Results 211 to 220 of about 6,556,654 (241)
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Tissue distribution of rat S100 alpha and S100 beta and S100-binding proteins
American Journal of Physiology-Cell Physiology, 1987To understand the physiological role of the calcium-binding proteins S100 alpha and S100 beta, it is necessary to determine the distribution of these proteins and detect their intracellular targets in various tissues. The distribution of immunoreactive S100 alpha and S100 beta in various rat tissues was examined by radioimmunoassay.
D B, Zimmer, L J, Van Eldik
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Indian Journal of Cancer, 2014
S100 protein is the largest subtribe in calcium binding protein family. According to recent researches, abnormal expression of S100 protein is often related to tumor, including breast tumor. Breast tumor is the most common malignant disease in female with high mortality mainly due to metastasis.
F, Li, X, Men, W, Zhang
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S100 protein is the largest subtribe in calcium binding protein family. According to recent researches, abnormal expression of S100 protein is often related to tumor, including breast tumor. Breast tumor is the most common malignant disease in female with high mortality mainly due to metastasis.
F, Li, X, Men, W, Zhang
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Clinical Immunology, 2020
Up to 80% of juvenile-onset systemic lupus erythematosus (jSLE) patients develop lupus nephritis (LN) that affects treatment and prognosis. Easily accessible biomarkers do not exist to reliably diagnose LN, leaving kidney biopsies as the gold-standard ...
S. Donohue +9 more
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Up to 80% of juvenile-onset systemic lupus erythematosus (jSLE) patients develop lupus nephritis (LN) that affects treatment and prognosis. Easily accessible biomarkers do not exist to reliably diagnose LN, leaving kidney biopsies as the gold-standard ...
S. Donohue +9 more
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S100 Proteins in Autoinflammation
Textbook of Autoinflammation, 2019Among the putative markers for autoinflammatory diseases, studies on phagocyte-derived S100 proteins (S100A8/A9, S100A12: calgranulins) are the most advanced to date. Translational studies have suggested an important role for these danger-associated molecular pattern (DAMP) molecules as robust inflammation biomarkers.
D. Holzinger, C. Kessel, D. Foell
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S100 proteins and the skin: a review
Journal of the European Academy of Dermatology and Venereology, 2013AbstractThe structurally related, low‐molecular weight S100 proteins constitute a family of proteins that possess a common basic structure allowing them to carry out a range of intracellular and extracellular functions. Unifying intracellular functions relate to regulation of proliferation, energy metabolism, calcium homeostasis, enzyme activities ...
A, Halawi, O, Abbas, M, Mahalingam
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A review of the S100 proteins in cancer
European Journal of Surgical Oncology (EJSO), 2008In the quest to reduce mortality and morbidity from cancer, there is continued effort to identify novel biomarkers to aid in the early detection and the accurate prediction of tumour behaviour. One group of proteins that is emerging as a potentially important group of markers in multiple tumour types is the S100 family.
I, Salama +3 more
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S100 protein and down syndrome
BioEssays, 1990AbstractS100 protein is a low molecular weight calcium‐binding protein widely distributed in the central nervous system of vertebrates. Recent evidence suggests that S100 protein may play a role in the regulation of glial proliferation and neuronal differentiation. The gene for S100 protein has been mapped to the 21q22 region, a chromosomal locus whose
A, Marks, R, Allore
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Intrinsic disorder in S100 proteins
Molecular BioSystems, 2011Abstract Although the members of the largest subfamily of the EF-hand proteins, S100 proteins, are evolutionarily young, their functional diversity is extremely broad, partly due to their ability to adapt to various targets. This feature is a hallmark of intrinsically disordered proteins (IDPs), but none of the S100 proteins are ...
Sergei E, Permyakov +5 more
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Bovine Brain S100 Proteins: Separation and Characterization of a New S100 Protein Species
Journal of Neurochemistry, 1983Abstract: Three S100 protein species (S100a, S100b, S100a′) have been purified from bovine brain using a modification of standard preparative methods. A higher yield for each protein was obtained at the last separation step. Characterization by urea/sodium dodecyl sulfate/polyacrylamide gel electrophoresis, UV absorption spectra, and fluorescence ...
J, Baudier, P, Mandel, D, Gérard
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1996
Abstract Members of the 5100 Ca2•-binding protein family are typically small, acidic proteins containing two Ca2•-binding sites. It has been suggested, that they are associated with cell cycle progression, differentiation, metabolism, and the generation of neoplastic cells. Each member of the 5100 protein family shows a unique spatial
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Abstract Members of the 5100 Ca2•-binding protein family are typically small, acidic proteins containing two Ca2•-binding sites. It has been suggested, that they are associated with cell cycle progression, differentiation, metabolism, and the generation of neoplastic cells. Each member of the 5100 protein family shows a unique spatial
openaire +1 more source