Results 121 to 130 of about 19,858 (214)

Treatment with p38 MAPK inhibitor (SB203580) inhibits EV71 replication at the viral protein synthesis stage.

, 2015
(A) Mock-infected RD cells were treated with SB203580 at different concentrations (10, 25, 50 and 100μM) or 1.0% DMSO (negative control) and cell lysates were harvested for Western blotting at 6h post-treatment. β-actin was included as a loading control.
Bryan Kit Teck Ong (699835), Shi Yun Leong (699834), Justin Jang Hann Chu (128668)   +2 more
core   +1 more source

Administration of the p38 MAPK inhibitor SB203580 affords brain protection with a wide therapeutic window against focal ischemic insult

, 2017
We have reported previously the delayed and differential induction of p38α and p38β mitogen-activated protein kinases (MAPKs) in microglia and astrocytes, respectively, in brain after transient global ischemia.
한평림
core   +1 more source

Dynamics in the p38α MAP Kinase–SB203580 Complex Observed by Liquid‐State NMR Spectroscopy

Angewandte Chemie International Edition, 2008
Honndorf, Valerie S., Coudevylle, Nicolas, Laufer, Stefan, Becker, Stefan, Griesinger, Christian   +4 more
openaire   +6 more sources

Selective inhibition of aldosterone production modulates human adrenocortical (HAC15) cell fate. [PDF]

Front Endocrinol (Lausanne)
Long KC, Aminuddin A, Ajlaa Ayub N, Tan GC, Jamal ARA, Abdul Murad NA, Johdi NA, Gomez-Sanchez CE, Sukor N, Brown MJ, Azizan EA.   +10 more
europepmc   +1 more source

Interleukin-24 Induces Inflammatory Chemokine and Cytokine Responses in Fibroblast-Enriched Synovial Cells from Patients with Knee Osteoarthritis. [PDF]

Biomedicines
Uekusa Y, Uchida K, Itakura M, Shibata N, Mukai M, Iwase D, Aikawa J, Tsukada A, Metoki Y, Inoue G, Takaso M.   +10 more
europepmc   +1 more source

NF-KappaB65380;p38 MAPK和JNK通路在运动神经损伤 引起的大鼠病理性疼痛中的作用及机制

Zhongshan Daxue xuebao. Yixue kexue ban, 2009
【目的】 探讨肿瘤坏死因子α(TNF-α)激活的下游信号转导途径-核转录因子kappaB (NF-κB)65380; JNK和p38 MAPK是否参与运动神经损伤引起的大鼠病理性疼痛的形成,并探讨其可能机制65377;【方法】 采用痛行为学测试和免疫荧光组织化学方法,观察鞘内注射NF-κB 抑制剂(PDTC)65380; p38 MAPK 抑制剂(SB203580)和JNK 抑制剂(SP600125)对腰5脊神经前根切断(L5-VRT)大鼠机械性痛过敏及腰5背根神经节(DRG)内电压门控钠通道(Nav1.
doaj  

Mechanistic insights into lipoprotein(a)-induced cardiomyocyte ferroptosis via ROS/p38/p53 signaling. [PDF]

Front Med (Lausanne)
Li Y, Chen X, He C, Zhang Y, Jiang T.
europepmc   +1 more source

α-Viniferin Induces Intrinsic Apoptosis in Triple-Negative Breast Cancer Cells and Synergizes With SB203580 Independently of p38 Mitogen-Activated Protein Kinase. [PDF]

J Breast Cancer
Kim DG, Kim G, Kim JY, Jang SK, Kim H, Jin HO, Seong MK, Park CS, Park IC, Kim HA.   +9 more
europepmc   +1 more source

Trichinella spiralis galectin disrupts gut epithelial integrity and mediates larval invasion via acting MUC13- ROCK2/MAPK pathway. [PDF]

PLoS Negl Trop Dis
Zhang R, Zhang Y, Zhang XZ, Cong PK, Wu JY, Long SR, Liu RD, Xu J, Cui J, Wang ZQ.   +9 more
europepmc   +1 more source

Alantolactone Activates the Extracellular Signal-Regulated Kinase Signaling Pathway to Promote Tumor Necrosis Factor Receptor 1 Ectodomain Shedding. [PDF]

Molecules
Yarangsee P, Vu QV, Miyake Y, Kataoka T.
europepmc   +1 more source