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Contribution of stem cells to skeletal muscle regeneration.
Stem cells for skeletal muscle originate from dermomyotome of the embryo. The early marker of these cells is expression of both transcription factors Pax3 and Pax7 (Pax3+/Pax7+ cells).
Jerzy Moraczewski +8 more
doaj +1 more source
Post-transcriptional regulation of satellite cell quiescence by TTP-mediated mRNA decay. [PDF]
Skeletal muscle satellite cells in their niche are quiescent and upon muscle injury, exit quiescence, proliferate to repair muscle tissue, and self-renew to replenish the satellite cell population.
Blackshear, Perry J +7 more
core +2 more sources
Chemotaxis of skeletal muscle satellite cells [PDF]
Migration of myogenic cells occurs extensively during both embryogenesis and regeneration of skeletal muscle and is important in myoblast gene therapy, but little is known about factors that promote chemotaxis of these cells. We have used satellite cells from adult rats purified by Percoll density gradient centrifugation to test growth factors and ...
openaire +2 more sources
Estrogens maintain skeletal muscle and satellite cell functions [PDF]
Estrogens have crucial roles in an extensive range of physiological functions regulating cellular proliferation and differentiation, development, homeostasis, and metabolism. Therefore, prolonged estrogen insufficiency influences various types of tissues expressing estrogen receptors (ERs).
Yuriko, Kitajima, Yusuke, Ono
openaire +2 more sources
Isolation, characterization, and molecular regulation of muscle stem cells
keletal muscle has great regenerative capacity which is dependent on muscle stem cells, also known as satellite cells. A loss of satellite cells and/or their function impairs skeletal muscle regeneration and leads to a loss of skeletal muscle power ...
So-ichiro eFukada +5 more
doaj +1 more source
A Poglut1 mutation causes a muscular dystrophy with reduced Notch signaling and satellite cell loss [PDF]
Skeletal muscle regeneration by muscle satellite cells is a physiological mechanism activated upon muscle damage and regulated by Notch signaling. In a family with autosomal recessive limbgirdle muscular dystrophy, we identified a missense mutation in ...
Cabrera Serrano, Macarena +5 more
core +1 more source
Following skeletal muscle injury, muscle stem cells (satellite cells) are activated, proliferate, and differentiate to form myofibers. We show that mRNA-decay protein AUF1 regulates satellite cell function through targeted degradation of specific mRNAs ...
Devon M. Chenette +6 more
doaj +1 more source
Macrophage-released ADAMTS1 promotes muscle stem cell activation. [PDF]
Coordinated activation of muscle stem cells (known as satellite cells) is critical for postnatal muscle growth and regeneration. The muscle stem cell niche is central for regulating the activation state of satellite cells, but the specific extracellular ...
Aggarwal, Abhishek +7 more
core +2 more sources
An Overview about the Biology of Skeletal Muscle Satellite Cells
The peculiar ability of skeletal muscle tissue to operate adaptive changes during post-natal de-velopment and adulthood has been associated with the existence of adult somatic stem cells.
Laura Forcina +3 more
semanticscholar +1 more source
Skeletal muscle satellite cells (SCs) are adult muscle stem cells responsible for muscle regeneration after acute or chronic injuries. The lineage progression of quiescent SC toward activation, proliferation, and differentiation during the regeneration ...
Fengyuan Chen +14 more
semanticscholar +1 more source

