Results 201 to 210 of about 38,415 (238)

A Case of Primary Intramedullary Infantile Fibrosarcoma With an RBPMS::NTRK3 Fusion and Response to Larotrectinib

open access: yesNeuropathology and Applied Neurobiology, Volume 52, Issue 5, October 2026.
We report a case of primary intramedullary infantile fibrosarcoma (IFS) in a 4‐week‐old infant with rapidly progressive cervical myelopathy. Histology showed a spindle cell tumour with diffuse S100 and pan‐TRK expression. RNA sequencing identified an RBPMS::NTRK3 fusion.
Mégane Le Quang   +8 more
wiley   +1 more source

Skin Commensal Microbiota Does Not Influence the Clinical Course of Dermatophyte Infection in Persian Cats

open access: yesVeterinary Dermatology, Volume 37, Issue 5, Page 700-712, October 2026.
Dermatophytes can be isolated from both symptomatic and asymptomatic cats, yet the role of skin commensals in modulating disease expression remains unclear. This study investigates whether microbial skin communities influence the clinical presentation (symptomatic or asymptomatic) of dermatophyte infection in Persian cats.
Aline E. Santana   +2 more
wiley   +1 more source

ASXL1 in proinflammatory macrophages attenuates inflammatory activation and macrophage‐mediated renal tubular epithelial cell damage in acute kidney injury

open access: yesPhysiological Reports, Volume 14, Issue 19, October 2026.
ASXL1 in inflammatory macrophages attenuates renal tubular cell damage through coordinated histone modification of H3K27me3 and H3K4me3 in acute kidney injury. Abstract Macrophages are major contributors to inflammatory responses in acute kidney injury (AKI) and rapidly alter their gene expression through epigenetic regulation.
Yoshiyasu Ogura   +3 more
wiley   +1 more source

S100A1 Promotes MDM2‐Mediated KLF15 Ubiquitination to Regulate ID1‐Driven Tubular Injury in Diabetic Kidney Disease

open access: yesThe FASEB Journal, Volume 40, Issue 18, 30 September 2026.
High glucose upregulates S100A1, enhancing MDM2–KLF15 interaction and K48‐linked ubiquitination of KLF15. Degradation of KLF15 relieves ID1 repression, promoting ID1 upregulation, inflammation, fibrosis, tubular injury, and DKD progression. ABSTRACT Diabetic kidney disease (DKD) is the leading cause of end‐stage renal disease globally.
Zhitao Zeng   +9 more
wiley   +1 more source

Peptidthioester und Peptidtriazolderivate durch Duale Modifikation von Peptidthiosulfonaten auf dem Harz

open access: yesAngewandte Chemie, Volume 138, Issue 38, 14 September 2026.
Es wird eine Strategie zur dualen Modifikation von Peptiden auf der Festphase vorgestellt, die die S‐Alkinylierung von Peptidthiosulfonaten und eine regioselektive, iridiumkatalysierte Azid‐Thioalkin‐Zykloaddition umfasst. Dieses Verfahren ermöglicht zuverlässig den Zugang zu Peptiden mit komplexen, nicht‐kanonischen Modifikationen und ist mit ...
Marius Werner   +5 more
wiley   +1 more source

Peptide Thioester and Triazole Derivatives Through On‐Resin Dual‐Modification of Peptide Thiosulfonates

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 38, 14 September 2026.
An on‐resin dual‐modification strategy for peptides is presented, comprising S‐alkynylation of peptide thiosulfonates and regioselective iridium‐catalyzed azide–thioalkyne cycloaddition. This method reliably provides access to peptides with intricate non‐canonical modifications, being compatible with complex peptides, alkynes and azides.
Marius Werner   +5 more
wiley   +1 more source

Canine Tear Proteomics: A New Frontier in Veterinary Ophthalmology. [PDF]

open access: yesVet Ophthalmol
D'Agostino AL   +5 more
europepmc   +1 more source

S100 Proteins in Cancer

open access: yesAdvances in Clinical Medicine
openaire   +1 more source
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S100 proteins in atherosclerosis

Clinica Chimica Acta, 2020
Atherosclerosis is an arterial disease associated with dyslipidemia, abnormal arterial calcification and oxidative stress. It has been shown that a continued chronic inflammatory state of the arterial wall contributes to the development of atherosclerosis.
Xuan Xiao   +7 more
openaire   +2 more sources

A review of the S100 proteins in cancer

European Journal of Surgical Oncology, 2008
In the quest to reduce mortality and morbidity from cancer, there is continued effort to identify novel biomarkers to aid in the early detection and the accurate prediction of tumour behaviour. One group of proteins that is emerging as a potentially important group of markers in multiple tumour types is the S100 family.
J L Jones, J L Jones
exaly   +3 more sources

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