Results 31 to 40 of about 128,986 (306)

Phagocytosis by macrophages depends on histamine H2 receptor signaling and scavenger receptor 1

MicrobiologyOpen, 2019
The histamine H2 receptor (H2R) is a G protein‐coupled receptor that mediates cyclic AMP production, protein kinase A activation, and MAP kinase signaling.
Robert Fultz, Melinda A. Engevik, Zhongcheng Shi, Anne Hall, Beatrice Herrmann, Bhanu P. Ganesh, Angela Major, Anthony Haag, Yuko Mori‐Akiyama, James Versalovic   +9 more
doaj   +1 more source

Macrophage SR-BI regulates LPS-induced pro-inflammatory signaling in mice and isolated macrophages

Journal of Lipid Research, 2012
Scavenger receptor BI (SR-BI), an HDL receptor, plays a key role in reverse cholesterol transport. In mice, disruption of SR-BI results in hypersensitivity to lipopolysaccharide (LPS) and bacteria-induced septic shock due to adrenal insufficiency and ...
Lei Cai, Zhen Wang, Jason M. Meyer, Ailing Ji, Deneys R. van der Westhuyzen   +4 more
doaj   +1 more source

Hepatitis C virus relies on lipoproteins for its life cycle [PDF]

, 2016
Hepatitis C virus (HCV) infects over 150 million people worldwide. In most cases, HCV infection becomes chronic causing liver disease ranging from fibrosis to cirrhosis and hepatocellular carcinoma.
Alonzi, Tonino, DI CAPRIO, Giorgia, Fimia, Gian Maria, Grassi, Germana, Ippolito, Giuseppe, Tripodi, Marco   +5 more
core   +1 more source

Roles of reconstituted high-density lipoprotein nanoparticles in cardiovascular disease: A new paradigm for drug discovery [PDF]

, 2020
Epidemiological results revealed that there is an inverse correlation between high-density lipoprotein (HDL) cholesterol levels and risks of atherosclerotic cardiovascular disease (ASCVD).
Huang, Hui, Huang, Jiansheng, Huang, Li-Hao, Wang, Dongdong   +3 more
core   +2 more sources

Scavenger receptors in atherosclerosis [PDF]

Current Opinion in Hematology, 1997
Membership in the broad family of scavenger receptors has grown significantly. Two new scavenger receptor receptors have been cloned (SR-BI and SR-CI) and a previously isolated integral membrane protein (CD36) has been found to possess lipoprotein binding properties that entitle it to be included in the family. The breadth of ligand recognition of this
openaire   +2 more sources

Modulation of macrophage scavenger receptor transport by protein phosphorylation

Journal of Lipid Research, 1996
The identification of three highly conserved phosphorylation sites in the cytoplasmic domain of each of the monomeric subunits of the macrophage scavenger receptor suggests that protein phosphorylation may regulate this receptor pathway.
L G Fong
doaj   +1 more source

Tissue Levels of CD80, CD163 and CD206 and Their Ratios in Periodontal and Peri-Implant Health and Disease

Current Issues in Molecular Biology, 2022
This study aimed to compare tissue levels of CD80 (pro-inflammatory macrophage-related surface marker), CD163, and CD206 (anti-inflammatory macrophage-related surface markers), and their ratios in periodontal and peri-implant health and disease ...
Mustafa Yilmaz, Esra Demir, Yigit Firatli, Erhan Firatli, Ulvi Kahraman Gürsoy   +4 more
doaj   +1 more source

Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis [PDF]

, 2017
IgA nephropathy (IgAN) is the most prevalent among primary glomerular diseases worldwide. Although our understanding of IgAN has advanced significantly, its underlying biology and potential drug targets are still unexplored.
Cisek, Katryna, Delles, Christian, Filip, Szymon, Gakiopoulou, Chara, Jankowski, Joachim, Krochmal, Magdalena, Markoska, Katerina, Mischak, Harald, Orange, Clare, Spasovski, Goce, Vlahou, Antonia, Zoidakis, Jerome   +11 more
core   +2 more sources

Structures and high and low affinity ligand binding properties of murine type I and type II macrophage scavenger receptors

Journal of Lipid Research, 1993
Macrophage scavenger receptors have been implicated in various macrophage-associated processes, including atherosclerosis and clearance of bacterial endotoxin. They bind to a wide variety of polyanionic ligands and display complex binding characteristics.
J Ashkenas, M Penman, E Vasile, S Acton, M Freeman, M Krieger   +5 more
doaj   +1 more source

The hepatoadrenal syndrome: A common yet unrecognized clinical condition [PDF]

, 2005
Objective: Adrenal failure is common in critically ill patients, particularly those with sepsis. As liver failure and sepsis are both associated with increased circulating levels of endotoxin and proinflammatory mediators and reduced levels of apoprotein-
Acton, Ali, Annane, Annane, Baranova, Beishuizen, Borkowski, Calco, Cicognani, Cooper, Darlington, Davies, de la Llera-Moya, Dimopoulou, Eisenberg, Ettinger, Gordon, Hamrahian, Harry, Hinshaw, Jaattela, Kilger, Liu, Liu, Liu, Liu, Loriaux, Marik, Marik, Marik, Marik, Marik, McDonald, Melby, Miyata, Molijn, Molijn, Mookerjee, Paul E. Marik, Rasaratnam, Rivers, Scammell, Singh, Sun, Thomas E. Starzl, Timothy Gayowski, van der Voort, van Leeuwen, Vishnyakova, Yaguchi, Yokoyama, Yokoyama   +51 more
core   +1 more source