Results 181 to 190 of about 20,902 (246)

Structural Insight Into a Human H Ferritin@Gold‐Monocarbene Adduct: Aurophilicity Revealed in a Biological Context

open access: yesAngewandte Chemie, EarlyView.
Human H ferritin (HuHf) is a nanocarrier for anticancer metal drugs. By cryo‐EM, a 1.51 Å structure of its adduct with Au(NHC)Cl was solved, showing a novel tetranuclear gold(I) cluster bound to Cys90 and Cys102. Short inter‐metal distances indicate aurophilic interactions.
Lucrezia Cosottini   +9 more
wiley   +2 more sources

Towards Polymer Composite‐Based Transient Electronic Systems

open access: yesAdvanced NanoBiomed Research, EarlyView.
Biodegradable electronic systems are gaining attention for implantable biomedical applications, targeting disease treatment and lifespan extension. This review covers advances in biocompatible, biodegradable polymer composites using synthetic and natural polymers with conductive, semiconductive, and insulating fillers.
Gwan‐Jin Ko   +5 more
wiley   +1 more source

Induction of Cell Death by Combined Treatment with Photosensitizer‐Chitosan Nanoparticles and the Ferroptosis Inducer RSL3 in Breast Cancer Cell Lines

open access: yesAdvanced NanoBiomed Research, EarlyView.
This study demonstrates that combination of phosphosensitizer‐conjugated chitosan nanoparticles and ferroptosis inducer RSL3 increases cell death in mesenchymal breast cancer cells. Data suggests that this is attributed to variations in ferroptosis‐related protein expression, lipid peroxydation and mitochondrial function.
Marek Feith   +10 more
wiley   +1 more source

Architected Microalgae‐Based Matter via 3D Printing: Properties, Printing Techniques, and Applications

open access: yesAdvanced NanoBiomed Research, EarlyView.
Microalgae are emerging as sustainable and economical bioresources that can be utilized as bioinks for creating constructs with intriguing functionalities. This review discusses the properties and applications of microalgae, providing a comprehensive review of recent advancements and challenges in 3D‐printed microalgae‐based constructs for various ...
Yiwei Zou   +3 more
wiley   +1 more source

Nanoparticle‐Mediated Targeted Protein Degradation: An Emerging Therapeutics Technology

open access: yesAngewandte Chemie International Edition, Accepted Article.
Targeted protein degradation (TPD) has emerged as a transformative therapeutic strategy for eliminating disease‐associated proteins, with relevance across disorders ranging from cancer to neurodegeneration. Since its inception nearly two decades ago, TPD has attracted strong academic and commercial interest, with multiple candidates advancing into ...
Andrew G. Baker   +3 more
wiley   +1 more source

closo‐Carboranyl Analogs of β‐Arylethylamines: Direct Synthesis from Alkenes via EnT‐Catalysis

open access: yesAngewandte Chemie International Edition, Accepted Article.
closo‐Carboranes are icosahedral carbon‐boron clusters with unique properties and broad applicability. They particularly stand out in the context of drug development as privileged structural motifs for boron neutron capture therapy (BNCT) and as highly hydrophobic bioisosteres for the rotational volume of phenyl rings.
Fritz Paulus   +8 more
wiley   +1 more source

Plants, plant‐derived compounds, probiotics, and postbiotics as green agents to fight against poultry coccidiosis: A review

open access: yesAnimal Research and One Health, EarlyView.
Therapeutic effect of natural products on chicken coccidiosis. Abstract The intestinal tract is the main place for animals to digest food and absorb nutrients, which also serves as the first line of defense against pathogens that invade the internal environment.
Pan Chen   +6 more
wiley   +1 more source

The Role of Chalcogen Bonding in Organic Dichalcogenides of Biological Interest

open access: yesChemistry – An Asian Journal, EarlyView.
Experimental and theoretical studies consistently show that selenium and tellurium in dichalcogenides compounds can function as efficient chalcogen bond (ChB) donors. Their electrophilic behavior may suggest that the formation of a ChB could represent the preliminary step of the molecular mechanism resulting in the anti‐redox activity of ...
Abhishek Tripathi   +9 more
wiley   +1 more source

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