Results 71 to 80 of about 64,872 (306)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Theoretical study of the molecular aspect of the suspected novichok agent A234 of the Skripal poisoning [PDF]

open access: yesRoyal Society Open Science, 2019
Novichoks are the suspected nerve agents in the March 2018 Skripal poisoning. In this context, the novichok agent A234 (chemical structure proposed by Mirzayanov) was studied using computational methods to shed light on its molecular, electronic ...
Hanusha Bhakhoa   +2 more
doaj   +1 more source

Syria and the Responsibility to Protect [PDF]

open access: yes, 2020
The civilian protection agenda has tried to fill critical gaps in the existing normative architecture through the Responsibility to Protect (R2P) and protection of civilians (POC) as sibling norms.1 Despite these two valuable additions to the repertoire ...
Thakur, Ramesh
core  

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano   +11 more
wiley   +1 more source

THE MEANING OF NASEEM’S LOVE REFLECTED IN VIC SARIN’S PARTITION MOVIE (2007): A HUMANISTIC PSYCHOLOGICAL APPROACH [PDF]

open access: yes, 2011
This study is proposed to reveal how the meaning of Naseem’s love reflected in Partition directed by Vic Sarin which is published in 2007. The object of the study is the Partition movie directed by Vic Sarin.
ARIYANTO, NIKA
core  

Using rank data to estimate health state utility models [PDF]

open access: yes, 2006
In this paper we report the estimation of conditional logistic regression models for the Health Utilities Index Mark 2 and the SF-6D, using ordinal preference data.
Aki Tsuchiya   +24 more
core   +1 more source

Reperfusion‐Dependent Outcomes After Endovascular Thrombectomy Stratified by NIHSS‐ASPECTS Clinical‐Core Mismatch

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht   +53 more
wiley   +1 more source

Nerve agents: A clear and present danger to mankind [PDF]

open access: yesScripta Medica, 2019
This editorial is written on the occasion of the 25th anniversary of the infamous sarin and VX terrorist attacks in Japan, in order to increase the awareness of the potential terrorist use of nerve agents and to urge the preparedness to cope with its ...
Stojiljković Miloš P.
doaj  

Two Varieties of Moral Exemplarism [PDF]

open access: yes, 2018
References to moral exemplars run deep into the history of philosophy, as we find them featured in rather disparate context and approaches which span from virtue ethics to moral perfectionism, from existentialism to moral particularism. In the varied and
Marchetti, Sarin
core  

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

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