Results 31 to 40 of about 2,437,132 (390)

Innate immunity and neuroinflammation [PDF]

open access: yes, 2013
Copyright © 2013 Abhishek Shastri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Bonifati, DM, Kishore, U, Shastri, A
core   +3 more sources

Scavenger Receptors and Their Potential as Therapeutic Targets in the Treatment of Cardiovascular Disease

open access: yesInternational Journal of Hypertension, 2010
Scavenger receptors act as membrane-bound and soluble proteins that bind to macromolecular complexes and pathogens. This diverse supergroup of proteins mediates binding to modified lipoprotein particles which regulate the initiation and progression of ...
Sam L. Stephen   +7 more
doaj   +1 more source

Primary hepatocytes as targets for hepatitis C virus replication [PDF]

open access: yes, 2008
Much of our current understanding of hepatitis C virus (HCV) replication has hailed from the use of a small number of cloned viral genomes and transformed hepatoma cell lines.
Agnello   +65 more
core   +2 more sources

Scavenger receptor mediates systemic RNA interference in ticks. [PDF]

open access: yesPLoS ONE, 2011
RNA interference is an efficient method to silence gene and protein expressions. Here, the class B scavenger receptor CD36 (SRB) mediated the uptake of exogenous dsRNAs in the induction of the RNAi responses in ticks.
Kyaw Min Aung   +8 more
doaj   +1 more source

Protective Effects of Human and Mouse Soluble Scavenger-Like CD6 Lymphocyte Receptor in a Lethal Model of Polymicrobial Sepsis [PDF]

open access: yes, 2016
Sepsis still constitutes an unmet clinical need, which could benefit from novel adjunctive strategies to conventional antibiotic therapy. The soluble form of the scavenger-like human CD6 lymphocyte receptor (shCD6) binds to key pathogenic components from
Aranda, Fernando   +9 more
core   +1 more source

Hepatoma cell density promotes claudin-1 and scavenger receptor BI expression and hepatitis C virus internalization. [PDF]

open access: yes, 2009
Hepatitis C virus (HCV) entry occurs via a pH- and clathrin-dependent endocytic pathway and requires a number of cellular factors, including CD81, the tight-junction proteins claudin 1 (CLDN1) and occludin, and scavenger receptor class B member I (SR-BI).
Balfe, Peter   +5 more
core   +2 more sources

Deletion of the murine scavenger receptor CD68 [PDF]

open access: yesJournal of Lipid Research, 2011
Scavenger receptors (ScRs) are a structurally unrelated family of receptors with the ability to bind modified low density lipoprotein (LDL) as well as a broad range of polyanionic ligands. CD68, whose expression is restricted to mononuclear phagocytes, is a unique ScR family member, owing to its lysosome associated membrane protein (LAMP)-like domain ...
Song, Li   +2 more
openaire   +6 more sources

P2X7 as a scavenger receptor for innate phagocytosis in the brain

open access: yesBritish Journal of Pharmacology, 2018
The P2X7 receptor has been widely studied for its ATP‐induced pro‐inflammatory effect, but in the absence of a ligand, P2X7 has a second function as a scavenger receptor, which is active in the development of the human brain.
B. Gu, J. Wiley
semanticscholar   +1 more source

Apoptotic cell recognition receptors and scavenger receptors [PDF]

open access: yesImmunological Reviews, 2015
SummaryPhosphatidylserine recognition receptors are a highly diverse set of receptors grouped by their ability to recognize the ‘eat‐me’ signal phosphatidylserine on apoptotic cells. Most of the phosphatidylserine recognition receptors dampen inflammation by inducing the production of anti‐inflammatory mediators during the phagocytosis of apoptotic ...
Kristen K. Penberthy   +1 more
openaire   +3 more sources

Phagocytosis by macrophages depends on histamine H2 receptor signaling and scavenger receptor 1

open access: yesMicrobiologyOpen, 2019
The histamine H2 receptor (H2R) is a G protein‐coupled receptor that mediates cyclic AMP production, protein kinase A activation, and MAP kinase signaling.
Robert Fultz   +9 more
doaj   +1 more source

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