Results 71 to 80 of about 120,121 (346)
Skeletal Muscle, 2016 Fluorescent-activated cell sorting (FACS) has enabled the direct isolation of highly enriched skeletal muscle stem cell, or satellite cell, populations from postnatal tissue.
C. Maesner, A. E. Almada, A. Wagers
semanticscholar +1 more source
Satellite cells from dystrophic muscle retain regenerative capacity
Stem Cell Research, 2015 Duchenne muscular dystrophy is an inherited disorder that is characterized by progressive skeletal muscle weakness and wasting, with a failure of muscle maintenance/repair mediated by satellite cells (muscle stem cells).
Luisa Boldrin +2 more
doaj +1 more source
Regenerative function of immune system: Modulation of muscle stem cells [PDF]
Ageing is characterised by progressive deterioration of physiological systems and the loss of skeletal muscle mass is one of the most recognisable, leading to muscle weakness and mobility impairments.
Al-Dabbagh, S +4 more
core +1 more source
Journal of Cachexia, Sarcopenia and Muscle, 2016 Skeletal muscle satellite cells (SC) are instrumental in maintenance of muscle fibres, the adaptive responses to exercise, and there is an age‐related decline in SC. A spatial relationship exists between SC and muscle fibre capillaries.
J. Nederveen +6 more
semanticscholar +1 more source
Epigenetic regulation of satellite cell fate during skeletal muscle regeneration
Skeletal Muscle, 2021 In response to muscle injury, muscle stem cells integrate environmental cues in the damaged tissue to mediate regeneration. These environmental cues are tightly regulated to ensure expansion of muscle stem cell population to repair the damaged myofibers ...
Jimmy Massenet +3 more
semanticscholar +1 more source
Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction
Advanced Healthcare Materials, EarlyView.Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang +4 more
wiley +1 more source
Journal of Cachexia, Sarcopenia and Muscle, 2022 Sarcopenia is a common and progressive skeletal muscle disorder characterized by atrophic muscle fibres and contractile dysfunction. Accumulating evidence shows that the number and function of satellite cells (SCs) decline and become impaired during ...
Xiaoyan Shao +12 more
semanticscholar +1 more source
3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence
Advanced Healthcare Materials, EarlyView.Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes +11 more
wiley +1 more source
Extrinsic Regulation of Satellite Cell Function and Muscle Regeneration Capacity during Aging [PDF]
, 2014 Optimal regeneration of skeletal muscle in response to injury requires the contribution of tissue resident stem cells termed satellite cells. Normally residing at the interface between the muscle fiber and overlying basal lamina it is generally ...
Brack, AS, Chakkalakal, JV
core +1 more source
Fusion and beyond: Satellite cell contributions to loading‐induced skeletal muscle adaptation
The FASEB Journal, 2021 Satellite cells support adult skeletal muscle fiber adaptations to loading in numerous ways. The fusion of satellite cells, driven by cell‐autonomous and/or extrinsic factors, contributes new myonuclei to muscle fibers, associates with load‐induced ...
Kevin A. Murach +4 more
semanticscholar +1 more source