Results 41 to 50 of about 96,705 (260)

Factors Regulating or Regulated by Myogenic Regulatory Factors in Skeletal Muscle Stem Cells

Cells, 2022
MyoD, Myf5, myogenin, and MRF4 (also known as Myf6 or herculin) are myogenic regulatory factors (MRFs). MRFs are regarded as master transcription factors that are upregulated during myogenesis and influence stem cells to differentiate into myogenic ...
Tomohiko Shirakawa, T. Toyono, Asako Inoue, T. Matsubara, Tatsuo Kawamoto, S. Kokabu   +5 more
semanticscholar   +1 more source

Impaired skeletal muscle regeneration in the absence of fibrosis during hibernation in 13-lined ground squirrels.

PLoS ONE, 2012
Skeletal muscle atrophy can occur as a consequence of immobilization and/or starvation in the majority of vertebrates studied. In contrast, hibernating mammals are protected against the loss of muscle mass despite long periods of inactivity and lack of ...
Eva Andres-Mateos, Rebeca Mejias, Arshia Soleimani, Brian M Lin, Tyesha N Burks, Ruth Marx, Benjamin Lin, Richard C Zellars, Yonggang Zhang, David L Huso, Tom G Marr, Leslie A Leinwand, Dana K Merriman, Ronald D Cohn   +13 more
doaj   +1 more source

Skeletal muscle in health and disease

Disease Models & Mechanisms, 2020
Skeletal muscle fibres are multinucleated cells that contain postmitotic nuclei (i.e. they are no longer able to divide) and perform muscle contraction.
Jennifer Morgan, Terence Partridge
doaj   +1 more source

Involvement of muscle satellite cell dysfunction in neuromuscular disorders: Expanding the portfolio of satellite cell-opathies

European Journal of Translational Myology, 2022
Neuromuscular disorders are a heterogeneous group of acquired or hereditary conditions that affect striated muscle function. The resulting decrease in muscle strength and motility irreversibly impacts quality of life.
Massimo Ganassi, Peter S. Zammit
doaj   +1 more source

Regeneration competent satellite cell niches in rat engineered skeletal muscle

FASEB BioAdvances, 2019
Satellite cells reside in defined niches and are activated upon skeletal muscle injury to facilitate regeneration. Mechanistic studies of skeletal muscle regeneration are hampered by the inability to faithfully simulate satellite cell biology in vitro ...
Malte Tiburcy, Alex Markov, Lena K. Kraemer, Peter Christalla, Margret Rave‐Fraenk, Henrike J. Fischer, Holger M. Reichardt, Wolfram‐Hubertus Zimmermann   +7 more
doaj   +1 more source

Roles of nonmyogenic mesenchymal progenitors in pathogenesis and regeneration of skeletal muscle

Frontiers in Physiology, 2014
Adult skeletal muscle possesses a remarkable regenerative ability that is dependent on satellite cells. However, skeletal muscle is replaced by fatty and fibrous connective tissue in several pathological conditions.
Akiyoshi eUezumi, Madoka eIkemoto-Uezumi, Kunihiro eTsuchida   +2 more
doaj   +1 more source

Atrophic skeletal muscle fibre‐derived small extracellular vesicle miR‐690 inhibits satellite cell differentiation during ageing

Journal of Cachexia, Sarcopenia and Muscle, 2022
Sarcopenia is a common and progressive skeletal muscle disorder characterized by atrophic muscle fibres and contractile dysfunction. Accumulating evidence shows that the number and function of satellite cells (SCs) decline and become impaired during ...
Xiaoyan Shao, Wang Gong, Qianjin Wang, Pu Wang, T. Shi, Abdurahman Mahmut, Jianghui Qin, Yao Yao, Wenjin Yan, Dongyang Chen, Xiang Chen, Q. Jiang, Baosheng Guo   +12 more
semanticscholar   +1 more source

Established cell surface markers efficiently isolate highly overlapping populations of skeletal muscle satellite cells by fluorescence-activated cell sorting

Skeletal Muscle, 2016
Fluorescent-activated cell sorting (FACS) has enabled the direct isolation of highly enriched skeletal muscle stem cell, or satellite cell, populations from postnatal tissue.
C. Maesner, A. E. Almada, A. Wagers
semanticscholar   +1 more source

Long Noncoding Ribonucleic Acid MSTRG.59589 Promotes Porcine Skeletal Muscle Satellite Cells Differentiation by Enhancing the Function of PALLD

Frontiers in Genetics, 2019
Skeletal muscle satellite cells are a class of undifferentiated mononuclear myogenic stem cells distributed between the myofibroblast and membrane basement.
Long Li, Xiaofang Cheng, Ling Chen, Jingxuan Li, Wenzhe Luo, Changchun Li, Changchun Li   +6 more
doaj   +1 more source

Skeletal muscle satellite cells are located at a closer proximity to capillaries in healthy young compared with older men

Journal of Cachexia, Sarcopenia and Muscle, 2016
Skeletal muscle satellite cells (SC) are instrumental in maintenance of muscle fibres, the adaptive responses to exercise, and there is an age‐related decline in SC. A spatial relationship exists between SC and muscle fibre capillaries.
J. Nederveen, S. Joanisse, T. Snijders, V. Ivankovic, S. Baker, Stuart M Phillips, G. Parise   +6 more
semanticscholar   +1 more source