Results 141 to 150 of about 2,493,460 (390)

Primary hepatocytes as targets for hepatitis C virus replication [PDF]

, 2008
Much of our current understanding of hepatitis C virus (HCV) replication has hailed from the use of a small number of cloned viral genomes and transformed hepatoma cell lines.
Agnello, Andre, Andreo, Bartenschlager, Bartosch, Bartosch, Bartosch, Basu, Bertaux, Castet, Catanese, Chang, Cocquerel, Codran, Decaens, Diaz, Dreux, Evans, Flint, Fournier, Furuse, Gastaminza, Grove, Harder, Harris, Hsu, Huang, Kanda, Kapadia, Krieger, Lazaro, Levy, Lindenbach, Lindenbach, Maillard, Martin, McCaughan, Mee, Meertens, Mercer, Meuleman, Meunier, Moghe, Molina, Molina, Morikawa, Nielsen, Nielsen, Olenina, Pileri, Prince, Reynolds, Scarselli, Silver, Thomssen, Timpe, Vinken, Voisset, Wakita, Wang, Wunschmann, Yang, Zeisel, Zhang, Zheng, Zhong   +65 more
core   +2 more sources

Homeostasis: A scavenger receptor for haemoglobin [PDF]

Current Biology, 2001
Recent studies have identified a macrophage-specific receptor for the clearance of haemoglobin-haptoglobin complexes, which protects the host against the toxicity of free haemoglobin.
openaire   +2 more sources

Shape‐Changing Multiphase Microparticles from Complex Liquid Crystal Emulsions

Advanced Functional Materials, EarlyView.
Liquid crystalline network (LCN) microparticles are prepared from single, double (Janus), and triple emulsions through a simple and scalable bulk‐emulsification strategy. Under heating, the particles exhibit robust, reversible, large‐amplitude deformations that depend both on the morphology and the liquid crystals director field configuration.
Marco Turriani, Camilla Parmeggiani, Daniele Martella, Alberto Concellón   +3 more
wiley   +1 more source

Characterization of Hepatitis C Virus Particle Subpopulations Reveals Multiple Usage of the Scavenger Receptor BI for Entry Steps*

Journal of Biological Chemistry, 2012
Background: SR-BI binds HCV E2 glycoprotein and lipoprotein components. Results: HCV entry exploits several SR-BI properties and different viral and cellular determinants present on the viral particles. Conclusion: SR-BI is a multifunctional entry factor
V. L. Dao Thi, Christelle Granier, M. Zeisel, M. Guerin, Jimmy Mancip, O. Granio, F. Penin, Dimitri Lavillette, R. Bartenschlager, T. Baumert, F. Cosset, M. Dreux   +11 more
semanticscholar   +1 more source

Expression of DC-SIGN and DC-SIGNR on human sinusoidal endothelium: a role for capturing hepatitis C virus particles. [PDF]

, 2006
Hepatic sinusoidal endothelial cells are unique among endothelial cells in their ability to internalize and process a diverse range of antigens. DC-SIGNR, a type 2 C-type lectin expressed on liver sinusoids, has been shown to bind with high affinity to ...
Adam Jennings, Alvarez, Appelmelk, Bartosch, Bashirova, Cormier, Cormier, Crispe, David H. Adams, Ebner, Engering, Feinberg, Flint, Gardner, Geijtenbeek, Grant, Guo, Halary, Hsu, Jameson, Jane A. McKeating, Jie Zhang, Klimstra, Knolle, Krutzik, Lalor, Lasala, Lee, Limmer, Lindenbach, Lindenbach, Lozach, Lozach, Lozach, Ludwig, Maeda, Marzi, McCully, Mitchell, Mukhtar, Patricia F. Lalor, Phoebe J. Sun, Pileri, Pohlmann, Pohlmann, Pohlmann, Pohlmann, Puig-Kroger, Relloso, Romani, Seternes, Simmons, Soilleux, Stefan Hubscher, Tassaneetrithep, Trumpfheller, Turville, Wai K. Lai, Wakita, Yang, Zhang, Zhong   +61 more
core   +2 more sources

Scavenger Receptors Class A-I/II and CD36 Are the Principal Receptors Responsible for the Uptake of Modified Low Density Lipoprotein Leading to Lipid Loading in Macrophages [PDF]

, 2002
Vidya Kunjathoor, Maria Febbraio, Eugene A. Podrez, Kathryn J. Moore, Lorna P. Andersson, Stephanie L. Koehn, Jeongmi S. Rhee, Roy L. Silverstein, Henry F. Hoff, Mason W. Freeman   +9 more
openalex   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Protective Effects of Human and Mouse Soluble Scavenger-Like CD6 Lymphocyte Receptor in a Lethal Model of Polymicrobial Sepsis [PDF]

, 2016
Mario Martínez‐Florensa, Marta Consuegra‐Fernández, Fernando Aranda, Noelia Armiger-Borràs, Marianna Di Scala, Esther Carrasco, Jerónimo Pachón, Jordi Vilà, Gloria González‐Aseguinolaza, Francisco Lozano   +9 more
openalex   +1 more source

Fluorescent Polymeric Nanofibers as Ratiometric Multiplexed Skin Sensors of pH and Oxygen

Advanced Healthcare Materials, EarlyView.
Fluorescent polymeric nanofibers and nanorods are produced as ratiometric sensors of two important physiological parameters: pH and oxygen. They operate by dual Forster resonance energy transfer from large number of energy donor dyes to limited number of two distinct energy acceptors, enabling simultaneous sensing of pH and oxygen.
Rémi Pelletier, Anila Hoskere Ashoka, Andrey S. Klymchenko   +2 more
wiley   +1 more source

The macrophage scavenger receptor at 30 years of age: current knowledge and future challenges

Journal of Lipid Research, 2009
It is now thirty years since the original observation that macrophages take up and degrade modified forms of low density lipoprotein (LDL). Molecular cloning has identified multiple scavenger receptors that can endocytose modified LDL and binding studies
David R. Greaves, Siamon Gordon
doaj   +1 more source