Results 81 to 90 of about 4,880 (161)
Peroxiredoxins (Prxs; EC 1.11.1.15) are a group of thiol peroxidases that catalyze the detoxification of H2O2 and other organic hydroperoxides. The ripening of pepper (Capsicum annuum L.) fruit involves significant phenotypic, physiological, and ...
Fátima Ramírez-Mellado +3 more
doaj +1 more source
S-nitrosation in endothelium: different outcomes of NRF2 and GSNOR loss
Cardiovascular diseases are a major global health burden, and that is largely caused by premature aging of endothelial cells (ECs). Therefore, understanding of molecular mechanisms of EC aging is central to establishing novel therapeutic approaches. We have previously found that cells devoid of the transcription factor NRF2 are prematurely aged and ...
Aleksandra Kopacz +8 more
openaire +3 more sources
Nitric oxide (NO) is a key signaling molecule in all kingdoms. In plants, NO is involved in the regulation of various processes of growth and development as well as biotic and abiotic stress response.
Alexandra Ageeva-Kieferle +2 more
doaj +1 more source
Modulation of S‐nitrosation by thioredoxin regulates endothelial permeability
Protein S‐nitrosation has emerged recently as a mechanism to regulate cell function. We tested the hypothesis that cytosolic thioredoxin (Trx1) – thioredoxin reductase (TrxR1) system contributes to the control of endothelial permeability. In human microvascular endothelial cells (HMVEC) of dermal origin, we used PAF‐stimulated hyperpermeability and ...
Patricio E. Mujica +2 more
openaire +1 more source
NO- and S-nitrosothiols-dependent relaxation in large and small resistance blood vessels
Nitric oxide (NO) has long been viewed as the principal endothelium-derived vasodilator through activation of soluble guanylyl cyclase (GC1) and cGMP-dependent signaling in vascular smooth muscle.
Mauricio A. Lillo, Annie Beuve
doaj +1 more source
Nitric oxide delivery and heme-assisted S-nitrosation by the bedbug nitrophorin. [PDF]
Badgandi HB, Weichsel A, Montfort WR.
europepmc +1 more source
S-nitrosation of proteins by N-methyl-N-nitrosoanilines
Abstract Substituted N-methyl-N-nitrosoanilines are found to function as stable, potent, nitrosating agents for S-nitrosation and inactivation of cysteine proteases such as papain, bromelain and aldehyde dehydrogenase under physiological conditions in a time and concentration dependent manner.
Zhengmao Guo +5 more
openaire +1 more source
Corrigendum to "Downregulation of Thioredoxin-1-dependent CD95 S-nitrosation by Sorafenib reduces liver cancer" [Redox Biol. 34 (2020) 101528]. [PDF]
González R +14 more
europepmc +1 more source
Nitric oxide (NO) modulates low temperature-stress signaling via S-nitrosation, a NO PTM, inducing ethylene biosynthesis inhibition leading to enhanced post-harvest shelf-life of agricultural produce. [PDF]
Sougrakpam Y, Babuta P, Deswal R.
europepmc +1 more source
Post-translational modification is a prerequisite for the functions of intracellular proteins. Thiol-based oxidative post-translational modifications (OxiPTMs) mainly include S-sulfenylation, S-nitrosation, persulfidation, and S-glutathionylation ...
Hongxin Li +7 more
doaj +1 more source

