Results 11 to 20 of about 710,140 (248)

Salvianolic acid B: a promising cardioprotective agent [PDF]

Frontiers in Immunology
Salvia miltiorrhiza Bunge [Lamiaceae; Salviae miltiorrhizae radix et rhizoma] is a core herb in traditional Chinese medicine widely used for treating cardiovascular diseases (CVD).
Yingchun Shao, Li Zhai, Shan Jiang, Fusheng Sun, Xuedong Liu   +4 more
doaj   +3 more sources

Salvianolic acid B from Salvia miltiorrhiza bunge: A potential antitumor agent. [PDF]

Front Pharmacol, 2022
Salvia miltiorrhiza Bunge (Lamiaceae) is a perennial herb widely found in China since ancient times with a high economic and medicinal value. Salvianolic acid B (Sal-B) is an important natural product derived from Salvia miltiorrhiza and this review ...
Guo SS, Wang ZG.
europepmc   +5 more sources

Pharmacological Effects of Salvianolic Acid B Against Oxidative Damage [PDF]

Frontiers in Pharmacology, 2020
Salvianolic acid B (Sal B) is one of the main active ingredients of Salvia miltiorrhiza, with strong antioxidant effects. Recent findings have shown that Sal B has anti-inflammatory, anti-apoptotic, anti-fibrotic effects and can promote stem cell ...
Zhun Xiao, Wei Liu, Wei Liu, Yong-ping Mu, Yong-ping Mu, Hua Zhang, Hua Zhang, Xiao-ning Wang, Xiao-ning Wang, Chang-qing Zhao, Chang-qing Zhao, Jia-mei Chen, Jia-mei Chen, Ping Liu, Ping Liu, Ping Liu   +15 more
doaj   +4 more sources

Salvianolic Acid B Alleviates Liver Injury by Regulating Lactate-Mediated Histone Lactylation in Macrophages. [PDF]

Molecules
Salvianolic acid B (Sal B) is the primary water-soluble bioactive constituent derived from the roots of Salvia miltiorrhiza Bunge. This research was designed to reveal the potential mechanism of Sal B anti-liver injury from the perspective of macrophages.
Hu S, Yang Z, Li L, Yan Q, Hu Y, Zhou F, Tan Y, Pei G.   +7 more
europepmc   +2 more sources

Exploring the Mechanism of Salvianolic Acid B against Myocardial Ischemia-Reperfusion Injury Based on Network Pharmacology. [PDF]

Pharmaceuticals (Basel)
This study aimed to explore the mechanisms through which salvianolic acid B (Sal-B) exerts its effects during myocardial ischemia-reperfusion injury (MI/RI), aiming to demonstrate the potential pharmacological characteristics of Sal-B in the management ...
Mao Q, Shao C, Zhou H, Yu L, Bao Y, Zhao Y, Yang J, Wan H.   +7 more
europepmc   +2 more sources

A mussel-inspired, antibacterial, antioxidant, injectable composite hydrogel for the sustain delivery of salvianolic acid B for the treatment of frozen shoulder. [PDF]

Bioact Mater
Frozen shoulder (FS) manifests as progressively worsening pain and a reduction in shoulder range of motion (ROM). Salvianolic acid B (SaB) is recently expected to be used in the treatment of fibrosis diseases including FS. We firstly demonstrate that SaB
Yan Y, Li X, Chen C, Cui D, Wang Z, Li M, Long Y, Zhang J, Li C, Wang Z, Zhou C, Yao Z, Wang D, Hou J, Yang R.   +14 more
europepmc   +2 more sources

Possible applications of salvianolic acid B against different cancers [PDF]

Exploration of Targeted Anti-tumor Therapy, 2020
Cancer is the second death causing disease worldwide after cardiovascular abnormalities. The difficulty in treating tumor cells with more precise targeted interventions and recurrence of cancer after treatment may pose great difficulty in developing ...
Iram Shahzadi, Zain Ali, Sidra Bukhari, Acharan S Narula, Bushra Mirza, Reza Mohammadinejad   +5 more
doaj   +3 more sources

Injectable Hydrogels Based on Hyaluronic Acid and Gelatin Combined with Salvianolic Acid B and Vascular Endothelial Growth Factor for Treatment of Traumatic Brain Injury in Mice. [PDF]

Molecules
Traumatic brain injury (TBI) leads to structural damage in the brain, and is one of the major causes of disability and death in the world. Herein, we developed a composite injectable hydrogel (HA/Gel) composed of hyaluronic acid (HA) and gelatin (Gel ...
Zhou G, Cao Y, Yan Y, Xu H, Zhang X, Yan T, Wan H.   +6 more
europepmc   +2 more sources

Salvianolic acid B blocks hepatic stellate cell activation via FGF19/FGFR4 signaling

Annals of Hepatology, 2021
Introduction and objectives: The activation of hepatic stellate cells (HSCs) is the main cause of liver fibrosis. The beneficial effects of fibroblast growth factor (FGF) 19 on liver fibrosis were recently reported. The S.
Shuxia Tian, Min Chen, Bing Wang, Yonglong Han, Haonan Shang, Junming Chen   +5 more
doaj   +3 more sources

Neuroprotective mechanism of salvianolic acid B against cerebral ischemia-reperfusion injury in mice through downregulation of TLR4, p-p38MAPK, p-JNK, NF-κB, and IL-1β. [PDF]

Immun Inflamm Dis, 2023
Tissue injury and inflammation are two potential outcomes of cerebral ischemia–reperfusion (I/R) injury. Salvianolic acid B (Sal B), isolated from the roots of Salvia miltiorrhiza, is one of the major water‐soluble compounds with a wide range of ...
Zheng XF, Zhang XJ, Dong LP, Zhao JR, Zhang C, Chen R.   +5 more
europepmc   +2 more sources