Results 41 to 50 of about 11,276 (233)

Scap-Exo-Mediated Dspp Mrna Delivery Induces Bmmscs Specific Dentinogenesis

International Dental Journal
Aim or purpose: To investigate the use of exosomes derived from stem cells from apical papilla (SCAP-Exo) to deliver dentin sialophosphoprotein (DSPP) mRNA, promoting odontogenic differentiation of bone marrow mesenchymal stem cells (BMMSCs) and ...
Xueying Zhuang, Xu Chen
doaj   +1 more source

Unipolar Barrier Near‐Infrared 2D Photodetectors for 3D Image Sensors

Advanced Science, EarlyView.
A MoTe2/WSe2/Cl–SnSe2 unipolar barrier photodetector is demonstrated, in which the WSe2 layer effectively blocks majority‐carrier injection, yielding suppressed dark current and enhanced near‐infrared (NIR) sensing. The device achieves high detectivity, a wide linear dynamic range, and fast response under 1310 nm illumination, enabling high‐fidelity 3D
Jung Pyo Hong, Sang‐Jun Kim, Jisu Jang, Je‐Jun Lee, Seong‐Jun Han, Eungseon Yeon, Jung Woo Kim, Jongtae Ahn, Sang Yeon Kim, Hyun Woo Ko, Sunghyun Han, Seung Ah Lee, Paul Hongsuck Seo, Young‐Woo Suh, Kimoon Lee, Gunuk Wang, Dong‐Guang Zheng, Sunghee Hong, Sangin Hahn, Seon Kyu Yoon, Min‐Chul Park, Do Kyung Hwang   +21 more
wiley   +1 more source

Advances in Se Wide‐Bandgap Photovoltaics and TexSe1‐x SWIR Photodiodes

Advanced Science, EarlyView.
In this review, fundamental properties and current challenges in Se photovoltaics (PVs) for tandem and indoor PVs and TexSe1‐x alloys for short wave infrared photodiodes are discussed. A case is made for the practicality of elemental chalcogenide optoelectronics, and a pathway toward resolving the key challenges in these respective technologies is ...
Adam D. Alfieri, Deep Jariwala
wiley   +1 more source

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source

Scaps: type-directed API search for Scala [PDF]

Proceedings of the 2016 7th ACM SIGPLAN Symposium on Scala, 2016
Type-directed API search, using queries composed of both keywords and type signatures to retrieve definitions from APIs, are popular in the functional programming community. This search technique allows programmers to easily navigate complex and large APIs in order to find the definitions they are interested in.
Lukas Wegmann, Farhad Mehta, Peter Sommerlad, Mirko Stocker   +3 more
openaire   +1 more source

Optimized Cas9‐Enriched Nanopore Sequencing and Analysis Workflow for Clinical Diagnosis of Repeat Expansion Disorders

Advanced Science, EarlyView.
An optimized Cas9‐enriched nanopore sequencing workflow, combined with STRiker, enables simultaneous analysis of disease‐associated STR loci from patient blood. The nCATS–STRiker workflow detects repeat expansions, de novo repeat motifs, interruption patterns, and methylation in a single assay, improving the genetic diagnosis of previously undiagnosed ...
Seungbok Lee, Chanju Jung, Minjeong Kim, Narae Kim, Gue‐Ho Hwang, Soon‐Tae Lee, Kon Chu, Sang Kun Lee, Han‐Joon Kim, Jong‐Hee Chae, Sangsu Bae, Jangsup Moon   +11 more
wiley   +1 more source

miR-486-5p predicted adverse outcomes of SCAP and regulated K. pneumonia infection via FOXO1

BMC Immunology
Purpose Severe community-acquired pneumonia (SCAP) is a common respiratory system disease with rapid development and high mortality. Exploring effective biomarkers for early detection and development prediction of SCAP is of urgent need.
Qianqi Jin, Chuanlan Liu, Yan Cao, Feiyan Wang   +3 more
doaj   +1 more source

FTSJ3‐Mediated 2′‐O‐Methylation of HSPA5 mRNA Stabilizes BOP1 via SUMOylation to Drive DRP1‐Dependent Mitochondrial Fission and Fatty Acid Oxidation in Lung Squamous Cell Carcinoma

Advanced Science, EarlyView.
The RNA methyltransferase FTSJ3 drives lung squamous cell carcinoma progression by catalyzing 2′‐O‐methylation of HSPA5 mRNA, which stabilizes BOP1 through SUMOylation and activates DRP1/SREBP1‐mediated mitochondrial fission and fatty acid oxidation. Targeting this axis with liposomal siRNA potently suppresses tumor growth and metastasis ABSTRACT Lung ...
Qin Hu, Jiaheng Lin, Yifei Zhu, Ying Liu, Guoren Zhou   +4 more
wiley   +1 more source

SCAP - a Shaped Charge Analysis Program: user's manual for SCAP 1. 0 [PDF]

, 1985
The basic modeling and format for a shaped charge analysis program, SCAP, is described. The code models the motion of liner elements due to explosive loading, jet formation, jet breakup and target penetration through application of a series of analytical approximations.
openaire   +2 more sources

Mechanically Regulated Secretion: How Physical Forces Instruct the Secretory Pathway and Remodel the Secretome

Advanced Science, EarlyView.
Mechanical cues, including ECM stiffness, stretch, compression, shear stress, and traction forces, remodel trafficking across the secretory pathway, from the ER and Golgi to endolysosomal compartments and the plasma membrane. The resulting secretome reshapes ECM composition and tissue mechanics, establishing feedback loops that support homeostasis or ...
Domenico Russo, Seetharaman Parashuraman, Maria Luigia Maresca, Angela Francesca Dinoi, Alessia Calcagnì, Riccardo Rizzo   +5 more
wiley   +1 more source