Results 31 to 40 of about 96,705 (260)
Isolation, characterization, and molecular regulation of muscle stem cells
Frontiers in Physiology, 2013 keletal muscle has great regenerative capacity which is dependent on muscle stem cells, also known as satellite cells. A loss of satellite cells and/or their function impairs skeletal muscle regeneration and leads to a loss of skeletal muscle power ...
So-ichiro eFukada +5 more
doaj +1 more source
Cell Reports, 2016 Following skeletal muscle injury, muscle stem cells (satellite cells) are activated, proliferate, and differentiate to form myofibers. We show that mRNA-decay protein AUF1 regulates satellite cell function through targeted degradation of specific mRNAs ...
Devon M. Chenette +6 more
doaj +1 more source
Somatic mutagenesis in satellite cells associates with human skeletal muscle aging
Nature Communications, 2018 Human aging is associated with a decline in skeletal muscle (SkM) function and a reduction in the number and activity of satellite cells (SCs), the resident stem cells.
Irene Franco +13 more
semanticscholar +1 more source
The Many Roles of Macrophages in Skeletal Muscle Injury and Repair
Frontiers in Cell and Developmental Biology, 2022 Skeletal muscle is essential to physical activity and energy metabolism. Maintaining intact functions of skeletal muscle is crucial to health and wellbeing.
Xingyu Wang, Lan Zhou
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Molecular Regulation and Rejuvenation of Muscle Stem (Satellite) Cell Aging
Indonesian Biomedical Journal, 2015 BACKGROUND: Age-related muscle loss leads to lack of muscle strength, resulting in reduced posture and mobility and an increased risk of falls, all of which contribute to a decrease in quality of life.
Anna Meiliana +2 more
doaj +1 more source
Aging Cell, 2019 Epigenetic alterations occur in various cells and tissues during aging, but it is not known if such alterations are also associated with aging in skeletal muscle.
Jiajian Zhou +13 more
semanticscholar +1 more source
Contribution of muscle satellite cells to sarcopenia
Frontiers in Physiology, 2022 Sarcopenia, a disorder characterized by age-related muscle loss and reduced muscle strength, is associated with decreased individual independence and quality of life, as well as a high risk of death.
Fengjiao Huo, Qing Liu, Hailiang Liu
semanticscholar +1 more source
Functional Overload Enhances Satellite Cell Properties in Skeletal Muscle
Stem Cells International, 2016 Skeletal muscle represents a plentiful and accessible source of adult stem cells. Skeletal-muscle-derived stem cells, termed satellite cells, play essential roles in postnatal growth, maintenance, repair, and regeneration of skeletal muscle.
Shin Fujimaki +5 more
doaj +1 more source
HDAC4 Regulates Skeletal Muscle Regeneration via Soluble Factors
Frontiers in Physiology, 2018 Skeletal muscle possesses a high ability to regenerate after an insult or in pathological conditions, relying on satellite cells, the skeletal muscle stem cells.
Alessandra Renzini +5 more
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Lsd1 regulates skeletal muscle regeneration and directs the fate of satellite cells
Nature Communications, 2018 Satellite cells are muscle stem cells required for muscle regeneration upon damage. Of note, satellite cells are bipotent and have the capacity to differentiate not only into skeletal myocytes, but also into brown adipocytes.
Milica Tošić +6 more
semanticscholar +1 more source