Results 61 to 70 of about 96,705 (260)

Stability of Medicinal Nanoemulsions to Spaceflight: Insights From the StarMed Experiment

Advanced Healthcare Materials, EarlyView.
Chitosan‐coated melatonin nanoemulsions (MN) recovered from a sounding rocket mission preserve droplet size and controlled‐release behavior, whereas uncoated nanoemulsions show ageing‐driven droplet growth and increased accessible drug fraction. Simple polymer coatings thus enhance the flight resilience of liquid space medicines under cumulative launch
Modupe Adebowale, Nguyen Van Duc Long, Philip M. Williams, Jens Hauslage, Volker Hessel   +4 more
wiley   +1 more source

FOXP3+ T Cells Recruited to Sites of Sterile Skeletal Muscle Injury Regulate the Fate of Satellite Cells and Guide Effective Tissue Regeneration

PLoS ONE, 2015
Muscle injury induces a classical inflammatory response in which cells of the innate immune system rapidly invade the tissue. Macrophages are prominently involved in this response and required for proper healing, as they are known to be important for ...
A. Castiglioni, Gianfranca Corna, E. Rigamonti, V. Basso, M. Vezzoli, A. Monno, A. E. Almada, A. Mondino, A. Wagers, A. Manfredi, P. Rovere-Querini   +10 more
semanticscholar   +1 more source

Soft Skins With Reversible Thickness Morphing: Materials, Mechanisms, and Applications

Advanced Materials, EarlyView.
Evolution of electronic skin (e‐skin) technologies toward adaptive, multifunctional soft skins. Phase I highlights early rigid and discrete sensory interfaces. Phase II shows the transition toward flexible, stretchable, and large‐area e‐skin. Phase III captures the emergence of computational e‐skin.
Oliver Ozioko, Chiamaka Akah, Ravinder Dahiya   +2 more
wiley   +1 more source

Combined Notch and PDGF Signaling Enhances Migration and Expression of Stem Cell Markers while Inducing Perivascular Cell Features in Muscle Satellite Cells

Stem Cell Reports, 2019
Summary: Satellite cells are responsible for skeletal muscle regeneration. Upon activation, they proliferate as transient amplifying myoblasts, most of which fuse into regenerating myofibers.
Mattia Francesco Maria Gerli, Louise Anne Moyle, Sara Benedetti, Giulia Ferrari, Ekin Ucuncu, Martina Ragazzi, Chrystalla Constantinou, Irene Louca, Hiroshi Sakai, Pierpaolo Ala, Paolo De Coppi, Shahragim Tajbakhsh, Giulio Cossu, Francesco Saverio Tedesco   +13 more
doaj   +1 more source

The role and therapeutic potential of stem cells in skeletal muscle in sarcopenia

Stem cell research & therapeutics, 2022
Sarcopenia is a common age-related skeletal muscle disorder featuring the loss of muscle mass and function. In regard to tissue repair in the human body, scientists always consider the use of stem cells.
Zijun Cai, Di Liu, Yun-Tao Yang, W. Xie, Miao He, Dengjie Yu, Yuxiang Wu, Xiu-hua Wang, Wenfeng Xiao, Yusheng Li   +9 more
semanticscholar   +1 more source

From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures

Advanced Robotics Research, EarlyView.
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley   +1 more source

Mesenchymal Stromal Cell‐Mediated Intercellular Communication: Mapping the Interactome for Skeletal Muscle Homeostasis and Regeneration

Advanced Science, EarlyView.
Liu et al. define a systems‐level interactome of fibroadipogenic progenitor (FAP)‐mediated signaling in skeletal muscle by integrating single‐cell transcriptomics with FAP depletion‐based perturbation analysis. Functional interrogation using a conditioned media bioassay links predicted signaling to multicellular outcomes, establishing a framework to ...
Xingyu Liu, Edgar E. Perez Carbajal, Yih‐Chii Hwang, Sahil A. Mapkar, Benjamin W. Gilman, Sarah A. Bliss, Lam B. Tran, Kalgi T. Mehta, Jacob O. Banyasz, Ming Yu, Reynold R. Liu, Matthew N. Ly, Christapher S. Morrissey, Michael N. Wosczyna   +13 more
wiley   +1 more source

Estrogen Regulates the Satellite Cell Compartment in Females

Cell Reports, 2019
Summary: Skeletal muscle mass, strength, and regenerative capacity decline with age, with many measures showing a greater deterioration in females around the time estrogen levels decrease at menopause.
Brittany C. Collins, Robert W. Arpke, Alexie A. Larson, Cory W. Baumann, Ning Xie, Christine A. Cabelka, Nardina L. Nash, Hanna-Kaarina Juppi, Eija K. Laakkonen, Sarianna Sipilä, Vuokko Kovanen, Espen E. Spangenburg, Michael Kyba, Dawn A. Lowe   +13 more
doaj   +1 more source

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

Advanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma, Rui Guo, Dongfeng Niu, Yufei Song, Zhenyao Zhang, Xiangxi Meng, Lili Mao, Haifeng Huang, Hua Zhu, Zhi Yang, Teli Liu   +10 more
wiley   +1 more source

Globular adiponectin activates motility and regenerative traits of muscle satellite cells. [PDF]

PLoS ONE, 2012
Regeneration of adult injured skeletal muscle is due to activation of satellite cells, a population of stem cells resident beneath the basal lamina. Thus, information on soluble factors affecting satellite cell activation, as well as migration towards ...
Tania Fiaschi, Elisa Giannoni, Maria Letizia Taddei, Paola Chiarugi   +3 more
doaj   +1 more source