Results 31 to 40 of about 2,493,460 (390)

Hepatoma cell density promotes claudin-1 and scavenger receptor BI expression and hepatitis C virus internalization. [PDF]

, 2009
Hepatitis C virus (HCV) entry occurs via a pH- and clathrin-dependent endocytic pathway and requires a number of cellular factors, including CD81, the tight-junction proteins claudin 1 (CLDN1) and occludin, and scavenger receptor class B member I (SR-BI).
Balfe, Peter, Grove, Joe, Hu, Ke, McKeating, Jane A, Mee, Christopher J, Schwarz, Anne K   +5 more
core   +2 more sources

Diagnostic and prognostic value of scavenger receptor class B type 1 in clear cell renal cell carcinoma

Tumor Biology, 2017
Aberrant expression of scavenger receptor class B type 1 has been reported in several human cancers. Nevertheless, the roles of scavenger receptor class B type 1 in clear cell renal cell carcinoma remain unclear. The aim of this study was to evaluate the
Guanghua Xu, Ning Lou, Yuchen Xu, Hangchuan Shi, Hailong Ruan, Wen Xiao, Lei Liu, Haibing Xiao, Bin Qiu, Lin Bao, Changfei Yuan, Ke Chen, Hongmei Yang, Xiaoping Zhang   +13 more
doaj   +1 more source

CXCL16 and oxLDL are induced in the onset of diabetic nephropathy [PDF]

, 2009
Diabetic nephropathy (DN) is a major cause of end-stage renal failure worldwide. Oxidative stress has been reported to be a major culprit of the disease and increased oxidized low density lipoprotein (oxLDL) immune complexes were found in patients with ...
Abdel-Aziz, Abdel-Aziz H., Abdel-Bakky, Mohamed Sadek, Amann, Kerstin Ute, Beckmann, Janet, Doberstein, Kai, Doller, Anke, El Sayed, El Sayed M., Gutwein, Paul, Kämpfer-Kolb, Nicole, Pfeilschifter, Josef Martin, Schramme, Anja, Schäfer, Liliana   +11 more
core   +1 more source

Scavenger Receptors and Their Potential as Therapeutic Targets in the Treatment of Cardiovascular Disease

International Journal of Hypertension, 2010
Scavenger receptors act as membrane-bound and soluble proteins that bind to macromolecular complexes and pathogens. This diverse supergroup of proteins mediates binding to modified lipoprotein particles which regulate the initiation and progression of ...
Sam L. Stephen, Katie Freestone, Sarah Dunn, Michael W. Twigg, Shervanthi Homer-Vanniasinkam, John H. Walker, Stephen B. Wheatcroft, Sreenivasan Ponnambalam   +7 more
doaj   +1 more source

Initiation of hepatitis C virus infection is dependent on cholesterol and cooperativity between CD81 and scavenger receptor B type I. [PDF]

, 2006
In the past several years, a number of cellular proteins have been identified as candidate entry receptors for hepatitis C virus (HCV) by using surrogate models of HCV infection.
Barth, Heidi, Baumert, Thomas, Chisari, Francis V, Kapadia, Sharookh B, McKeating, Jane A   +4 more
core   +2 more sources

The evolution of the class A scavenger receptors

BMC Evolutionary Biology, 2012
Background The class A scavenger receptors are a subclass of a diverse family of proteins defined based on their ability to bind modified lipoproteins. The 5 members of this family are strikingly variable in their protein structure and function, raising ...
Whelan Fiona J, Meehan Conor J, Golding G Brian, McConkey Brendan J, E Bowdish Dawn M   +4 more
doaj   +1 more source

Scavenger receptor mediates systemic RNA interference in ticks. [PDF]

PLoS ONE, 2011
RNA interference is an efficient method to silence gene and protein expressions. Here, the class B scavenger receptor CD36 (SRB) mediated the uptake of exogenous dsRNAs in the induction of the RNAi responses in ticks.
Kyaw Min Aung, Damdinsuren Boldbaatar, Rika Umemiya-Shirafuji, Min Liao, Xuan Xuenan, Hiroshi Suzuki, Remil Linggatong Galay, Tetsuya Tanaka, Kozo Fujisaki   +8 more
doaj   +1 more source

Scavenger receptor B type 1: expression, molecular regulation, and cholesterol transport function

Journal of Lipid Research, 2018
Cholesterol is required for maintenance of plasma membrane fluidity and integrity and for many cellular functions. Cellular cholesterol can be obtained from lipoproteins in a selective pathway of HDL-cholesteryl ester (CE) uptake without parallel ...
W. Shen, Shailendra Asthana, F. Kraemer, S. Azhar   +3 more
semanticscholar   +1 more source

Neutralizing Antibody-Resistant Hepatitis C Virus Cell-to-Cell Transmission [PDF]

, 2010
Hepatitis C virus (HCV) can initiate infection by cell-free particle and cell-cell contact-dependent transmission. In this study we use a novel infectious coculture system to examine these alternative modes of infection.
Balfe, Peter, Baumert, Thomas, Brimacombe, Claire L, Flores, Maria Victoria, Grove, Joe, Hu, Ke, Krieger, Sophie E, McKeating, Jane A, Meredith, Luke W, Syder, Andrew J, Tellinghuisen, Timothy L, Timpe, Jennifer M, Wong-Staal, Flossie   +12 more
core   +4 more sources

Hepatitis C virus cell-cell transmission and resistance to direct-acting antiviral agents [PDF]

, 2014
Hepatitis C virus (HCV) is transmitted between hepatocytes via classical cell entry but also uses direct cell-cell transfer to infect neighboring hepatocytes.
A Owsianka, A Sigal, Aleem Siddiqui, Arvind H. Patel, AS Lok, AW Tarr, B Bartolini, B Sainz Jr, C Hezode, C Lee, C Nathan, C Sarrazin, CL Brimacombe, CM Lange, CT Jones, D Masson, D Trono, EJ Gane, Eric Soulier, F Kuonen, F Poordad, F Poordad, Fei Xiao, François Habersetzer, G Koutsoudakis, H Kwon, H Yan, H Zhu, Heidi Barth, I Fofana, I Fofana, I Fofana, IA Abela, IM Jacobson, Isabel Fofana, J Grove, J Lupberger, J Witteveldt, J Zhong, Jens Bukh, JG McHutchison, JM Gottwein, JM Gottwein, JM Pawlotsky, JM Pawlotsky, JM Pawlotsky, JM Timpe, L Rong, L Zona, Laura Heydmann, LW Meredith, MB Zeisel, MB Zeisel, Michel Doffoël, Mirjam B. Zeisel, MN Zahid, MS Sulkowski, MT Catanese, N Shi, O Lenz, P Zhong, PM Trembling, Q Sattentau, S Haid, T Pietschmann, T Pietschmann, T Wakita, Thomas F. Baumert, TJ Liang, TK Scheel, V Soriano, VD Cataldo, ZY Keck   +72 more
core   +11 more sources