Results 171 to 180 of about 115,094,824 (204)

Research progress of salvianolic acid A

China Journal of Chinese Materia Medica, 2011
Salvianolic acid A is a water-soluble component from Danshen, which is frequently used in traditional Chinese medicine. High performance liquid chromatography was often used to analyze content of salvianolic acid A. The yield of salvianolic acid A increased by the technological improvement of extraction and separation.
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[Study on preparation of salvianolic acid phospholipid compound].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2014
To prepare salvianolic acid phospholipid compound. With the compound of salvianolic acids and soybean phospholipid as the index, mono-factor experiment and orthogonal design experiment were conducted to screen its technical parameters. According to the results, the optimal preparation conditions of salvianolic acid phospholipid compound were that THF ...
Xiao-Yun, Chen, Zhen-Hai, Zhang, Dan, Liu, Dan-Hong, Yu, E, Sun, Xiao-Bin, Jia   +5 more
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[Study on application of salvianolic acids reference extract in quality control of Salvia miltiorrhiza and salvianolic acids for injection].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2020
The purpose of this study was to investigate the feasibility of the salvianolic acids reference extract for quality control for Salvia miltiorrhiza and salvianolic acids for injection. An Agilent ZORBAX SB-C18( 4. 6 mm×250 mm,5 μm) column was used with mobile phase consisting of 0. 1% formic acid-water and 0.
Yao-Lei, Li, Li-Na, Liu, Ying, Wang, Hong-Yu, Jin, Hong-Shui, Yue, Shuang-Cheng, Ma   +5 more
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Rapid and simultaneous determination of salvianolic acid A and salvianolic acid B by complex chromatography and study on related mechanism of coordination

Analytica Chimica Acta, 2008
Abstract Salvianolic acid A (Sal A) and salvianolic acid B (Sal B) are water-soluble phenolic acids in Danshen extract and they have high medicinal value. A rapid and novel complex high-performance liquid chromatography (HPLC) method has been developed and validated for the simultaneous determination of Sal A and Sal B within 10 min.
Beibei Zhou, Jian Pan, Jia Wang
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Proteomic studies on protective effects of salvianolic acids, notoginsengnosides and combination of salvianolic acids and notoginsengnosides against cardiac ischemic-reperfusion injury

Journal of Ethnopharmacology, 2012
Salvia miltiorrhiza and Panax notoginseng are popularly used traditional Chinese medicine for cardiovascular disorders and they are often used in the form of combination. However, mechanisms of their cardioprotective effects were still not clear.
Qing-Xi, Yue, Fu-Bo, Xie, Xiao-Yi, Song, Wan-Ying, Wu, Bao-Hong, Jiang, Shu-Hong, Guan, Min, Yang, Xuan, Liu, De-An, Guo   +8 more
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[Research progress of salvianolic acid A].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2012
Salvianolic acid A is a water-soluble component from Danshen, which is frequently used in traditional Chinese medicine. High performance liquid chromatography was often used to analyze content of salvianolic acid A. The yield of salvianolic acid A increased by the technological improvement of extraction and separation.
Li, Zhang, Weiku, Zhang, Ying, Zhao, Xiuying, Yang, Lianhua, Fang, Shoubao, Wang, Lili, Shi, Xiaoyan, Yu, Subo, Wang, Haiguang, Yang, Jialin, Sun, Shuo, Tian, Guanhua, Du   +12 more
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Synthesis of (+)-salvianolic acid A from sodium Danshensu

Tetrahedron, 2018
Abstract (+)-Salvianolic acid A, one of the most active components in the traditional Chinese medicine Danshen, has been synthesized over 10 steps in 6.5% overall yield. Starting from inexpensive ortho-vanillin and sodium Danshensu (synthesized via asymmetric catalysis in our group), the process consists of the following: A Wittig reaction that gives
Kai Xu, Hao Liu, Delong Liu, Cheng Sheng, Jiefeng Shen, Wanbin Zhang   +5 more
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Towards the Synthesis of the Skeleton of Salvianolic Acid D

Synthesis, 2006
A successful synthesis of the acid part of salvianolic acid D is described (eight steps from isovanillin, 22% overall yield). The benzaldehyde key intermediate was obtained in six steps in 52% overall yield and was converted into the trimethylated precursor molecule using the Knoevenagel procedure.
Philippe Cotelle, Clémence Queffélec, Fabrice Bailly   +2 more
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Effects of salvianolic acids on oxidative stress and hepatic fibrosis in rats

Toxicology and Applied Pharmacology, 2010
Enhanced oxidative stress is associated with hepatic fibrosis. Salvianolic acids A (Sal A) and B (Sal B) have been reported to be strong polyphenolic antioxidants and free radical scavengers. The present study is to investigate if Sal A and B could attenuate oxidative stress and liver fibrosis in rats.
Ming-Kuei, Tsai, Yun-Lian, Lin, Yi-Tsau, Huang   +2 more
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Metabolism of Salvianolic Acid A and Antioxidant Activities of Its Methylated Metabolites

Drug Metabolism and Disposition, 2014
This study investigated the metabolism of salvianolic acid A (SAA) both in vivo and in vitro. Liquid chromatography-mass spectrometry analysis of drug-containing rat bile samples and bile samples hydrolyzed by glucuronidase revealed a series of methylated conjugates of SAA and its glucuronides, as well as the predominance of the methylation pathway of ...
Hui, Xu, Yanli, Li, Xin, Che, Hongcui, Tian, Huaying, Fan, Ke, Liu   +5 more
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