Salvianolic acid B ameliorates neuroinflammation and neuronal injury via blocking NLRP3 inflammasome and promoting SIRT1 in experimental subarachnoid hemorrhage. [PDF]
Front Immunol, 2023 The nucleotide-binding oligomerization domain (NOD)-like receptor family pyrin domain containing 3 (NLRP3) inflammasome-mediated immuno-inflammatory response plays a critical role in exacerbating early brain injury (EBI) after subarachnoid hemorrhage ...
Xia D, Yuan J, Wu D, Dai H, Zhuang Z.
europepmc +2 more sources
Salvianolic acid B protects the myelin sheath around injured spinal cord axons
Neural Regeneration Research, 2016 Salvianolic acid B, an active pharmaceutical compound present in Salvia miltiorrhiza, exerts a neuroprotective effect in animal models of brain and spinal cord injury.
Zhe Zhu +4 more
doaj +3 more sources
Salvianolic acid B decreases interleukin-1β-induced colitis recurrence in mice
Chinese Medical Journal, 2020 . Background. Degree of mucosal recovery is an important indicator for evaluating the therapeutic effects of drugs in treatment of inflammatory bowel disease (IBD).
Pan-Pan Feng +9 more
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Salvianolic acid B suppresses hepatic fibrosis by inhibiting ceramide glucosyltransferase in hepatic stellate cells. [PDF]
Acta Pharmacol Sin, 2023 Li ZB +8 more
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Ginsenoside Rb1, salvianolic acid B and their combination modulate gut microbiota and improve glucolipid metabolism in high-fat diet induced obese mice [PDF]
PeerJ, 2021 Background To observe the effect of ginsenoside Rb1, salvianolic acid B and their combination on glucolipid metabolism and structural changes of gut microbiota. Methods Eight-week-old C57BL/6J mice were fed 45% high-fat diet to induce obesity.
Ying Bai +11 more
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Cardiovascular Effects of Salvianolic Acid B [PDF]
Evidence-Based Complementary and Alternative Medicine, 2013 Salvianolic acid B (SAB, Sal B) is the representative component of phenolic acids derived from the dried root and rhizome ofSalvia miltiorrhizaBge (Labiatae) which has been used widely and successfully in Asian countries for clinical therapy of various vascular disturbance-related diseases for hundreds of years.
Wang, Jie, Xiong, Xingjiang, Feng, Bo
openaire +3 more sources
Salvianolic acid B alleviates cartilage tissue damage in rat models with osteoarthritis [PDF]
Jichu yixue yu linchuang, 2023 Objective To explore whether salvianolic acid B affects cartilage tissue damage, hypoxia-inducible factor-1 (HIF-1) and vascular endothelial growth factor (VEGF) in osteoarthritis rats. Methods A rat model of osteoarthritis was constructed, and rats were
QIAN Ligang, SUN Bo, YU Bo, CHEN Kang, MA Zheng, CHEN Taoping, WANG Yunfei
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Salvianolic acid B ameliorates retinal deficits in an early-stage Alzheimer's disease mouse model through downregulating BACE1 and Aβ generation. [PDF]
Acta Pharmacol Sin, 2023 Wang MD +9 more
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Salvianolic acid-B improves fat graft survival by promoting proliferation and adipogenesis
Stem Cell Research & Therapy, 2021 Background Our previous study proved that Salvia miltiorrhiza could enhance fat graft survival by promoting adipogenesis. However, the effect of salvianolic acid B (Sal-B), the most abundant and bioactive water-soluble compound in Salvia miltiorrhiza, on
Jia-Ming Sun +6 more
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Salvianolic acid B alleviates neurological injury by upregulating stanniocalcin 1 expression. [PDF]
Ann Transl Med, 2022 Salvianolic acid B (Sal B) is a representative component of phenolic acids derived from the dried root and rhizome of Salvia miltiorrhiza Bge. (Labiatae), which promotes angiogenesis in myocardial infarction and diabetic cardiomyopathy. However, whether Sal B has a neuroprotective function in ischemic stroke by promoting angiogenesis is still unclear ...
Bi SJ +10 more
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