Results 71 to 80 of about 20,124 (224)

Harnessing Free Radical Scavenging Potential of Caffeic Acid as a Nutraceutical—A Review

Food Safety and Health, EarlyView.
Caffeic acid has emerged as a promising bioactive molecule with multiple pharmacological properties, including antioxidant, antimicrobial, anti‐inflammatory, organ protective properties and metal‐chelating ability. This review emphasizes the dietary sources, structural characteristic, molecular mechanism underlying health promoting effects of caffeic ...
Pavitra Behra, Monika Bhadauria, Satendra Kumar Nirala   +2 more
wiley   +1 more source

Salvianolic acid B inhibits mitochondrial dysfunction by up-regulating mortalin [PDF]

Scientific Reports, 2017
AbstractSalvianolic acid B is an antioxidative ingredient derived from Radix Salviae miltiorrhizae that has been widely used to treat liver diseases. However, the therapeutic mechanism underlying Salvianolic acid B has remained largely unknown. Our studies verified that Salvianolic acid B efficiently blocked mitochondrial deformation and dysfunction ...
Yunxia Liu, Yingying Hu, Qiukai E, Ji Zuo, Ling Yang, Wen Liu   +5 more
openaire   +2 more sources

Melissa officinalis L. decoctions as functional beverages: a bioactive approach and chemical characterization [PDF]

, 2015
Lemon balm (Melissa officinalis L.) is a member of the Lamiaceae family with a long story of human consumption. It has been consumed for decades, directly in food and as a decoction or an infusion for its medicinal purposes.
Barros, Lillian, Calhelha, Ricardo C., Carocho, Márcio, Ferreira, Isabel C.F.R., Morales, Patricia, Santos-Buelga, Celestino, Soković, Marina, Ćirić, Ana   +7 more
core   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Changes in Cardiac Function During the Development of Uremic Cardiomyopathy and the Effect of Salvianolic Acid B Administration in a Rat Model

Frontiers in Veterinary Science, 2022
BackgroundUremic cardiomyopathy (UC), the main cause of death in progressive chronic kidney disease (CKD), is characterized by diastolic dysfunction. Intraventricular pressure gradients (IVPG) derived from color m-mode echocardiography (CMME) and two ...
Danfu Ma, Danfu Ma, Ahmed S. Mandour, Ahmed S. Mandour, Ahmed Elfadadny, Ahmed Elfadadny, Hanan Hendawy, Hanan Hendawy, Tomohiko Yoshida, Hussein M. El-Husseiny, Hussein M. El-Husseiny, Koji Nishifuji, Ken Takahashi, Zhenlei Zhou, Yanbing Zhao, Ryou Tanaka   +15 more
doaj   +1 more source

Adapting tissue-engineered in vitro CNS models for high-throughput study of neurodegeneration [PDF]

, 2017
Neurodegenerative conditions remain difficult to treat, with the continuing failure to see therapeutic research successfully advance to clinical trials. One of the obstacles that must be overcome is to develop enhanced models of disease.
Cameron, GW, Drake, RA, Lee-Reeves, C, Loughlin, AJ, O'Rourke, C, Phillips, JB   +5 more
core   +3 more sources

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Conversion of salvianolic acid B into salvianolic acid A in tissues of Radix Salviae Miltiorrhizae using high temperature, high pressure and high humidity [PDF]

Phytomedicine, 2014
Salvianolic acid A (Sal A), an important constituent of Radix Salviae Miltiorrhizae (RSM), is effective for the treatment of myocardial infarction (MI) and coronary heart disease due to its potential in the improvement of acute myocardial ischemia. However, its content is very low in RSM.
Hongrui, Xia, Longru, Sun, Hongxiang, Lou, M Mukhlesur, Rahman   +3 more
openaire   +2 more sources

Cloning and characterization of a putative R2R3 MYB transcriptional repressor of the rosmarinic acid biosynthetic pathway from Salvia miltiorrhiza.

PLoS ONE, 2013
Salvia miltiorrhiza Bunge is one of the most renowned traditional medicinal plants in China. Phenolic acids that are derived from the rosmarinic acid pathway, such as rosmarinic acid and salvianolic acid B, are important bioactive components in S ...
Shuncang Zhang, Pengda Ma, Dongfeng Yang, Wenjing Li, Zongsuo Liang, Yan Liu, Fenghua Liu   +6 more
doaj   +1 more source

Salvianolic acid A targeting the transgelin-actin complex to enhance vasoconstriction [PDF]

EBioMedicine, 2018
Salvia miltiorrhiza is used extensively to treat cardiovascular diseases. SAA is a major bioactive component in Salvia miltiorrhiza and mediates myocardial ischemia (MI). However, the industrial production of SAA is limited due to low yields. In addition, the direct targets of SAA are unknown.
Zhong, Weilong, Sun, Bo, Gao, Wenqing, Qin, Yuan, Zhang, Heng, Huai, Longcong, Tang, Yuanhao, Liang, Yuan, He, Lingfei, Zhang, Xiaoyun, Tao, Honglian, Chen, Shuang, Yang, Wei, Yang, Lan, Liu, Yanrong, Liu, Huijuan, Zhou, Honggang, Sun, Tao, Yang, Cheng   +18 more
openaire   +2 more sources