Results 181 to 190 of about 6,556,654 (241)
EV‐SPEC: Decoding the Spatial Proteomic Signature of the Extracellular Vesicle Corona
This study introduces ‘EV‑SPEC’, a spatial proteomics method using TurboID fused to the transmembrane protein CD63 to map the protein corona of extracellular vesicles (EVs) without physical isolation. We show that EV‐SPEC identifies the protein‐protein interaction footprint of serum proteins, similar to those typically found on synthetic nanoparticles,
Camille Menaceur Vandenbroucke +2 more
wiley +1 more source
Changes in S100 Proteins Identified in Healthy Skin following Electrical Stimulation: Relevance for Wound Healing. [PDF]
Lallyett C +6 more
europepmc +1 more source
American Journal of Hematology, Volume 101, Issue 6, Page 1269-1272, June 2026.
Stephanie Quon +5 more
wiley +1 more source
Urea provides an important nitrogen source for microbial populations in an ultraoligotrophic sea
Urea is an organic nitrogen (N) compound directly utilized by both heterotrophic prokaryotes and some photoautotrophs. Reports of either ambient urea concentrations or urea uptake rates from the ultraoligotrophic eastern Mediterranean Sea are lacking. We investigated urea distribution and uptake in the upper water column in the Levantine basin during ...
Alon Blachinsky +7 more
wiley +1 more source
Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu +9 more
wiley +1 more source
Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley +1 more source
Abstract Ceramide deficiency in the stratum corneum (SC) is a key etiological factor in atopic dermatitis (AD). To clarify the direct role of SC ceramide depletion in impairing SC barrier and water‐holding functions and in initiating AD‐like skin symptoms and disease‐specific molecular alterations, we generated Tg mice overexpressing a mutant form of ...
Mariko Takada +8 more
wiley +1 more source

