Results 11 to 20 of about 1,083 (143)

Higher order scaffoldin assembly in Ruminococcus flavefaciens cellulosome is coordinated by a discrete cohesin-dockerin interaction

Scientific Reports, 2018
Cellulosomes are highly sophisticated molecular nanomachines that participate in the deconstruction of complex polysaccharides, notably cellulose and hemicellulose.
Pedro Bule, Virgínia M. R. Pires, Victor D. Alves, Ana Luísa Carvalho, José A. M. Prates, Luís M. A. Ferreira, Steven P. Smith, Harry J. Gilbert, Ilit Noach, Edward A. Bayer, Shabir Najmudin, Carlos M. G. A. Fontes   +11 more
doaj   +2 more sources

A genomic analysis reveals the diversity of cellulosome displaying bacteria [PDF]

Frontiers in Microbiology
IntroductionSeveral species of cellulolytic bacteria display cellulosomes, massive multi-cellulase containing complexes that degrade lignocellulosic plant biomass (LCB). A greater understanding of cellulosome structure and enzyme content could facilitate
Christine M. Minor, Christine M. Minor, Allen Takayesu, Allen Takayesu, Sung Min Ha, Lukasz Salwinski, Michael R. Sawaya, Matteo Pellegrini, Robert T. Clubb, Robert T. Clubb, Robert T. Clubb   +10 more
doaj   +2 more sources

Comparative Transcriptomics Reveals a Dual Role of the Epidermal Differentiation Complex in the Skin and the Oesophagus [PDF]

Experimental Dermatology, Volume 34, Issue 12, December 2025.
ABSTRACT The epidermal differentiation complex (EDC) is a cluster of genes implicated in the control of the skin barrier. However, some EDC genes are also expressed at high levels in the human oesophagus. To determine whether the expression of EDC genes in the oesophagus is evolutionarily conserved, we performed comparative transcriptomic analyses of ...
Attila Placido Sachslehner, Julia Lachner, Veronika Mlitz, Bahar Golabi, Claudia Hess, Wolfgang Sipos, Leopold Eckhart   +6 more
wiley   +2 more sources

Higher order scaffoldin assembly in Ruminococcus flavefaciens cellulosome is coordinated by a discrete cohesin-dockerin interaction [PDF]

, 2018
\ua9 2018 The Author(s). Cellulosomes are highly sophisticated molecular nanomachines that participate in the deconstruction of complex polysaccharides, notably cellulose and hemicellulose.
Pires VMR, Carvalho AL, Fontes CMGA, Smith SP, Gilbert HJ, Prates JAM, Najmudin S, Alves VD, Noach I, Ferreira LMA, Bayer EA, Bule P   +11 more
core   +4 more sources

Computer‐based scaffoldings influence students' metacognitive monitoring and problem‐solving efficiency in an intelligent tutoring system

Journal of Computer Assisted Learning, Volume 39, Issue 5, Page 1652-1665, October 2023., 2023
Abstract Background Computer‐based scaffolding has been intensively used to facilitate students' self‐regulated learning (SRL). However, most previous studies investigated how computer‐based scaffoldings affected the cognitive aspect of SRL, such as knowledge gains and understanding levels. In contrast, more evidence is needed to examine the effects of
Tingting Wang, Juan Zheng, Chengyi Tan, Susanne P. Lajoie   +3 more
wiley   +1 more source

The trench dug for the bluff balustrade filled with scaffolding

, 2022
The trench dug for the bluff balustrade filled with ...

core   +6 more sources

Engineering and characterization of carbohydrate‐binding modules for imaging cellulose fibrils biosynthesis in plant protoplasts

Biotechnology and Bioengineering, Volume 120, Issue 8, Page 2253-2268, August 2023., 2023
Carbohydrate binding modules (CBMs) are noncatalytic domains that have been used to visualize distinct polysaccharides present in the plant cell wall. Here, engineered type‐A tandem CBMs have been characterized using pull‐down and kinetic assays.
Dharanidaran Jayachandran, Peter Smith, Mohammad Irfan, Junhong Sun, John M. Yarborough, Yannick J. Bomble, Eric Lam, Shishir P. S. Chundawat   +7 more
wiley   +1 more source

Synthetic Multienzyme Assemblies for Natural Product Biosynthesis

ChemBioChem, Volume 24, Issue 6, March 14, 2023., 2023
Constructing multienzyme complexes has become an effective way to optimize metabolic flux and increase the titer of natural products in metabolic engineering recently. In this review, we summarize strategies for constructing synthetic multienzyme complexes in microbial cells and their applications in promoting natural product biosynthesis.
Min Liu, Yue Wang, Hao Jiang, Yongxu Han, Jiang Xia   +4 more
wiley   +1 more source

Minimalistic Cellulosome of the Butanologenic Bacterium Clostridium saccharoperbutylacetonicum

mBio, 2020
Clostridium saccharoperbutylacetonicum is a mesophilic, anaerobic, butanol-producing bacterium, originally isolated from soil. It was recently reported that C. saccharoperbutylacetonicum possesses multiple cellulosomal elements and would potentially form
Bosmat Levi Hevroni, Sarah Moraïs, Yonit Ben-David, Ely Morag, Edward A. Bayer   +4 more
doaj   +1 more source

Current progress on engineering microbial strains and consortia for production of cellulosic butanol through consolidated bioprocessing

Microbial Biotechnology, Volume 16, Issue 2, Page 238-261, February 2023., 2023
Development of consolidated bioprocessing (CBP) of lignocellulose to butanol can potentially replace butanol production from non‐renewable sources at viable costs. Progress in CBP development has been obtained by combination of (hemi)cellulolytic and butanol‐producing features in a single strain (by metabolic engineering or protoplast fusion) or by ...
Angela Re, Roberto Mazzoli
wiley   +1 more source