Results 181 to 190 of about 20,902 (246)
Human H ferritin (HuHf) is a nanocarrier for anticancer metal drugs. By cryo‐EM, a 1.51 Å structure of its adduct with Au(NHC)Cl was solved, showing a novel tetranuclear gold(I) cluster bound to Cys90 and Cys102. Short inter‐metal distances indicate aurophilic interactions.
Lucrezia Cosottini+9 more
wiley +2 more sources
Towards Polymer Composite‐Based Transient Electronic Systems
Biodegradable electronic systems are gaining attention for implantable biomedical applications, targeting disease treatment and lifespan extension. This review covers advances in biocompatible, biodegradable polymer composites using synthetic and natural polymers with conductive, semiconductive, and insulating fillers.
Gwan‐Jin Ko+5 more
wiley +1 more source
This study demonstrates that combination of phosphosensitizer‐conjugated chitosan nanoparticles and ferroptosis inducer RSL3 increases cell death in mesenchymal breast cancer cells. Data suggests that this is attributed to variations in ferroptosis‐related protein expression, lipid peroxydation and mitochondrial function.
Marek Feith+10 more
wiley +1 more source
Microalgae are emerging as sustainable and economical bioresources that can be utilized as bioinks for creating constructs with intriguing functionalities. This review discusses the properties and applications of microalgae, providing a comprehensive review of recent advancements and challenges in 3D‐printed microalgae‐based constructs for various ...
Yiwei Zou+3 more
wiley +1 more source
Nanoparticle‐Mediated Targeted Protein Degradation: An Emerging Therapeutics Technology
Targeted protein degradation (TPD) has emerged as a transformative therapeutic strategy for eliminating disease‐associated proteins, with relevance across disorders ranging from cancer to neurodegeneration. Since its inception nearly two decades ago, TPD has attracted strong academic and commercial interest, with multiple candidates advancing into ...
Andrew G. Baker+3 more
wiley +1 more source
closo‐Carboranyl Analogs of β‐Arylethylamines: Direct Synthesis from Alkenes via EnT‐Catalysis
closo‐Carboranes are icosahedral carbon‐boron clusters with unique properties and broad applicability. They particularly stand out in the context of drug development as privileged structural motifs for boron neutron capture therapy (BNCT) and as highly hydrophobic bioisosteres for the rotational volume of phenyl rings.
Fritz Paulus+8 more
wiley +1 more source
Therapeutic effect of natural products on chicken coccidiosis. Abstract The intestinal tract is the main place for animals to digest food and absorb nutrients, which also serves as the first line of defense against pathogens that invade the internal environment.
Pan Chen+6 more
wiley +1 more source
The Role of Chalcogen Bonding in Organic Dichalcogenides of Biological Interest
Experimental and theoretical studies consistently show that selenium and tellurium in dichalcogenides compounds can function as efficient chalcogen bond (ChB) donors. Their electrophilic behavior may suggest that the formation of a ChB could represent the preliminary step of the molecular mechanism resulting in the anti‐redox activity of ...
Abhishek Tripathi+9 more
wiley +1 more source
High-density lipoprotein cholesterol: how studying the 'good cholesterol' could improve cardiovascular health. [PDF]
Diaz L, Bielczyk-Maczynska E.
europepmc +1 more source