Results 61 to 70 of about 21,252 (294)

OXIMES AND ATROPINE IN SARIN POISONING [PDF]

British Journal of Pharmacology and Chemotherapy, 1957
Three oximes, monoisonitrosoacetone (MINA), pyridine‐2‐aldoxime methiodide (PAM) and diacetylmonoxime (DAM), have been examined in combination with atropine as antidotes in sarin poisoning. When treatment was administered 15 min. before sarin, atropine enhanced the protective effect of MINA and DAM 2 to 3 times and of PAM 9 to 10 times in mice and rats.
openaire   +2 more sources

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Dynamic response and discrimination of gaseous sarin using a boron‐difluoride complex film‐based fluorescence sensor

Aggregate
This study presents a novel boron‐difluoride complex‐based fluorescent nanofilm sensor capable of detecting sarin vapors in the environment by reporting an output fluorescence signal.
Zhijie Zhou, Lei Zhang, Lingya Peng, Yingjie Li, Xiaolin Zhu, Yidi Wu, Zebiao Qiu, Gang He, Molin Qin, Haonan Peng, Yu Fang   +10 more
doaj   +1 more source

Chemical Warfare Agent: Toxicity and Health Effects of Sarin Gas (GB)

Baghdad Journal of Biochemistry and Applied Biological Sciences
Chemical warfare agents (CWAs) are toxic substances used to cause harm, injury, or incapacitation to an adversary in the context of warfare and related military activities.
Zeravan A. S. Ali Ali, Azzam A. Mosa Mosa, Mohammed A. Hami Hami, Rana T Altaee   +3 more
doaj   +1 more source

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

Do environmental quality standards for selected nerve agents ensure safety of the ecosystems? / Czy istniejące standardy jakości środowiska dla wybranych fosforoorganicznych bojowych środków trujących zapewniają również ochronę ekosystemów?

Environmental Protection and Natural Resources, 2013
Zagrożenie i ryzyko powodowane fosforoorganicznymi bojowymi środkami trującymi w stosunku do ludzi i organizmów wyższych jest stosunkowo dobrze rozpoznane i zbadane, jednakże dane naukowe dotyczące środowiskowego oddziaływania tego typu substancji są ...
Kalinowski Radosław, Chrzanowska Edyta, Brytan Marek   +2 more
doaj   +1 more source

Theoretical study of the molecular aspect of the suspected novichok agent A234 of the Skripal poisoning [PDF]

Royal Society Open Science, 2019
Novichoks are the suspected nerve agents in the March 2018 Skripal poisoning. In this context, the novichok agent A234 (chemical structure proposed by Mirzayanov) was studied using computational methods to shed light on its molecular, electronic ...
Hanusha Bhakhoa, Lydia Rhyman, Ponnadurai Ramasami   +2 more
doaj   +1 more source

Neurodegeneration and Neuroinflammation in a Mouse Model of Sarin Exposure [PDF]

, 2007
Sarin is an organophosphorus (OP) ester chemical warfare agent (CWA) that has been used in past terrorist attacks. It remains a threat today because of its ease of manufacture and dispersal.
Davidson, Molly Elizabeth
core   +1 more source

A Simplified Laminar Flow Model for the Pultrusion of Glass Fiber/Polyethylene Terephthalate Commingled Yarns

Advanced Engineering Materials, EarlyView.
A simplified thermoplastic pultrusion model is developed to predict thermal fields in glass fiber/polyethylene terephthalate (GF/PET) composites with reduced computational cost. By combining effective material homogenization, validation against literature data, and Gaussian‐process‐based optimization, the study reveals how heating limits, pulling speed,
Elder Soares, Nadège Bouchonneau, Christian Jochum, Donald Radford   +3 more
wiley   +1 more source

Influence of TiC and TiN Ceramic Reinforcements on the Microstructure, Thermal Expansion Behavior, and Tensile Properties of Invar 36 Manufactured by Laser Powder Bed Fusion

Advanced Engineering Materials, EarlyView.
This study examines Invar composites reinforced with titanium carbide (TiC) and titanium nitride (TiN) using laser powder bed fusion (LPBF). It presents the influence of reinforcements on microstructure, tensile properties, and thermal expansion. Results show that TiC effectively strengthens Invar while maintaining low thermal expansion, whereas TiN ...
Ayodeji Nathaniel Oyedeji, Natasha Sacks, Johannes Pötschke, Björn Matthey   +3 more
wiley   +1 more source