Results 231 to 240 of about 20,902 (246)
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Interaction of scavenger receptor class B type I with peroxisomal targeting receptor Pex5p
Biochemical and Biophysical Research Communications, 2003Scavenger receptor class B type I (SR-BI) is an HDL receptor that mediates selective HDL lipid uptake. Peroxisomes play an important role in lipid metabolism and peroxisomal targeting signal type 1 (PTS1)-containing proteins are translocated to peroxisomes by the peroxisomal targeting import receptor, Pex5p.
Jenny M. Johansson +6 more
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Developmental expression and immune role of the class B scavenger receptor cd36 in zebrafish
Developmental & Comparative Immunology, 2016CD36 is a transmembrane glycoprotein belonging to the scavenger receptor class B family which plays crucial roles in innate immunity. Although CD36 is widely documented in mammals, the study of its functions in fish is still limited. Here we report the identification of a zebrafish cd36 homologue.
Kai Liu +7 more
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Activation of the rat scavenger receptor class B type I gene by PPARα
Molecular and Cellular Endocrinology, 2006Peroxisomal proliferator activated receptor alpha (PPARalpha) is activated by fibrate drugs which are known to protect against atherosclerosis. The present study examines the effects of PPARalpha on SR-BI expression. For this study, a rat SR-BI promoter-luciferase reporter gene construct was co-transfected into different cell lines with expression ...
Mark P. McLean, Dayami Lopez
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Scavenger receptor class B type 1 gene polymorphisms and female fertility
Current Opinion in Endocrinology, Diabetes & Obesity, 2012Multiple studies have demonstrated a role for scavenger receptor class B type 1 (SR-B1) in female fertility. Recent studies have implicated specific SR-B1 gene polymorphisms in decreased progesterone production and suboptimal fertility outcomes.The lipoprotein receptor SR-B1 has been known to mediate selective uptake of lipids into steroidogenic ...
M.M. Yates, Mindy S. Christianson
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Hyperglycemia suppresses hepatic scavenger receptor class B type I expression
American Journal of Physiology-Endocrinology and Metabolism, 2008Hyperglycemia is a major risk factor for atherosclerotic disease. Hepatic scavenger receptor class B type I (SR-BI) binds HDL particles that mediate reverse cholesterol transport and thus lowers the risk of atherosclerosis. Here we examined glucose regulation of SR-BI gene expression in both HepG2 cells and whole animals. Results showed that hepatic SR-
Takamasa Nishiuchi +8 more
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Annals of the New York Academy of Sciences, 2000
Abstract: Scavenger‐receptor class A has been held responsible for the clearance of modified LDL from the blood circulation. However, in mice deficient in scavenger‐receptor class A, the decay in vivo of acetylated LDL (t1/2 < 2 min), as well as tissue distribution and liver uptake (at 5 min 77.4 ±6 4.6% of the injected dose) are not significantly ...
S. Nion +4 more
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Abstract: Scavenger‐receptor class A has been held responsible for the clearance of modified LDL from the blood circulation. However, in mice deficient in scavenger‐receptor class A, the decay in vivo of acetylated LDL (t1/2 < 2 min), as well as tissue distribution and liver uptake (at 5 min 77.4 ±6 4.6% of the injected dose) are not significantly ...
S. Nion +4 more
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Expression of scavenger receptor class B type I in gallbladder columnar epithelium
Journal of Gastroenterology and Hepatology, 2002AbstractBackgroundThe lipid content of bile may be modified by the gallbladder epithelium. Recent studies indicate that cholesterol can be absorbed from bile and that this can be enhanced by apolipoprotein (apo) A‐I. SR‐BI is a multifunctional receptor capable of binding a wide array of native or modified lipoproteins, phospholipid or bile acid ...
Jan Borén +5 more
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Scavenger receptor class B type I polymorphisms and peripheral arterial disease
Metabolism, 2007Genetic variations of the scavenger receptor class B type I (SR-BI) have been demonstrated to be associated with plasma lipid parameters, anthropomorphic parameters, and coronary artery disease. We determined the frequency of 3 single-nucleotide polymorphisms within the SR-BI gene (SCARB1) in 354 patients with peripheral arterial disease (PAD) and 354 ...
Andreas, Ritsch +13 more
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Class B Scavenger Receptor-Mediated Intestinal Absorption of Dietary β-Carotene and Cholesterol
Biochemistry, 2005There is now a general consensus that the intestinal absorption of water-insoluble, dietary lipids is protein-mediated, but the assignment of protein(s) to this function is still a matter of debate. To address this issue, we measured beta-carotene and cholesterol absorption in wild-type and SR-BI knockout mice and the uptake of these lipids in vitro ...
Phu Duong +9 more
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Characterisation of scavenger receptor class B type 1 in rare minnow (Gobiocypris rarus)
Fish & Shellfish Immunology, 2019Scavenger receptor class B type 1 (SRB1) is a transmembrane protein belonging to the scavenger receptors (SRs) family and it plays an important role in viral entry. Not much is known on SRB1 in teleost fish. Grass carp reovirus (GCRV) cause huge economic losses in grass carp industry.
Rong Huang +5 more
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