Results 141 to 150 of about 22,830,963 (211)
PalmPred: an SVM based palmitoylation prediction method using sequence profile information.
PLoS ONE, 2014 Protein palmitoylation is the covalent attachment of the 16-carbon fatty acid palmitate to a cysteine residue. It is the most common acylation of protein and occurs only in eukaryotes.
Bandana Kumari +2 more
doaj +1 more source
Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.NINJ1 mediates PMR in cardiovascular cell death, releasing DAMPs that amplify vascular inflammation. Dual NINJ1 paradox: membrane‐bound form drives endothelial NF‐κB/CXCL‐8 inflammation while soluble form provides atheroprotection. Pericyte NINJ1 regulates the critical balance between angiogenic sprouting and vessel maturation in ischaemic tissues ...
Muhammad Mamunur Rashid Mahib
wiley +1 more source
Mass spectrometry analysis of protein/peptide S-palmitoylation [PDF]
, 2016 The dynamic S-palmitoylation regulates many intracellular events, including protein trafficking, anchoring, targeting, and protein-protein interactions.
Ji, Yuhuan
core +1 more source
Journal of Extracellular Vesicles, Volume 15, Issue 3, March 2026.We present a novel live‐cell imaging assay for detection of extracellular vesicle (EV)‐binding, ‐uptake, and ‐fusion in time and space. Using EVs carrying the fusogen VSV‐G, we demonstrate real‐time imaging of EV‐fusion, quantification of fusion kinetics and efficiency, and subcellular localization of fusion events.
Jasper van den Ende +5 more
wiley +1 more source
Journal of Extracellular Vesicles, Volume 15, Issue 3, March 2026.ABSTRACT Hepatocellular carcinoma (HCC) typically emerges in a fibrotic premalignant liver milieu, and hepatic stellate cells (HSCs) represent the predominant cell subtype implicated in hepatic fibrosis. The crosstalk between HCC cells and HSCs has been demonstrated to affect HCC progression.
Qi‐tao Chen +10 more
wiley +1 more source
The NLRP3 Inflammasome: Mechanisms of Activation, Regulation, and Therapeutic Opportunities
MedComm, Volume 7, Issue 3, March 2026.Diverse diseases converge on NLRP3. We depict a discovery‐to‐clinic track: high‐throughput/phenotypic screens, structure‐guided design, and modality innovation (allosteric inhibitors, interface blockers, degraders) deliver third‐generation, disease‐tailored NLRP3 control.
Chan Zou +5 more
wiley +1 more source
cGMP signalling regulates S-palmitoylation in sensory neurons
, 2017 During the development of the vertebrate nervous system, neurons from the central and the peripheral nervous systems generate an axon which navigates through the tissues. In many cases it might innervate multiple target regions by forming branches and by this build a complex and well-ordered network.
openaire +1 more source
RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications
MedComm – Oncology, Volume 5, Issue 1, March 2026.Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang +6 more
wiley +1 more source
Protein S-palmitoylation in synaptic plasticity
Neuroscience Applied, 2023 A. Pytyś +4 more
openaire +1 more source
Prokaryotic PfaB is a terminal acyltransferase that determines the final PUFA product
Protein Science, Volume 35, Issue 3, March 2026.Abstract Omega‐3 polyunsaturated fatty acids (PUFAs) are essential for human health due to their numerous beneficial biological properties. These compounds are synthesized in marine bacteria and eukaryotic microalgae by PUFA megasynthases (Pfas), which are evolutionarily related to fatty acid synthases (FAS) and polyketide synthases (PKS). In FAS, PKS,
Nahuel Lofeudo +5 more
wiley +1 more source