Results 31 to 40 of about 8,394 (182)
Sugar Makes Fat by Talking to SCAP [PDF]
Cancer Cell, 2015 Elevated blood glucose promotes lipogenesis via activating SREBP transcription factors. Tumors exhibit increased glucose uptake and lipogenesis, but the mechanisms controlling this are poorly understood. In this issue of Cancer Cell, Cheng and colleagues find that glucose activates SREBP by stabilizing SCAP, a central regulator of the SREBP pathway.
Shao, Wei, Espenshade, Peter J.
openaire +2 more sources
NETosis is critical in patients with severe community-acquired pneumonia
Frontiers in Immunology, 2022 Pneumonia is the fourth leading cause of death globally, and the reason for the high mortality rate of patients with severe community-acquired pneumonia (SCAP) remains elusive.
Yiming Zhang +11 more
doaj +1 more source
Astronomy & Geophysics, 2000 Mike Bode, Phil Charles and Carlos Frenk report on a Standing Conference of Astronomy Professors meeting to consider the UK–ESO question, held at the Royal Astronomical Society on 22 June 2000.
openaire +1 more source
Stem Cell Research & Therapy, 2018 Background Stem cells from apical papilla (SCAP) are a subpopulation of mesenchymal stem cells (MSCs) isolated from the apical papilla of the developing tooth root apex of human teeth.
Yosuke Tanaka +10 more
doaj +1 more source
Stem Cell Research & Therapy, 2021 Objectives Recently, a new strategy has been developed to directly reprogram one cell type towards another targeted cell type using small molecule compounds.
Baicheng Yi +8 more
doaj +1 more source
SCAP-subalgebras of Lie algebras [PDF]
Czechoslovak Mathematical Journal, 2016 A subalgebra H of a finite dimensional Lie algebra L is said to be a SCAP-subalgebra if there is a chief series 0 = L 0 ⊂ L 1 ⊂... ⊂ L t = L of L such that for every i = 1, 2,..., t, we have H + L i = H + L
Sara Chehrazi, Ali Reza Salemkar
openaire +1 more source
Journal of Lipid Research, 2016 SREBP cleavage-activating protein (SCAP) is a key protein in the regulation of lipid metabolism and a potential target for treatment of dyslipidemia. SCAP is required for activation of the transcription factors SREBP-1 and -2.
Kristian K. Jensen +21 more
doaj +1 more source
Journal of the Formosan Medical Association, 2020 Background/Purpose: Basic fibroblast growth factor (bFGF) exhibits multiple biological functions in various tissues. Stem cells from apical papilla (SCAP) can be isolated from human apical papilla tissues in developmental teeth of children.
Mei-Chi Chang +7 more
doaj +1 more source
Frontiers in Genetics, 2020 Osteo/odontogenic differentiation is a key process of human stem cells from apical papilla (SCAP) in tooth root development. Emerging evidence indicates microRNAs (miRNAs) play diverse roles in osteogenesis.
Junqing Liu +9 more
doaj +1 more source
Scap is required for sterol synthesis and crypt growth in intestinal mucosa[S]
Journal of Lipid Research, 2015 SREBP cleavage-activating protein (Scap) is an endoplasmic reticulum membrane protein required for cleavage and activation of sterol regulatory element-binding proteins (SREBPs), which activate the transcription of genes in sterol and fatty acid ...
Matthew R. McFarlane +5 more
doaj +1 more source