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The Many Roles of Macrophages in Skeletal Muscle Injury and Repair
Frontiers in Cell and Developmental Biology, 2022 Skeletal muscle is essential to physical activity and energy metabolism. Maintaining intact functions of skeletal muscle is crucial to health and wellbeing.
Xingyu Wang, Lan Zhou
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The Skeletal Muscle Satellite Cell [PDF]
Journal of Histochemistry & Cytochemistry, 2011 The skeletal muscle satellite cell was first described and named based on its anatomic location between the myofiber plasma and basement membranes. In 1961, two independent studies by Alexander Mauro and Bernard Katz provided the first electron microscopic descriptions of satellite cells in frog and rat muscles.
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HDAC4 Regulates Skeletal Muscle Regeneration via Soluble Factors
Frontiers in Physiology, 2018 Skeletal muscle possesses a high ability to regenerate after an insult or in pathological conditions, relying on satellite cells, the skeletal muscle stem cells.
Alessandra Renzini +5 more
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Functional crosstalk of PGC-1 coactivators and inflammation in skeletal muscle pathophysiology [PDF]
, 2014 Skeletal muscle is an organ involved in whole body movement and energy metabolism with the ability to dynamically adapt to different states of (dis-)use.
Handschin, Christoph, Eisele, Petra S.
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Functional Overload Enhances Satellite Cell Properties in Skeletal Muscle
Stem Cells International, 2016 Skeletal muscle represents a plentiful and accessible source of adult stem cells. Skeletal-muscle-derived stem cells, termed satellite cells, play essential roles in postnatal growth, maintenance, repair, and regeneration of skeletal muscle.
Shin Fujimaki +5 more
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European Journal of Translational Myology, 2022 Neuromuscular disorders are a heterogeneous group of acquired or hereditary conditions that affect striated muscle function. The resulting decrease in muscle strength and motility irreversibly impacts quality of life.
Massimo Ganassi, Peter S. Zammit
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Transplantation to study satellite cell heterogeneity in skeletal muscle
Frontiers in Cell and Developmental Biology, 2022 Skeletal muscle has a remarkable capacity to regenerate throughout life, which is mediated by its resident muscle stem cells, also called satellite cells. Satellite cells, located periphery to the muscle fibers and underneath the basal lamina, are an indispensable cellular source for muscle regeneration. Satellite cell transplantation into regenerating
Bahareh Hekmatnejad +3 more
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Skeletal muscle mTORC1 regulates whole-body metabolism [PDF]
, 2015 Skeletal muscle, which represents over 40% of the total body mass, is a dynamic tissue with a key role in the maintenance of metabolic homeostasis. Several lines of evidence indicate that alterations of the normal muscle function, as for example in ...
Ormazabal, Maitea Guridi
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PLoS ONE, 2012 Skeletal muscle atrophy can occur as a consequence of immobilization and/or starvation in the majority of vertebrates studied. In contrast, hibernating mammals are protected against the loss of muscle mass despite long periods of inactivity and lack of ...
Eva Andres-Mateos +13 more
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Skeletal muscle in health and disease
Disease Models & Mechanisms, 2020 Skeletal muscle fibres are multinucleated cells that contain postmitotic nuclei (i.e. they are no longer able to divide) and perform muscle contraction.
Jennifer Morgan, Terence Partridge
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