Results 21 to 30 of about 11,276 (233)
Sugar Makes Fat by Talking to SCAP [PDF]
Elevated blood glucose promotes lipogenesis via activating SREBP transcription factors. Tumors exhibit increased glucose uptake and lipogenesis, but the mechanisms controlling this are poorly understood. In this issue of Cancer Cell, Cheng and colleagues find that glucose activates SREBP by stabilizing SCAP, a central regulator of the SREBP pathway.
Shao, Wei, Espenshade, Peter J.
openaire +2 more sources
A typical dataset consists of 16 instances ranging from 5 ORs with 40 cases to 30 ORs with 240 cases.
Lei Zhu (14188703)
core +1 more source
Chronological Order Rearranging of ‘Instructions' about the Company Financial Report by GHQ/SCAP : Through the Analysis of the GHQ/SCAP Records,Economic and Scientific Section (ESS) [PDF]
第二次世界大戦後,GHQ/SCAPは財閥解体の目的のため,日本の会社に対し英文財務諸表の提出を求め,その際,財務諸表の雛形を付した「指示書」を交付した。この「指示書」の種類や内容については,充分には解明されていない。本稿では,GHQ/SCAPの一部局である,ESSが作成した文書から当該「指示書」を選別し,時系列整理を行った。その結果,従来,存在が判明していた2種類の「指示書」以外に,新たに5種類の「指示書」の存在が判明した。After World War II, GHQ/SCAP demanded ...
3355 +2 more
core +1 more source
SCAP is required for timely and proper myelin membrane synthesis.
Myelination requires a massive increase in glial cell membrane synthesis. Here, we demonstrate that the acute phase of myelin lipid synthesis is regulated by sterol regulatory element-binding protein (SREBP) cleavage activation protein (SCAP), an ...
Kirschner, Daniel +17 more
core +3 more sources
Objectives Recently, a new strategy has been developed to directly reprogram one cell type towards another targeted cell type using small molecule compounds.
Baicheng Yi +8 more
doaj +1 more source
Background Stem cells from apical papilla (SCAP) are a subpopulation of mesenchymal stem cells (MSCs) isolated from the apical papilla of the developing tooth root apex of human teeth.
Yosuke Tanaka +10 more
doaj +1 more source
NETosis is critical in patients with severe community-acquired pneumonia
Pneumonia is the fourth leading cause of death globally, and the reason for the high mortality rate of patients with severe community-acquired pneumonia (SCAP) remains elusive.
Yiming Zhang +11 more
doaj +1 more source
The ER cholesterol sensor SCAP promotes CARTS biogenesis at ER–Golgi membrane contact sites [PDF]
In response to cholesterol deprivation, SCAP escorts SREBP transcription factors from the endoplasmic reticulum to the Golgi complex for their proteolytic activation, leading to gene expression for cholesterol synthesis and uptake.
Chiaki Watanabe +25 more
core +1 more source
SREBP cleavage-activating protein (SCAP) is a key protein in the regulation of lipid metabolism and a potential target for treatment of dyslipidemia. SCAP is required for activation of the transcription factors SREBP-1 and -2.
Kristian K. Jensen +21 more
doaj +1 more source

