Results 11 to 20 of about 6,019,041 (305)

GelMA-based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma. [PDF]

FEBS Open Bio
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Germain N, Buret E, Nguyen LHT, Cocheteux M, Touya N, Dhayer M, Dubois R, Lafont F, Janel S, Maboudou P, Lancel S, Marchetti P.   +11 more
europepmc   +2 more sources

Multimodal Imaging of Hypoxia, Metabolism and pH in Feline Sarcoma Using Hyperpolarized ¹³C MRI and PET. [PDF]

Adv Sci (Weinh)
This work presents a clinically deployable simultaneous PET/MRI workflow which integrates hyperpolarized 13C imaging of metabolism and extracellular pH with [18F]FMISO PET to characterize hypoxia, acidosis, and metabolic reprogramming in feline sarcoma.
Grashei M, Groll T, Kahl S, Baer S, Bliemsrieder E, van Heijster FHA, Wendlinger A, Wodtke P, Cabello J, Notohamiprodjo S, Lohrmann C, Schwaiger M, Weber WA, Steiger K, Meyer-Lindenberg A, Hirschberger J, Baumgartner C, Schilling F.   +17 more
europepmc   +2 more sources

The Prognostic Value of Serum Biomarkers in Localized Bone Sarcoma

Translational Oncology, 2016
OBJECTIVE: Certain biomarkers such as the C-reactive protein, serum albumin, and the neutrophils to lymphocyte ratio are of prognostic significance regarding survival in different types of cancers. Data from sarcoma patients are sparse and mainly derived
Ninna Aggerholm-Pedersen, Katja Maretty-Kongstad, Johnny Keller, Steen Baerentzen, Akmal Safwat   +4 more
doaj   +1 more source

Implantação intracerebral experimental de sarcomas Experimental intracerebral implantation of sarcomas [PDF]

Memorias do Instituto Oswaldo Cruz, 1972
Estudo histopatológico da implantação intracerebral de sarcomas, realizado em ratos (fibrosarcoma) e em camundongos (sarcoma 180). A implantação intracerebral de fibrosarcoma desenvolveu, em cerca de 45 dias, neoplasia relativamente bem delimitada, com pequena infiltração do parênquima nervoso adjacente, nunca se propagando a maiores distãncias devido ...
openaire   +4 more sources

Research on imbalance machine learning methods for MR $$T_1$$ T 1 WI soft tissue sarcoma data

BMC Medical Imaging, 2022
Background Soft tissue sarcoma is a rare and highly heterogeneous tumor in clinical practice. Pathological grading of the soft tissue sarcoma is a key factor in patient prognosis and treatment planning while the clinical data of soft tissue sarcoma are ...
Xuanxuan Liu, Li Guo, Hexiang Wang, Jia Guo, Shifeng Yang, Lisha Duan   +5 more
doaj   +1 more source

PI3K inhibition enhances doxorubicin-induced apoptosis in sarcoma cells [PDF]

, 2012
We searched for a drug capable of sensitization of sarcoma cells to doxorubicin (DOX). We report that the dual PI3K/mTOR inhibitor PI103 enhances the efficacy of DOX in several sarcoma cell lines and interacts with DOX in the induction of apoptosis ...
Dittmann, Kai, Ridzewski, Rosalie, Diana Marklein (105976), Albert Rosenberger (28881), Diana Marklein, Kai Dittmann (105997), Simone Fulda, Rosalie Ridzewski, Jürgen Wienands, Ulrike Graab, Wienands, Juergen, Simone Fulda (106002), Graab, Ulrike, Frauke Nitzki, Nitzki, Frauke, Rosenberger, Albert, Tiandong Yan, Kai Dittmann, Yan, Tiandong, Yan, T., Heidi Hahn (106003), Naumann, Ivonne, Heidi Hahn, Fulda, Simone, Ivonne Naumann, Wienands, Jürgen, Ivonne Naumann (105981), Leszek Wojnowski (106001), Wojnowski, Leszek, Marklein, Diana, Ulrike Graab (105978), Tiandong Yan (105985), Jürgen Wienands (105999), Hahn, Heidi, Albert Rosenberger, Frauke Nitzki (105993), Leszek Wojnowski, Rosalie Ridzewski (105989)   +37 more
core   +1 more source

Evolution of sarcoma 180 (ascitic tumor) in mice infected with Schistosoma mansoni

Revista da Sociedade Brasileira de Medicina Tropical, 1986
Mice infected with 60 cercariae of Schistosoma mansoni were more resistant to the sarcoma 180 ascites tumor. Tumor inoculation was performed 50 days after schistosoma infection and the animals were observed and weighed at 48 hours intervals for ...
Fausto Edmundo Lima Pereira, Pedro Raso, Paulo Marcos Zech Coelho   +2 more
doaj   +3 more sources

PARP1 expression drives the synergistic antitumor activity of trabectedin and PARP1 inhibitors in sarcoma preclinical models

Molecular Cancer, 2017
Background Enhancing the antitumor activity of the DNA-damaging drugs is an attractive strategy to improve current treatment options. Trabectedin is an isoquinoline alkylating agent with a peculiar mechanism of action.
Ymera Pignochino, Federica Capozzi, Lorenzo D’Ambrosio, Carmine Dell’Aglio, Marco Basiricò, Marta Canta, Annalisa Lorenzato, Francesca Vignolo Lutati, Sandra Aliberti, Erica Palesandro, Paola Boccone, Danilo Galizia, Sara Miano, Giulia Chiabotto, Lucia Napione, Loretta Gammaitoni, Dario Sangiolo, Maria Serena Benassi, Barbara Pasini, Giovanna Chiorino, Massimo Aglietta, Giovanni Grignani   +21 more
doaj   +1 more source

Seroprevalence of Kaposi sarcoma-associated herpesvirus and other serologic markers in the Brazilian Amazon. [PDF]

, 2009
To determine the presence of Kaposi sarcoma-associated herpesvirus (KSHV) and other serologic markers, we tested serum specimens of 339 Amerindians, 181 rural non-Amerindians, and 1,133 urban blood donors (13 Amerindians) in the Brazilian Amazon.
Mascheretti, Melissa, Laura M. Sumita, Nascimento, Maria C, SUMITA, Laura M., Weiss, Helen A, NASCIMENTO, Maria C., Maria C. Nascimento, Sabino, Ester, Souza, Vanda U, VELA, Rodrigo A. R., Quiroga, Mariana, Melissa Mascheretti, SOUZA, Vanda U., PANNUTI, Claudio S., Mariana Quiroga, Vela, Rodrigo AR, Helen A. Weiss, Nuno R. Faria, Vanda U. Souza, Pannuti, Claudio S, Mayaud, Philippe, Rodrigo A.R. Vela, Sumita, Laura M, Oliveira, Juliane, Juliane Oliveira, Philippe Mayaud, Claudio S. Pannuti, WEISS, Helen A.   +27 more
core   +1 more source

Experimental Sarcoma of the Fowl [PDF]

The American Journal of the Medical Sciences, 1911
n ...
openaire   +2 more sources