Results 41 to 50 of about 4,880 (161)

Characterization of plant glutamine synthetase S-nitrosation

Nitric Oxide, 2019
The identification of S-nitrosated substrates and their target cysteine residues is a crucial step to understand the signaling functions of nitric oxide (NO) inside the cells. Here, we show that the key nitrogen metabolic enzyme glutamine synthetase (GS) is a S-nitrosation target in Medicago truncatula and characterize the molecular determinants and ...
Liliana S, Silva, Mariana Q, Alves, Ana R, Seabra, Helena G, Carvalho   +3 more
openaire   +2 more sources

Decreased S-nitrosation of peptide thiols in the membrane interior [PDF]

Free Radical Biology and Medicine, 2009
It has been proposed that autoxidation of nitric oxide (()NO) stimulates S-nitrosation of thiols located in the hydrophobic milieu. We tested whether thiols located in hydrophobic membranes undergo enhanced S-nitrosation in the presence of ()NO/O(2). The transmembrane cysteinyl peptides C(4) (AcNH-KKACALA(LA)(6)KK-CONH(2)) and C(8) (AcNH-KKALALACALA(LA)
Hao, Zhang, Christopher, Andrekopoulos, Yingkai, Xu, Joy, Joseph, Neil, Hogg, Jimmy, Feix, B, Kalyanaraman   +6 more
openaire   +2 more sources

A clickable probe for versatile characterization of S-nitrosothiols

Redox Biology, 2020
S-nitrosation of cysteine thiols (SNOs), commonly referred to as S-nitrosylation, is a cysteine oxoform that plays an important role in cellular signaling and impacts protein function and stability.
Jenna L. Clements, Franziska Pohl, Pandi Muthupandi, Stephen C. Rogers, Jack Mao, Allan Doctor, Vladimir B. Birman, Jason M. Held   +7 more
doaj   +1 more source

S-nitrosation of proteins [PDF]

Tissue Barriers, 2013
Nitric oxide (NO) is a key factor in inflammation as it regulates microvascular permeability, leukocyte adhesion and wound healing. This mini-review addresses mainly spatial and temporal requirements of NO regulatory mechanisms, with special emphasis on S-nitrosation. Endothelial nitric oxide synthase (eNOS)-derived NO induces S-nitrosation of p120 and
Sánchez, Fabiola A., Ehrenfeld, Ingrid P., Durán, Walter N.   +2 more
openaire   +2 more sources

S-Nitrosation and Ubiquitin-Proteasome System Interplay in Neuromuscular Disorders

International Journal of Cell Biology, 2014
Protein S-nitrosation is deemed as a prototype of posttranslational modifications governing cell signaling. It takes place on specific cysteine residues that covalently incorporate a nitric oxide (NO) moiety to form S-nitrosothiol derivatives and depends
Salvatore Rizza, Costanza Montagna, Giuseppina Di Giacomo, Claudia Cirotti, Giuseppe Filomeni   +4 more
doaj   +1 more source

Atomic‐Scale Understanding of Selectivity Control in Nitrate Reduction on Cu(100) Under Acidic and Alkaline Conditions

Angewandte Chemie, Volume 138, Issue 23, 1 June 2026.
A combination of ab initio molecular dynamics simulations and density functional theory calculations clarifies the pH‐dependent origin of the selectivity of nitrate reduction on Cu(100). ABSTRACT We investigate the nitrate reduction reaction (NO3 RR) on the Cu(100) surface using grand‐canonical density functional theory (GC‐DFT) under constant ...
Ebrahim Tayyebi, Kai S. Exner
wiley   +2 more sources

Nitrite-mediated reduction of macrophage NADPH oxidase activity is dependent on xanthine oxidoreductase-derived nitric oxide but independent of S-nitrosation

Redox Biology, 2016
Background: Inorganic nitrite has shown beneficial effects in cardiovascular and metabolic diseases partly via attenuation of NADPH-oxidase (NOX)-mediated oxidative stress. However, the exact mechanisms are still unclear. Here we investigated the role of
Christa Zollbrecht, A. Erik G. Persson, Jon O. Lundberg, Eddie Weitzberg, Mattias Carlström   +4 more
doaj   +1 more source

The Synthesis Use of a Difluorinated Amino‐Benzo‐Cinnoline Dyes (ABCDyes) Enables Fine Tuning of Emission Through Double SNAr Late‐Stage Functionalization

European Journal of Organic Chemistry, EarlyView.
An efficient synthesis of difluorinated amino‐benzo‐cinnoline dyes (ABCDyes) is reported. Their use for the late‐stage introduction of internal dinucleophilic species through a double SNAr reaction enables straightforward access to previously unexplored ABCDye analogs displaying tunable emission ranging from green to red.
Mélina Fabe, Narjis Ouazzani, Max Coehlo, Arnaud Chevalier   +3 more
wiley   +1 more source

Navigating Nitration Chemistry: A Practical Guide to Reagents, Mechanisms, and Selectivity

Angewandte Chemie, Volume 138, Issue 20, 11 May 2026.
This review highlights key contributions of modern nitration chemistry, emphasizing sustainable mechanistic platforms and comparing the performance of both organic and inorganic reagents across aromatic, ipso‐, olefin, alkyne, and heteroatom nitration. It provides the community with a clearer, unified perspective on current advances and facilitates the
Harry Lecomte, Anthony J. Fernandes, Dmitry Katayev   +2 more
wiley   +2 more sources

Sweet Pepper (Capsicum annuum L.) Fruits Contain an Atypical Peroxisomal Catalase That Is Modulated by Reactive Oxygen and Nitrogen Species

Antioxidants, 2019
During the ripening of sweet pepper (Capsicum annuum L.) fruits, in a genetically controlled scenario, enormous metabolic changes occur that affect the physiology of most cell compartments.
Marta Rodríguez-Ruiz, Salvador González-Gordo, Amanda Cañas, María Jesús Campos, Alberto Paradela, Francisco J. Corpas, José M. Palma   +6 more
doaj   +1 more source