Results 231 to 240 of about 22,858 (247)

Functions of scavenger receptor class B, type I in atherosclerosis

Current Opinion in Lipidology, 2012
This review highlights the diverse roles of the high-affinity HDL receptor scavenger receptor class B, type I (SR-BI) in the modulation of global cholesterol homeostasis and vascular cell function, and the potential implications of these processes in atherosclerosis.SR-BI in the liver plays a critical role in reverse cholesterol transport and it ...
Chieko, Mineo, Philip W, Shaul
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Interaction of scavenger receptor class B type I with peroxisomal targeting receptor Pex5p

Biochemical and Biophysical Research Communications, 2003
Scavenger receptor class B type I (SR-BI) is an HDL receptor that mediates selective HDL lipid uptake. Peroxisomes play an important role in lipid metabolism and peroxisomal targeting signal type 1 (PTS1)-containing proteins are translocated to peroxisomes by the peroxisomal targeting import receptor, Pex5p.
Magnus S C, Johnson, Jenny M, Johansson, Per Arne, Svensson, Maria A I, Aberg, Peter S, Eriksson, Lena M S, Carlsson, Björn, Carlsson   +6 more
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Scavenger receptor class B type 1 gene polymorphisms and female fertility

Current Opinion in Endocrinology, Diabetes & Obesity, 2012
Multiple studies have demonstrated a role for scavenger receptor class B type 1 (SR-B1) in female fertility. Recent studies have implicated specific SR-B1 gene polymorphisms in decreased progesterone production and suboptimal fertility outcomes.The lipoprotein receptor SR-B1 has been known to mediate selective uptake of lipids into steroidogenic ...
Mindy S, Christianson, Melissa, Yates
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Role of CD36, the Macrophage Class B Scavenger Receptor, in Atherosclerosis

Annals of the New York Academy of Sciences, 2001
Abstract: Recent work in the field of atherosclerosis has greatly expanded our knowledge of the pathogenesis of this disease. Scavenger receptors, including CD36, are thought to be most important early in the disease progression during macrophage uptake of modified LDL and foam cell formation.
A C, Nicholson, J, Han, M, Febbraio, R L, Silversterin, D P, Hajjar   +4 more
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Scavenger receptor class B type I polymorphisms and peripheral arterial disease

Metabolism, 2007
Genetic variations of the scavenger receptor class B type I (SR-BI) have been demonstrated to be associated with plasma lipid parameters, anthropomorphic parameters, and coronary artery disease. We determined the frequency of 3 single-nucleotide polymorphisms within the SR-BI gene (SCARB1) in 354 patients with peripheral arterial disease (PAD) and 354 ...
Andreas, Ritsch, Gudrun, Sonderegger, Gudron, Sonderegger, Anton, Sandhofer, Ursula, Stanzl, Ursala, Stanzl, Ivan, Tancevski, Philipp, Eller, Wilfried, Schgoer, Andreas, Wehinger, Thomas, Mueller, Meinhard, Haltmayer, Josef R, Patsch, Joseph R, Patsch   +13 more
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Characterization of scavenger receptor class B

2009
Besides its housekeeping functions in all mammalian cells, cholesterol contributes to different biological functions like bile acid-, vitamin D- or steroid hormone synthesis. Thus, multiple pathways have evolved to ensure full supply of animal cells with cholesterol, involving different lipoproteins and cell surface receptors.
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Uptake and fate of class B scavenger receptor ligands in HepG2 cells

European Journal of Biochemistry, 1999
Class B scavenger receptors (SR‐Bs) interact with native, acetylated and oxidized low‐density lipoprotein (LDL, AcLDL and OxLDL), high‐density lipoprotein (HDL3) and maleylated BSA (M‐BSA). The aim of this study was to analyze the catabolism of CD36‐ and LIMPII‐analogous‐1 (CLA‐1), the human orthologue for the scavenger receptor class B type I (SR‐BI),
D, Rhainds, L, Falstrault, C, Tremblay, L, Brissette   +3 more
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CD36 in Atherosclerosis: The Role of a Class B Macrophage Scavenger Receptor

Annals of the New York Academy of Sciences, 2000
Abstract: CD36, an 88 kD transmembrane glycoprotein, is an important receptor for oxidized lipoproteins. Unlike the LDL receptor, expression of CD36 is upregulated by this pro‐atherogenic particle, and binding and uptake perpetuates a cycle of lipid accumulation and receptor expression.
A C, Nicholson, M, Febbraio, J, Han, R L, Silverstein, D P, Hajjar   +4 more
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Expression of scavenger receptor class B type I in gallbladder columnar epithelium

Journal of Gastroenterology and Hepatology, 2002
AbstractBackgroundThe lipid content of bile may be modified by the gallbladder epithelium. Recent studies indicate that cholesterol can be absorbed from bile and that this can be enhanced by apolipoprotein (apo) A‐I. SR‐BI is a multifunctional receptor capable of binding a wide array of native or modified lipoproteins, phospholipid or bile acid ...
Magnus S C, Johnson, Per-Arne, Svensson, Jan, Borén, Håkan, Billig, Lena M S, Carlsson, Björn, Carlsson   +5 more
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Scavenger Receptor Class B Type I Modulates Epileptic Seizures and Receptor α2δ-1 Expression

Neurochemical Research
Scavenger receptor class B type I (SR-BI) is abundant in adult mouse and human brains, but its function in the central nervous system (CNS) remains unclear. This study explored the role of SR-BI in epilepsy and its possible underlying mechanism. Expression patterns of SR-BI in the brains of mice with kainic acid (KA)-induced epilepsy were detected ...
Yunyi, Huang, Yuan, Gao, Zhongwen, Huang, Minxue, Liang, Yangmei, Chen   +4 more
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