In vitro assessment of antimicrobial, antioxidant, and cytotoxic properties of Saccharin-Tetrazolyl and-Thiadiazolyl derivatives: the simple dependence of the pH value on antimicrobial activity [PDF]
, 2019 The antimicrobial, antioxidant, and cytotoxic activities of a series of saccharin-tetrazolyl and -thiadiazolyl analogs were examined. The assessment of the antimicrobial properties of the referred-to molecules was completed through an evaluation of ...
Andrade, Joana M. +9 more
core +1 more source
Does low-energy sweetener consumption affect energy intake and body weight? A systematic review, including meta-analyses, of the evidence from human and animal studies [PDF]
, 2015 By reducing energy density, low-energy sweeteners (LES) might be expected to reduce energy intake (EI) and body weight (BW). To assess the totality of the evidence testing the null hypothesis that LES exposure (versus sugars or unsweetened alternatives ...
de Graaf, C +10 more
core +5 more sources
Journal of Applied Veterinary Science and Technology, 2023 Background: Rhodamin B and saccharin are chemicals that are harmful to the health of the body. Consumption of rhodamine B and saccharin for a long time can cause problems for the body such as impaired organ function.
Dzakiyyah Salmaa +5 more
doaj +1 more source
Unexpected nucleophilic participation and rearrangement of DBU in reactions with saccharin derivatives [PDF]
, 2003 DBU attacks saccharin derivatives with subsequent rearrangement to give rise to 3-[3'-(1"-azepin-2"-onyl)propylamino]-1,2-benzisothiazole-1,1-dioxide 2 after work ...
Barkley, James V. +3 more
core +1 more source
A Review: Saccharin Discovery, Synthesis, and Applications
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2020 Saccharin is firstly synthesized in 1879. It is a very well-known as an inexpensive substitute for sugar as it is a non-caloric sweetener. The article shows the properties, use, metabolism and various synthesis and reactions of saccharine. Moreover,
Ammar A. Razzak Mahmood +1 more
doaj +1 more source
Inactivation of a CRF-dependent amygdalofugal pathway reverses addiction-like behaviors in alcohol-dependent rats. [PDF]
, 2019 The activation of a neuronal ensemble in the central nucleus of the amygdala (CeA) during alcohol withdrawal has been hypothesized to induce high levels of alcohol drinking in dependent rats.
Crawford, Elena +8 more
core +2 more sources
The impact of non-nutritive sweeteners on isolated and purified microbial cultures derived from probiotics [PDF]
Romanian Journal of Pharmaceutical Practice, 2022 Non-nutritive sweeteners (NNS) are a well-known substitute for table sugar with great implications in the management of various pathologies, mainly in Diabetes or Obesity. Previous studies have successfully shown that these substances are safe for human
Alin-George Zamfir +5 more
doaj +1 more source
The Neural Encoding of Cocaine-Induced Devaluation in The Ventral Pallidum [PDF]
, 2016 Cocaine experience affects motivation structures such as the nucleus accumbens (NAc) and its major output target, the ventral pallidum (VP). Previous studies demonstrated that both NAc activity and hedonic responses change reliably as a taste cue comes ...
Chan, Chung-Lung +2 more
core +2 more sources
Habitual Preference for the Nondrug Reward in a Drug Choice Setting
Frontiers in Behavioral Neuroscience, 2020 For adaptive and efficient decision making, it must be possible to select between habitual alternative courses of action. However, research in rodents suggests that, even in the context of simple decision-making, choice behavior remains goal-directed. In
Youna Vandaele +4 more
doaj +1 more source
CHIMIA, 1990 Large-scale synthesis of the new saccharin-derived N-fluorosultam 1 is described, starting from readily available saccharin 2. A newly designed fluorination apparatus, which allows the preparation of 100-g quantities of 1 at atmospheric pressure, is ...
Kurt Auer +2 more
doaj +5 more sources