Results 181 to 190 of about 5,249 (228)

Isolation from Argemone Oil of Dihydrosanguinarine and Sanguinarine : Toxicity of Sanguinarine

Nature, 1948
ARGEMONE oil has received considerable attention during recent years on account of its alleged etiological role in epidemic dropsy1-4. I pointed out5 certain anomalies of the mustard oil - argemone oil theory of epidemic dropsy and stressed the fact that a definite solution of the problem could only be arrived at by isolating the active principle from ...
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Sanguinarine: an evaluation of in vivo cytogenetic activity

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2004
Sanguinarine (SG), a benzophenanthridine alkaloid, has been shown to possess anti-microbial, anti-inflammatory and antioxidant properties. In the UK and USA its salts has been in use in mouthwashes and toothpastes to inhibit dental plaque and improve gingival health.
Aparajita, Das, Anita, Mukherjee, J, Chakrabarti   +2 more
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Suppression of angiogenesis by the plant alkaloid, sanguinarine

Biochemical and Biophysical Research Communications, 2004
Sanguinarine is a benzophenanthridine alkaloid derived from the root of Sanguinaria canadensis. Its principal pharmacologic use is in dental products where it has antibacterial, antifungal, and anti-inflammatory activities that reduce gingival inflammation and supragingival plaque formation.
Eun, JP, Koh, GY Koh, Gou Young
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Sanguinarine and Its Role in Chronic Diseases

2016
The use of natural products derived from plants as medicines precedes even the recorded human history. In the past few years there were renewed interests in developing natural compounds and understanding their target specificity for drug development for many devastating human diseases.
Pritha, Basu, Gopinatha Suresh, Kumar
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Photochemical conversion of sanguinarine to oxysanguinarine

Journal of Photochemistry and Photobiology A: Chemistry, 1997
Abstract The photochemical properties of the alkanolamine form of sanguinarine, a benzophenanthridine plant alkaloid, were studied using absorption, fluorescence and high pressure liquid chromatography techniques. An excitation time dependent decrease in the fluorescence intensity of its emission maximum, along with changes in the emission and ...
G.Suresh Kumar, A. Das, M. Maiti
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Comparative antiplaque activity of sanguinarine and chlorhexidine in man

Journal of Clinical Periodontology, 1990
Abstract This clinical investigation examined the effect of a sanguinarine extract on bacterial plaque growth in man. Three different mouthrinses were examined: (i) Veadent® containing 0.03% sanguinarine and 0.2% zinc chloride (test rinse); (ii) a vehicle solution containing all the excipients of Veadent® except the 0.03% sanguinarine (control rinse); (
M, Quirynen, M, Marechal, D, van Steenberghe   +2 more
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Synthesis of sanguinarine, chelerythrine, and oxysanguinarine

Collection of Czechoslovak Chemical Communications, 1984
Benzo[c]phenanthridines Va and Vb have been prepared by photocyclization of amines IVa and IVb and transformed into the alkaloids sanguinarine (VIa) and chelerythrine (VIb). Oxysanguinarine (XIV) has been prepared from diazoketone XVIII.
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Effect of sanguinarine on ventricular refractoriness.

Research communications in chemical pathology and pharmacology, 1980
The purpose of this study was to determine the effect of the Na+K+ATPase inhibitor sanguinarine on the refractory period of the porcine ventricle. Measurements of ventricular refractoriness and strength-interval curves were obtained before and after 0.5 to 4.0 mg/kg sanguinarine.
J A, Whittle, J K, Bissett, K D, Straub, J E, Doherty, J R, McConnell   +4 more
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Antimicrobial action of sanguinarine.

The Journal of clinical dentistry, 1990
Sanguinarine is a benzophenanthridine alkaloid derived from rhizomes of Sanguinaria canadensis L. (bloodroot). It is a cationic molecule which converts from an iminium ion form at pH less than 6 to an alkanolamine form at pH greater than 7. Sanguinaria extract is composed of sanguinarine and five other closely related alkaloids.
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The synthesis of sanguinarine

Tetrahedron Letters, 1968
S F, Dyke, B J, Moon, M, Sainsbury
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