Results 111 to 120 of about 914,102 (311)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Sampled Data Systems Passivity and Discrete Port-Hamiltonian Systems [PDF]

, 2005
In this paper, we present a novel way to approach the interconnection of a continuous and a discrete time physical system. This is done in a way which preserves passivity of the coupled system independently of the sampling time T.
van der Schaft, Arjan, S. Stramigioli, Schaft, Arjan J. van der,, Schaft, Arjan J. van der; id_orcid, Secchi, Cristian,, Fantuzzi, Cesare,, Stramigioli, Stefano; id_orcid, SECCHI, Cristian, Stramigioli, Stefano,, AJ Van der Schaft, Schaft, Arjan J. van der, FANTUZZI, Cesare, Stramigioli, Stefano   +12 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Revisiting the Issues On Netflow Sample and Export Performance [PDF]

, 2008
The high volume of packets and packet rates of traffic on some router links makes it exceedingly difficult for routers to examine every packet in order to keep detailed statistics about the traffic which is traversing the router.
Landa, Raul, Andrew W. Moore, Rio, M, Bhatti, Saleem, Raul Landa, Xianhui Che, Haddadi, Hamed, Che, Xianhui, Landa, R, Bhatti, S, Saleem Bhatti, Moore, Andrew, Bhatti, SN, Haddadi, H, Che, X, Rio, Miguel, Che, XH, Hamed Haddadi, Miguel Rio, Moore, AW   +19 more
core   +1 more source

G²LM|LIC - Taming Counterfeits Markets with Consumer Information

, 2023
The project aimed to study whether an information campaign to improve Kenyan farmers’ ability to detect quality of agricultural inputs—such as seeds, fertilizer, and pesticides was able to help: increase usage of techniques to verify seed quality ...
Wancera Wambugu, Anne, Hsu, Eric
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Data preprocessing and fitting algorithm based on marine data sampled by multiple underwater gliders

, 2016
To our knowledge, this paper investigates the first application of the marine data sampled by multiple underwater gliders in the area of the South China Sea. We summarize six main characteristics of the sampled marine data.
Jia, Mingfei, Liu SJ(刘世杰), Li, Lu, Yu JC(俞建成), Xu, Zhenzhen, Yu, Shuo   +5 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source