Results 41 to 50 of about 120,121 (346)
The Many Roles of Macrophages in Skeletal Muscle Injury and Repair
Frontiers in Cell and Developmental Biology, 2022 Skeletal muscle is essential to physical activity and energy metabolism. Maintaining intact functions of skeletal muscle is crucial to health and wellbeing.
Xingyu Wang, Lan Zhou
doaj +1 more source
Somatic mutagenesis in satellite cells associates with human skeletal muscle aging
Nature Communications, 2018 Human aging is associated with a decline in skeletal muscle (SkM) function and a reduction in the number and activity of satellite cells (SCs), the resident stem cells.
Irene Franco +13 more
semanticscholar +1 more source
Skeletal muscle satellite cells cultured in simulated microgravity [PDF]
In Vitro Cellular & Developmental Biology - Animal, 1997 Satellite cells are postnatal myoblasts responsible for providing additional nuclei to growing or regenerating muscle cells. Satellite cells retain the capacity to proliferate and differentiate in vitro and, therefore, provide a useful model to study postnatal muscle development.
G, Molnar +3 more
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HDAC4 regulates satellite cell proliferation and differentiation by targeting P21 and Sharp1 genes [PDF]
, 2018 Skeletal muscle exhibits a high regenerative capacity, mainly due to the ability of satellite cells to replicate and differentiate in response to appropriate stimuli. Epigenetic control is effective at different stages of this process.
Adamo, Sergio +9 more
core +2 more sources
Satellite cell proliferation and skeletal muscle hypertrophy [PDF]
Applied Physiology, Nutrition, and Metabolism, 2006 Satellite cells are small, mononuclear cells found in close association with striated skeletal muscles cells (myofibers). These cells appear to function as reserve myoblasts. A critical role for these cells in the process of muscle regeneration following injury has been clearly established.
openaire +4 more sources
The effect of calorie restriction on mouse skeletal muscle is sex, strain and time-dependent [PDF]
, 2017 Loss of skeletal muscle mass and function occurs with increasing age. Calorie restriction (CR) increases the lifespan of C57Bl/6 mice, but not in the shorter-lived DBA/2 strain.
Beaver, C +7 more
core +1 more source
Aging Cell, 2019 Epigenetic alterations occur in various cells and tissues during aging, but it is not known if such alterations are also associated with aging in skeletal muscle.
Jiajian Zhou +13 more
semanticscholar +1 more source
Epigenetic reprogramming of muscle progenitors: inspiration for clinical therapies [PDF]
, 2015 In the context of regenerative medicine, based on the potential of stem cells to restore diseased tissues, epigenetics is becoming a pivotal area of interest.
Consalvi, Silvia +2 more
core +9 more sources
New insights into the epigenetic control of satellite cells [PDF]
, 2015 Epigenetics finely tunes gene expression at a functional level without modifying the DNA sequence, thereby contributing to the complexity of genomic regulation.
Adamo, Sergio +2 more
core +1 more source
Contribution of muscle satellite cells to sarcopenia
Frontiers in Physiology, 2022 Sarcopenia, a disorder characterized by age-related muscle loss and reduced muscle strength, is associated with decreased individual independence and quality of life, as well as a high risk of death.
Fengjiao Huo, Qing Liu, Hailiang Liu
semanticscholar +1 more source