Results 51 to 60 of about 21,252 (294)

TISSUE CHOLINESTERASE LEVELS IN SARIN POISONING

, 1960
The cholinesterase activity of brains and muscles from animals which have been treated with the enzyme inhibitor sarin can be estimated by a method which removes unreacted sarin present in the tissues.
J. Shuster, J. F. Scaife
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Closer Look at Adsorption of Sarin and Simulants on Metal-Organic Frameworks

, 2023
The development of effective protection against exposure to chemical warfare agents (CWAs), such as sarin, relies on studies of its adsorption on the capturing materials and seeking candidates capable of adsorbing large amounts of sarin gas.
Reed, Allen, Gor, Gennady Y., Basharova, Elizaveta A., Emelianova, Alina, Kolesnikov, Andrei L.   +4 more
core   +2 more sources

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Rapid destruction of sarin surrogates by gas phase reactions with focus on diisopropyl methylphosphonate (DIMP)

Defence Technology, 2021
Rapid destruction of stockpiles of sarin and other chemical weapon agents (CWA) requires understanding and quantitative description of the relevant chemical reactions.
Elif Irem Senyurt, Mirko Schoenitz, Edward L. Dreizin   +2 more
doaj   +1 more source

Discovery of Novel Non-Oxime Reactivators Showing In Vivo Antidotal Efficiency for Sarin Poisoned Mice

Molecules, 2022
A family of novel efficient non-oxime compounds exhibited promising reactivation efficacy for VX and sarin inhibited human acetylcholinesterase was discovered. It was found that aromatic groups coupled to Mannich phenols and the introduction of imidazole
Zhao Wei, Xinlei Zhang, Huifang Nie, Lin Yao, Yanqin Liu, Zhibing Zheng, Qin Ouyang   +6 more
doaj   +1 more source

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto, Umberto Pensato, Ilaria Casetta, Giorgio U. Marcello, Angelo Barra, Anna Poggesi, Edoardo Carlesi, Sara Mancini, Andrea Ginestroni, Vittorio Miele, Alessandro Padovani, Andrea Morotti, Enrico Fainardi   +12 more
wiley   +1 more source

Sarin

, 2016
Noções básicas de QuímicaApresenta, de forma tridimensional, a fórmula estrutural da molécula Sarin (gás)Componente Curricular::Ensino Médio::QuímicaComponente Curricular::Educação Superior::Ciências Exatas e da Terra::QuímicaComponente Curricular ...
Paiva, João
core   +1 more source

Transcriptional responses of the nerve agent-sensitive brain regions amygdala, hippocampus, piriform cortex, septum, and thalamus following exposure to the organophosphonate anticholinesterase sarin

Journal of Neuroinflammation, 2011
Background Although the acute toxicity of organophosphorus nerve agents is known to result from acetylcholinesterase inhibition, the molecular mechanisms involved in the development of neuropathology following nerve agent-induced seizure are not well ...
Meyerhoff James L, Robison Christopher L, Lumley Lucille A, Spradling Kimberly D, Dillman James F   +4 more
doaj   +1 more source