Results 41 to 50 of about 15,817,770 (195)
Functional and Pathological Roles of AHCY
Frontiers in Cell and Developmental Biology, 2021 Adenosylhomocysteinase (AHCY) is a unique enzyme and one of the most conserved proteins in living organisms. AHCY catalyzes the reversible break of S-adenosylhomocysteine (SAH), the by-product and a potent inhibitor of methyltransferases activity.
Pedro Vizán +4 more
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S-adenosylhomocysteine metabolism in Streptomyces flocculus [PDF]
Journal of Bacteriology, 1988 S-Adenosylhomocysteine metabolism was studied in cell extracts of streptonigrin-producing Streptomyces flocculus. The major route of metabolism was found to be deamination to form S-inosylhomocysteine. The metabolite was purified by high-performance liquid chromatography and identified by its UV and nuclear magnetic resonance spectra and by its ...
M K, Speedie, J J, Zulty, P, Brothers
openaire +2 more sources
Regulation of homocysteine metabolism by Mycobacterium tuberculosis S-adenosylhomocysteine hydrolase. [PDF]
Sci Rep, 2013 Mycobacterium tuberculosis modulates expression of various metabolism-related genes to adapt in the adverse host environment. The gene coding for M. tuberculosis S-adenosylhomocysteine hydrolase (Mtb-SahH) is essential for optimal growth and the protein ...
Singhal A +9 more
europepmc +3 more sources
Inhibition of Dam by S-adenosylhomocysteine. [PDF]
, 2013 (A) A double reciprocal plot of methylation rate against AdoMet concentration. S-adenosylhomocysteine concentrations were; 0 (•), 5 (○), 10 (▾), 15 (Δ), 20 (▪), 30 (□) and 40 (♦) µM.
Rick W. Titball (78352) +5 more
core +1 more source
Nutrition & Metabolism, 2022 Background and project Non-alcoholic fatty liver disease (NAFLD) is viewed as the hepatic manifestation of metabolic syndrome. Methionine metabolites have been linked to metabolic syndrome and its related diseases.
Yi Tang +8 more
doaj +1 more source
Homocysteine-induced endothelial cell adhesion is related to adenosine lowering and is not mediated by S-adenosylhomocysteine [PDF]
, 2007 Hyperhomocysteinemia is a cardiovascular risk factor and may contribute to the pathogenesis of atherosclerosis by altering endothelial functions. The mechanism of homocysteine-induced cell adhesion has been here investigated using EA.hy 926 cells ...
Cacciapuoti, Giovanna +4 more
core +3 more sources
Translational Psychiatry, 2021 There is increasing awareness that oxidative stress may be implicated in the pathophysiology of autism spectrum disorder (ASD). Here we aimed to investigate blood oxidative stress marker profile in ASD children by a meta-analysis.
Lei Chen +6 more
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DETERMINATION OF S-ADENOSYLHOMOCYSTEINE IN TISSUES FOLLOWING PHARMACOLOGICAL INHIBITION OF S-ADENOSYLHOMOCYSTEINE CATABOLISM: 84 [PDF]
Pediatric Research, 1985 The amount of S-adenosylhomocysteine in liver increases 2 to 3 fold during the first minute following death of the animal (Hoffman, D.R. et al. (1979) Can. J. Biochem. 57, 56-65), and postmortem increase in AdoHcy should be avoided when determining the physiological level of AdoHcy.
Svein Helland, Per M Ueland
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The Analysis of S-Adenosylmethionine and S-Adenosylhomocysteine in Normal and Neoplastic Cells [PDF]
, 1980 Altered patterns of methylation have been shown in both ribosomal and transfer RNA isolated from cancer cells. In contrast to the elevated activity of the methyltransferases responsible for this modification, hypomethylation appears as a general ...
Godburn, Kathryn Elizabeth
core +2 more sources
Animals, 2020 This study investigated, for the first time, the effects of replacement of fishmeal (FM) with insect meal from Hermetia illucens (HI) on the transcript levels of three genes involved in methionine (Met) metabolism in rainbow trout (Oncorhynchus mykiss ...
Genciana Terova +4 more
doaj +1 more source