Results 91 to 100 of about 19,858 (214)
Aquaculture ReportsThe SB203580 inhibitor, a blocker of the p38MAPK pathway, has been widely studied for bioimmune applications. To investigate its immune effect of Vibrio parahaemolyticus on Pinctada fucata martensii, the key genes, PmMKK6 and PmCREB, downstream of the ...
Jie Chen +4 more
doaj +1 more source
SB203580 does not reduce DENV production in DENV-infected mice.
, 2016 Mice were infected with 4 × 105 FFU/ml of DENV and treated with 2%DMSO alone or SB203580 in 2%DMSO. The uninfected control group was also treated with 2%DMSO.
Sansanee Noisakran (109150) +6 more
core +1 more source
Role of Autophagy on Cobrotoxin Induced Cell Death of A549
Chinese Journal of Lung Cancer, 2013 Background and objective It has been proven that cobrotoxin has anti-tumor effect while its role in lung cancer is rarely studied. The aim of this study is to assay the anti-tumor effect of cobrotoxin in cell line A549, and also to explore its possible ...
Jian SHEN +6 more
doaj +1 more source
In vitro modeling of COPD inflammation and limitation of p38 inhibitor — SB203580
International Journal of Chronic Obstructive Pulmonary Disease, 2016 Aihong Meng,1 Xiaopeng Zhang,2 Siyu Wu,1 Mingxia Wu,1 Jing Li,1 Xixin Yan,1 Kamilla Kopec-Harding,3 Jiakai Wu41Respiratory Division, The Second Hospital of Hebei Medical University, 2Department of Thoracic Surgery, Hebei Province General Hospital, Shijiazhuang, Hebei, Peoples’ Republic of China; 3Centre for Musculoskeletal Research, 4Centre ...
Meng,Aihong +7 more
openaire +3 more sources
, 2014 T84 cells and HAECs were treated with either TGF-beta and SIS3 (5 µM, A and C) or TGF-beta and SB203580 (10 µM, B and D) for 48 h prior to lysis and immunoblot for TMEM16A (A and C) or CFTR (B and D). For each cell type, the upper gel panels show TMEM16A
Yan Sanders (636855) +9 more
core +1 more source
SB203580 Enhances LPS-Induced G-CSF Production in Macrophages by Increasing G-CSF mRNA Stability
, 2013 顆粒性白血球群落刺激性因子 (Granulocyte colony-stimulating factor, G-CSF)是造血醣蛋白生長因子的成員之一，具有調控嗜中性白血球分化增生的能力。G-CSF可以經過LPS、IL-1β及TNF-α的刺激透過轉錄及後轉錄調控機制由內皮細胞、巨噬細胞及其他許多免疫細胞分泌。G-CSF mRNA三端未轉譯區 (3’ untranslated region, 3’UTR) 含有數個AUUUA序列 (adenosine uridine-rich elements, ARE)
Tsai, Wen-Ju, 蔡雯茹
core
Rosiglitazone and SB203580 attenuated activation of fibroblast motility induced by TGF-β1.
, 2014 Stimulation with TGF-β1 significantly improved the fibroblast motility compared with control group (p0.05). Cells were seeded in six-well plates, and scratch wounds were performed.
Xiao-Jian Guo (619451) +4 more
core +1 more source
p38 Mitogen-Activated Protein Kinase Regulates Vasoconstriction in Spontaneously Hypertensive Rats
Journal of Pharmacological Sciences, 2004 We investigated whether p42/p44 mitogen-activated protein kinase (MAPK) and/or p38 MAPK participates in the regulation of vascular smooth muscle contraction by endothelin-1 (ET-1) in Wistar-Kyoto rat (WKY) and spontaneously hypertensive rat (SHR).
Seongchun Kwon +5 more
doaj +1 more source
, 2014 (A) Effect of MS combined with the p38 inhibitor SB203580 on AGC gene expression at different concentrations (10, 20 µM). (B) Effect of the p38 inhibitor SB203580 on Col2 gene expression.
Suguru Shioji (670607) +4 more
core +1 more source
The efficacy and potential mechanism of cnidium lactone to inhibit osteoclast differentiation
Artificial Cells, Nanomedicine, and Biotechnology, 2019 Cnidium lactone is effective in the maintenance of bone mass in various osteoporosis models; however, the precise molecular mechanisms are not understood.
Jun-Yang Liang +3 more
doaj +1 more source