Results 71 to 80 of about 42,993 (322)
eLife, 2018 Muscles organise pseudo-crystalline arrays of actin, myosin and titin filaments to build force-producing sarcomeres. To study sarcomerogenesis, we have generated a transcriptomics resource of developing Drosophila flight muscles and identified 40 ...
Maria L. Spletter +10 more
semanticscholar +1 more source
Sarcomeric TPM3α in developing chicken [PDF]
Cytoskeleton, 2017 AbstractCloning and sequencing of various tropomyosin isoforms expressed in chickens have been described since the early 1980s. However, to the best of our knowledge, this is the first report on the molecular characterization and the expression of the sarcomeric isoform of the TPM3 gene in cardiac and skeletal muscles from developing as well as adult ...
Syamalima, Dube +8 more
openaire +2 more sources
Advanced Science, EarlyView.This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen +31 more
wiley +1 more source
Frontiers in PhysiologyThe transverse–axial tubular system (TATS) is the extension of sarcolemma growing to the cell interior, providing sufficient calcium signaling to induce calcium release from sarcoplasmic reticulum cisternae and stimulate the contraction of neighboring ...
Zuzana Sevcikova Tomaskova +1 more
doaj +1 more source
Altered Sarcomeric Structure and Function in Woody Breast Myopathy of Avian Pectoralis Major Muscle
Frontiers in Physiology, 2020 The “Woody” or “Wooden” breast disease is a severe myopathy of pectoralis major muscle recently identified within rapidly growing broiler lines all around the world with a prevalence rate around 20%, or even higher.
Jiao Liu +4 more
doaj +1 more source
Meat and Muscle Biology, 2021 Woody breast syndrome is characterized by degenerative changes at the muscle fiber level and accumulation of connective tissue between the fibers.
Crisitina Costandache +2 more
doaj +2 more sources
Advanced Science, EarlyView.Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao +4 more
wiley +1 more source
The Drosophila formin Fhos is a primary mediator of sarcomeric thin-filament array assembly
eLife, 2016 Actin-based thin filament arrays constitute a fundamental core component of muscle sarcomeres. We have used formation of the Drosophila indirect flight musculature for studying the assembly and maturation of thin-filament arrays in a skeletal muscle ...
Arkadi Shwartz +3 more
doaj +1 more source
Geometrically Encoded Positioning of Introns, Intergenic Segments, and Exons in the Human Genome
Advanced Science, EarlyView.This study introduces a new hypothesis: exons, introns, and intergenic segments are non‐random projections of the functional layers of 3D structure of chromatin packing domains. Evidence is presented that this “geometric code” may encode volumetric structure, reconciling epigenetic patterns, correlates with oncogenic mutations, acting as a potential ...
Luay M. Almassalha +11 more
wiley +1 more source
eLife, 2023 Measuring the positions and dynamics of proteins in intact tissues or whole animals is key to understanding protein function. However, to date, this is challenging, as the accessibility of large antibodies to dense tissues is often limited, and ...
Vincent Loreau +10 more
doaj +1 more source