Results 61 to 70 of about 14,441 (168)

Dietary protein restriction regulates skeletal muscle fiber metabolic characteristics associated with the FGF21-ERK1/2 pathway

open access: yesiScience
Summary: Under conditions of dietary amino acid balance, decreasing the dietary crude protein (CP) level in pigs has a beneficial effect on meat quality.
Shuo Li   +6 more
doaj   +1 more source

Metabolite-dependent regulation of gene expression in trypanosoma brucei [PDF]

open access: yes, 2013
Mechanisms regulating gene expression in trypanosomatid protozoa differ significantly from those in other eukaryotes. Transcription of the genome appears to be more or less constitutive with the polyadenylation and trans-splicing of large polycistronic ...
Archer   +34 more
core   +1 more source

DYRK1A, a novel determinant of the methionine-homocysteine cycle in different mouse models overexpressing this Down-syndrome-associated kinase.

open access: yesPLoS ONE, 2009
BackgroundHyperhomocysteinemia, characterized by increased plasma homocysteine level, is associated with an increased risk of atherosclerosis. On the contrary, patients with Down syndrome appear to be protected from the development of atherosclerosis. We
Christophe Noll   +15 more
doaj   +1 more source

Sonophoresis efficiency: consequences of methyl donors supplementation at early developmental stage in gilthead seabream (Sparus aurata). Effects on growth, nutrient metabolism, egg and larval quality, and methylation patterns of larvae and juvenile fish [PDF]

open access: yes, 2016
Dissertação de mestrado, Aquacultura e Pescas, Faculdade de Ciências e Tecnologia, Universidade do Algarve, 2016It is essential that the vegetable ingredients that will be use in Aquaculture feeds can maintain the growth parameters in fish when compared
Lopes, André Casimiro Carvalho
core  

Aspectos relevantes de la S-adenosilhomocisteína hidrolasa relacionados con el metabolismo de la S-adenosilhomocisteína Relevant aspects of S-adenosylhomocysteine hydrolase related to the metabolism of S-adenosylhomocysteine

open access: yesRevista Cubana de Investigaciones Biomédicas, 2006
Se realizó una revisión de la S-adenosil metionina, considerado como el donante fundamental de grupos metilo en el organismo. Por una reacción de transmetilación es obtenida la S-adenosil homocisteína, que es un potente inhibidor de transmetilasas ...
Yelamy Travieso González   +3 more
doaj  

Magnesium ions mediate ligand binding and conformational transition of the SAM/SAH riboswitch

open access: yesCommunications Biology, 2023
The SAM/SAH riboswitch binds S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) with similar affinities. Mg2+ is generally known to stabilize RNA structures by neutralizing phosphates, but how it contributes to ligand binding and conformational ...
Guodong Hu, Huan-Xiang Zhou
doaj   +1 more source

Serum S-adenosylmethionine, but not methionine, increases in response to overfeeding in humans [PDF]

open access: yes, 2016
Background: Plasma concentration of the methyl donor S-adenosylmethionine (SAM) is linearly associated with body mass index (BMI) and fat mass. As SAM is a high-energy compound and a sensor of cellular nutrient status, we hypothesized that SAM would ...
Elshorbagy, A.   +4 more
core   +1 more source

Copper ions inactivate S-adenosylhomocysteine hydrolase

open access: yesChinese Science Bulletin, 2002
S-adenosylhomocysteine (AdoHcy) hydrolase is an enzyme that regulates biomethylation and some other physiological processes. Recombinant AdoHcy hydrolase was overexpressed inE. coli JM109 and purified with ion exchange and gel filtration chromatographies.
Jiejin Chen   +3 more
openaire   +2 more sources

Inhibition of sterol transmethylation by S-adenosylhomocysteine analogs [PDF]

open access: yesJournal of Bacteriology, 1981
Structural analogs of S-adenosylhomocysteine were tested in vitro for inhibition of the yeast S-adenosylmethionine:delta 24-sterol-C-methyltransferase enzyme. A wide inhibitory range by these compounds was observed, suggesting which structural features of the parent compound are important for binding to the enzyme.
M T, McCammon, L W, Parks
openaire   +2 more sources

Molecular responses of mouse macrophages to copper and copper oxide nanoparticles inferred from proteomic analyses [PDF]

open access: yes, 2013
The molecular responses of macrophages to copper-based nanoparticles have been investigated via a combination of proteomic and biochemical approaches, using the RAW264.7 cell line as a model.
Aude-Garcia, Catherine   +12 more
core   +5 more sources

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