Results 21 to 30 of about 6,019,041 (305)

Killing of Kaposi's sarcoma-associated herpesvirus-infected fibroblasts during latent infection by activated natural killer cells. [PDF]

, 2011
Kaposi's sarcoma-associated herpesvirus (KSHV) establishes life-long infection by evading clearance by the host immune system. In de novo infection and lytic replication, KSHV escapes cytotoxic T cells and NK cells through downregulation of MHC class-I ...
Nick C. Matthews, Gotch, FM, Frances M. Gotch, Robey, Rebecca C, Bower, Mark, Rebecca C. Robey, Mark Bower, Matthews, Nick C, Goodier, Martin R, Bower, M, Goodier, MR, Robey, RC, Gotch, Frances M, Martin R. Goodier, Matthews, NC   +14 more
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Kaposin-B enhances the PROX1 mRNA stability during lymphatic reprogramming of vascular endothelial cells by Kaposi's sarcoma herpes virus. [PDF]

, 2010
Kaposi's sarcoma (KS) is the most common cancer among HIV-positive patients. Histogenetic origin of KS has long been elusive due to a mixed expression of both blood and lymphatic endothelial markers in KS tumor cells.
Kafka, Darren, Koh, Chester J., Aguilar Berenice, Yoo, Jaehyuk, Hong Young-Kwon, Hong, Young-Kwon, Lee, Sunju, Choi, Inho, Yoo Jaehyuk, Haas, Jürgen G., Kang Jinjoo, Lee Ha Neul, Swapnika Ramu, Kang, Jinjoo, Young-Kwon Hong, Juneyong Lee, Ramu, Swapnika, Darren Kafka, Lee, Juneyong, Kafka Darren, Lee Sunju, Choi Inho, Juergen Haas, Haas, Juergen, Lee Juneyong, Sunju Lee, Inho Choi, Ha Neul Lee, Haas Juergen, Aguilar, Berenice, Chester J. Koh, Jinjoo Kang, Chester J Koh, Jaehyuk Yoo, Koh Chester J., Berenice Aguilar, Ramu Swapnika, Lee, Ha Neul   +37 more
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3D tumor explant as a novel platform to investigate therapeutic pathways and predictive biomarkers in cancer patients

Frontiers in Immunology, 2022
Immunotherapy with immune checkpoint inhibitors can induce durable clinical responses in different human malignancies but the number of responding patients remains globally modest.
Monica Rodolfo, Veronica Huber, Mara Cossa, Gianfrancesco Gallino, Biagio E. Leone, Viviana Vallacchi, Licia Rivoltini, Elisabetta Vergani   +7 more
doaj   +1 more source

Effect of Blood Transfusion in an Experimental Sarcoma Model [PDF]

Archives of Otolaryngology–Head & Neck Surgery, 2002
To study the effect of allogeneic, syngeneic, and autologous blood transfusion on the growth rate of the KHT tumor in a C3H murine model.Prospective, randomized, and controlled animal study.Sixty-one C3H female mice.The C3H female mice were implanted with 2 x 10(5) cells of KHT, a murine sarcoma. Ten days later, 0.3 mL of blood was removed from a retro-
Ho-Sheng, Lin, Ravi N, Samy, Joanne, Lum, Mary Jo, Dorie, David J, Terris   +4 more
openaire   +2 more sources

EXPERIMENTAL PRODUCTION AND TRANSMISSION OF TAR SARCOMAS IN CHICKENS [PDF]

Journal of Experimental Medicine, 1925
Two spindle cell sarcomas have developed as the result, of injection of coal tar into induced embryomas in chickens. One of these, transplanted to other chickens for eleven generations, is highly invasive in character, and metastasizes freely. Attempts to transmit this neoplasm by a filtrate or desiccate of the tumor have failed of success.
J B, Murphy, K, Landsteiner
openaire   +2 more sources

NEDDylation is essential for Kaposi's sarcoma-associated herpesvirus latency and lytic reactivation and represents a novel anti-KSHV target. [PDF]

, 2015
Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi's sarcoma (KS) and primary effusion lymphoma (PEL), which are aggressive malignancies associated with immunocompromised patients.
Wood, Jennifer J, Baquero, B, Jennifer J Wood, Adrian Whitehouse, Belinda Baquero-Pérez (706834), Hughes, DJ, David J Hughes, Whitehouse, A, Jackson, BR, Whitehouse, Adrian, Hughes, David John, Jackson, Brian R, Belinda Baquero-Pérez, Adrian Whitehouse (179093), Brian R Jackson, Brian R. Jackson (233567), Wood, JJ, Jennifer J. Wood (706833), David J. Hughes (167294), Baquero-Pérez, Belinda   +19 more
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A Trp53fl/flPtenfl/fl mouse model of undifferentiated pleomorphic sarcoma mediated by adeno-Cre injection and in vivo bioluminescence imaging. [PDF]

PLoS ONE, 2017
Genetic mouse models of soft tissue sarcoma provide critical insights into disease pathophysiology, which are oftentimes unable to be extracted from human tumor samples or xenograft models.
Marisa R Buchakjian, Nicole M Merritt, Devon L Moose, Adam J Dupuy, Munir R Tanas, Michael D Henry   +5 more
doaj   +1 more source

Kaposi's sarcoma herpesvirus microRNAs target caspase 3 and regulate apoptosis [PDF]

, 2011
Kaposi's sarcoma herpesvirus (KSHV) encodes a cluster of twelve micro (mi)RNAs, which are abundantly expressed during both latent and lytic infection.
Contrant, M, Johanna Viiliäinen, Vladimir Benes, Päivi M. Ojala, Voinnet Olivier, Gros, Frédéric, Voinnet, Olivier, Viiliainen, J, Mihaela Zavolan, Benes, Vladimir, Haas Juergen G., Suffert, G, Georg Malterer, Guillaume Suffert, Malterer, G, Frédéric Gros, Gros Frédéric, Ojala, Päivi M, Viiliäinen, Johanna, Suffert, Guillaume, Olivier Voinnet, Hausser Jean, Fender, A, Malterer Georg, Benes, V, Zavolan Mihaela, Ojala Päivi M., Haas, JG, Päivi M Ojala, Hausser, J, Viiliäinen Johanna, Zavolan, Mihaela, Hausser, Jean, Voinnet, O, Suffert Guillaume, Maud Contrant, Pfeffer Sébastien, Haas, Jürgen G., Zavolan, M, Jean Hausser, Tomi Ivacevic, Contrant Maud, Malterer, Georg, Benes Vladimir, Sébastien Pfeffer, Fender Aurélie, Haas, Juergen G, Ivacevic, T, Ojala, PM, Juergen G Haas, Ivacevic, Tomi, Aurélie Fender, Fender, Aurélie, Ojala, Päivi M., Pfeffer, Sébastien, Gros, F, Pfeffer, S, Contrant, Maud, Juergen G. Haas, Ivacevic Tomi, Haas, Juergen G.   +60 more
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Effect of Educational Guidelines on Mothers' Knowledge, Reported Practices, and Anxiety regarding their Children having Ewing Sarcoma [PDF]

Egyptian Journal of Health Care
Background: Ewing tumors, also called Ewing sarcomas, are a class of malignancies that originate in the surrounding soft tissues or bones and have a few characteristics as common.
Heba Boshra Shehata, Amal Abo El-Azm Abd El - Rahman Younis, Ohoud Youssef EL-Sheikh, Mai Nour Eldien Mohamed Mohamed Awad, Lamiaa Moustafa Elbosaty, Mariana Erian Shehata   +5 more
doaj   +1 more source

The KrasG12D;Trp53fl/fl murine model of undifferentiated pleomorphic sarcoma is macrophage dense, lymphocyte poor, and resistant to immune checkpoint blockade.

PLoS ONE, 2021
Sarcomas are rare, difficult to treat, mesenchymal lineage tumours that affect children and adults. Immunologically-based therapies have improved outcomes for numerous adult cancers, however, these therapeutic strategies have been minimally effective in ...
Karys M Hildebrand, Arvind K Singla, Reid McNeil, Kayla L Marritt, Kurt N Hildebrand, Franz Zemp, Jahanara Rajwani, Doha Itani, Pinaki Bose, Douglas J Mahoney, Frank R Jirik, Michael J Monument   +11 more
doaj   +1 more source