Snell, K Snell, K Snell, Katherine R. Mattaini, L Galluzzi, M Goulian, M Jain, M Kulis, Mahya Mehrmohamadi, ME Pacold, Ming Yang, MJ Osborn, ML Rose, ML Rose, OD Maddocks, OD Maddocks, Oliver D K Maddocks, Oliver D. K. Maddocks, PM Ueland, R Possemato, S Farber, S Kit, S Pollari, SJ Mentch, Swetha Bolusani, T Shlomi, WC Zhang, Y Fu, Z Ser   +55 more
core   +1 more source

Effects of Partially Defatted Hermetia illucens Meal in Rainbow Trout Diet on Hepatic Methionine Metabolism

Animals, 2020
This study investigated, for the first time, the effects of replacement of fishmeal (FM) with insect meal from Hermetia illucens (HI) on the transcript levels of three genes involved in methionine (Met) metabolism in rainbow trout (Oncorhynchus mykiss ...
Genciana Terova, Chiara Ceccotti, Chiara Ascione, Laura Gasco, Simona Rimoldi   +4 more
doaj   +1 more source

Elevated Levels of Methylmalonate and Homocysteine in Parkinson's Disease, Progressive Supranuclear Palsy and Amyotrophic Lateral Sclerosis [PDF]

, 2010
Background/Aims: Increasing evidence suggests that elevated levels of homocysteine (Hcy) and methylmalonate (MMA) may be involved in the pathogenesis of neurodegenerative diseases. Methods: The urine levels of MMA and serum levels of Hcy as well as folic
Bötzel, Kai, Giese, Armin, Levin, Johannes, Lorenzl, Stefan, Vogeser, Michael   +4 more
core   +1 more source

Blockade of the trans-sulfuration pathway in acute pancreatitis due to nitration of cystathionine β-synthase

Redox Biology, 2020
Acute pancreatitis is an inflammatory process of the pancreatic gland that may lead to dysregulation of the trans-sulfuration pathway. The aims of this work were firstly to study the methionine cycle as well as the trans-sulfuration pathway using ...
Sergio Rius-Pérez, Salvador Pérez, Isabel Torres-Cuevas, Pablo Martí-Andrés, Raquel Taléns-Visconti, Alberto Paradela, Laura Guerrero, Luis Franco, Gerardo López-Rodas, Luis Torres, Fernando Corrales, Juan Sastre   +11 more
doaj   +1 more source

Nitric oxide modulates folate-mediated one-carbon metabolism and mitochondrial energy levels of peaches during cold storage

Frontiers in Nutrition, 2023
Folate-mediated one-carbon metabolism (FOCM) is closely associated with postharvest preservation. This study investigated the effects of exogenous nitric oxide (NO) on FOCM, storage quality, energy metabolism, and mitochondrial membrane integrity in cold-
Zhifeng Yang, Shuhua Zhu, Shuhua Zhu, Xiaoyu Wang, Changbao Chen, Dandan Huang, Jianrong Feng   +6 more
doaj   +1 more source

LC-MS proteomics analysis of the iInsulin/IGF-1-deficient Caenorhabditis elegans daf-2(e1370) mutant reveals extensive restructuring of intermediary metabolism [PDF]

, 2014
The insulin/IGF-1 receptor is a major known determinant of dauer formation, stress resistance, longevity, and metabolism in Caenorhabditis elegans. In the past, whole-genome transcript profiling was used extensively to study differential gene expression ...
Braeckman, Bart, Brewer, Heather M, Camp, David G, II, Depuydt, Geert, Petyuk, Vladislav A, Smith, Richard D, Smolders, Arne, Xie, Fang   +7 more
core   +2 more sources

Homocysteine, S-adenosylmethionine and S-adenosylhomocysteine are associated with retinal microvascular abnormalities: the Hoorn Study [PDF]

, 2007
The aim of the present study was to investigate the relationship between homocysteine and homocysteine metabolism components and retinal microvascular disorders in subjects with and without Type 2 diabetes.
Aldington, Becker, Beks, Bettine C.P. Polak, Cahill, Castro, Chobanian, Coen D.A. Stehouwer, Cornelis Jakobs, De Vriese, Fassbender, Finkelstein, Finkelstein, Giel Nijpels, Henry, Henry, Hofmann, Homocysteine Studies Collaboration, Hoogeveen, Hoogeveen, Hoogeveen, Hoogeveen, Hubbard, Ikram, Jacqueline M. Dekker, Jager, Jager, James, Kerins, Knudtson, Kumagai, Leeming, Leung, Lex M. Bouter, Loehrer, Loehrer, Loria, Manon V. Van Hecke, Moat, Mooy, Parr, Parr, Robinson, Rob J. Heine, Ronald P. Stolk, Shipchandler, Smulders, Spijkerman, Stam, Struys, Tom Teerlink, Ubbink, Vaccaro, van Guldener, van Leiden, Vermeulen, Wang, Welch, Wirta, World Health Organization   +59 more
core   +10 more sources