Results 121 to 130 of about 914,102 (311)

The sample data for stMLnet

open access: yes, 2020
The input of stMLnet includes demo dataset and prior database. please refer to the following paper for more details: Cheng J, Yan L, Nie Q, Sun X*. Modeling and inference of spatial intercellular communications and multilayer signaling regulations using stMLnet. bioRxiv. 2022.   Files and datails: ex_databases: demo database `ex_databases`
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Sampled-data stabilization for Takagi-Sugeno fuzzy systems using membership function deviations

open access: yes, 2012
This paper is concerned with sampled-data stabilization for Takagi-Sugeno (T-S) fuzzy systems by using the property of membership function deviations.
Qing-Long Han (9801650)   +2 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Towards Informative Statistical Flow Inversion

open access: yes, 2012
This is the accepted version of 'Towards Informative Statistical Flow Inversion', archived originally at arXiv:0705.1939v1 [cs.NI] 14 May 2007.A problem which has recently attracted research attention is that of estimating the distribution of flow sizes ...
Landa, R, Clegg, RG, Haddadi, H, Rio, M
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Discard sampling of the Dutch pelagic freezer fishery in 2003-2007

open access: yes, 2008
This report contains the results of the discard sampling programme on the Dutch pelagic trawl fisheries in the North East Atlantic in the period 2003-2007, which was instigated as part of the EC regulation 1543/2000 and 1639/2001 on data collection in ...
Helmond, A.T.M., van   +3 more
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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