Results 31 to 40 of about 11,481 (144)
Skeletal Muscle in Cerebral Palsy: From Belly to Myofibril
Frontiers in Neurology, 2021 This review will provide a comprehensive, up-to-date review of the current knowledge regarding the pathophysiology of muscle contractures in cerebral palsy.
Jason J. Howard, Walter Herzog
doaj +1 more source
Aggregate, Volume 4, Issue 1, February 2023., 2023 Organ‐on‐chip platforms have the potential to revolutionize personalized therapies by a more realistic recapitulation of human organs in vitro, enabling the study of therapeutical outcomes and conceivable adverse side‐effects of administered medicine.
Sajjad Rahmani Dabbagh +5 more
wiley +1 more source
3D bioprinting and its innovative approach for biomedical applications
MedComm, Volume 4, Issue 1, February 2023., 2023 Design and discovery pipeline of 3D bioprinting technology for biomedical applications. Abstract 3D bioprinting or additive manufacturing is an emerging innovative technology revolutionizing the field of biomedical applications by combining engineering, manufacturing, art, education, and medicine.
Swikriti Tripathi +3 more
wiley +1 more source
The importance of serial sarcomere addition for muscle function and the impact of aging
, 2023 During natural aging, skeletal muscle experiences impairments in mechanical performance due, in part, to changes in muscle architecture and size, notably with a loss of muscle cross-sectional area (CSA).
Franchi M. V. +3 more
core +1 more source
PLoS Genetics, 2022 Myofibrils of the skeletal muscle are comprised of sarcomeres that generate force by contraction when myosin-rich thick filaments slide past actin-based thin filaments.
Joachim Berger +2 more
doaj +1 more source
Serum response factor orchestrates nascent sarcomerogenesis and silences the biomineralization gene program in the heart [PDF]
Proceedings of the National Academy of Sciences, 2008 Our conditional serum response factor (SRF) knockout, Srf Cko , in the heart-forming region blocked the appearance of rhythmic beating myocytes, one of the earliest cardiac defects caused by the ablation of a cardiac-enriched ...
Zhiyv, Niu +7 more
openaire +2 more sources
The RNA-binding protein Rbm38 is dispensable during pressure overload-induced cardiac remodeling in mice. [PDF]
PLoS ONE, 2017 The importance of tightly controlled alternative pre-mRNA splicing in the heart is emerging. The RNA binding protein Rbm24 has recently been identified as a pivotal cardiac splice factor, which governs sarcomerogenesis in the heart by controlling the ...
Maarten M G van den Hoogenhof +7 more
doaj +1 more source
Acute effects of gastrocnemius muscle stretching after contusion in rats
Fisioterapia e Pesquisa, 2014 The aim of this study was to evaluate the acute effects of stretching after gastrocnemius contusion in rats. Thirty-three male Wistar rats were selected (8 weeks, 219±35 g) and divided into 4 groups: Control (CG, n=3) - intact; Lesion (LG, n=10 ...
Ana Carolina Brandt de Macedo +4 more
doaj +2 more sources
Force Generation via β-Cardiac Myosin, Titin, and α-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions. [PDF]
, 2018 Truncating mutations in the sarcomere protein titin cause dilated cardiomyopathy due to sarcomere insufficiency. However, it remains mechanistically unclear how these mutations decrease sarcomere content in cardiomyocytes.
Seidman, Christine E +21 more
core +1 more source
We will aim to review the data on sarcomerogenesis and RT at different muscle lengths alongside muscle hypertrophy ...
Menno Henselmans +7 more
core +3 more sources